Accès ouvert
2025
article
OpenAlex
Gerrit Seifert, Frank Erdnüß, Wolfgang Kamin, Irene Krämer
Background: Off-label nebulization of tranexamic acid (TXA) solution is common practice for the treatment of hemoptysis. However, data regarding nebulization protocols, resulting aerodynamic parameters of the generated aerosol, and corresponding biopharmaceutical parameters are missing. The aim of this in vitro study was …
de
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Accès ouvert
2025
article
OpenAlex
Wolfgang Kamin, Georg Seifert, Karl Zwiauer, Jan Bonhoeffer et autres
Background The need to reduce the inappropriate use of antibiotics for the treatment of pediatric acute respiratory tract infections (ARTIs) calls for therapeutic alternatives. The use of herbal medicines (phytopharmaceuticals) to treat ARTIs has increased worldwide. However, the evidence of phytopharmaceutical treatment, …
de, at, ch, be, it, us, vn, tr
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Accès ouvert
2024
review
OpenAlex
Karl Zwiauer, Petra Funk, Andrea Zimmermann, Walter Lehmacher et autres
Abstract Objective In the pediatric population, acute bronchitis (AB) is a leading cause of illness absence from childcare, school, or apprenticeship. We report a meta-analysis of double-blind, randomized trials with children and adolescents with AB (aged 1–18 years), who were treated with …
at, de, pl
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Accès ouvert
2024
article
OpenAlex
Maren Doenhardt, Markus Hufnagel, Natalie Diffloth, Johannes Hübner et autres
By means of a nationwide, prospective, multicenter, observational cohort registry collecting data on 7375 patients with laboratory-confirmed SARS-CoV-2 admitted to children's hospitals in Germany, March 2020-November 2022, our study assessed the clinical features of children and adolescents hospitalized due to SARS-CoV-2, evaluated …
de, at
(code pays fourni par la source)
2023
conference-abstract
OpenAlex
Frank Erdnuess, Thorsten Reineke, Wolfgang Kamin
Background: For preventive strategies and new treatment options against RSV infection, which annually affects around three million children worldwide, knowledge about seasonality and disease severity is a prerequisite. Objectives: The aim of this study was to provide clinical and epidemiological information on …
de
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Accès ouvert
2023
article
OpenAlex
Sivagurunathan Sutharsan, Stefanie Dillenhoefer, Matthias Welsner, Florian Stehling et autres
Treatment with elexacaftor/tezacaftor/ivacaftor (ETI) improves multiple clinical outcomes in people with cystic fibrosis (pwCF) with at least one F508del allele. This study evaluated the real-world impact of ETI on lung function, nutritional status, pulmonary exacerbation frequency, and sweat chloride concentrations in a …
de, at
(code pays fourni par la source)
2023
article
OpenAlex
H Matthys, Petra Funk, Andrea Zimmermann, Wolfgang Kamin
Introduction Pelargonium sidoides extract EPs ® 7630* has been shown to be efficacious and safe in acute respiratory tract infections such as acute bronchitis (AB). Its effect regarding respiratory tract and general health status according to physical examination has not yet been …
de
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Accès ouvert
2023
article
OpenAlex
Wolfgang Kamin, Ulrich Behre, Klaus F. Helm, Birgit Reling et autres
Background: DC. root extract EPs 7630 in children with acute bronchitis (AB) have been widely demonstrated. We investigated the safety and tolerability of a syrup formulation and an oral solution in pre-school children. Methods: In an open-label, randomized clinical trial (EudraCT number …
de, pl
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2022
article
OpenAlex
Jordis Trischler, Helena Donath, D. Scheele, B Schaub et autres
Einleitung Kleinkinder mit Asthma leiden überproportional häufiger unter schweren, unkontrollierten Asthma-Exazerbationen mit ärztlichen Notfallbesuchen und Krankenhauseinweisungen als Schulkinder. Schwere Exazerbationen werden durch inhalative Kortikosteroide (ICS) bei Kleinkindern nur zu 35% verhindert und treten trotz regelmäßiger Anwendung von ICS häufig auf. Tiotropium ist …
de
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Accès ouvert
2022
review
OpenAlex
Péter Kardos, Walter Lehmacher, Andrea Zimmermann, Juliette Brandes-Schramm et autres
Background: Cough is a leading symptom of viral acute respiratory infections such as acute bronchitis (AB) and the common cold (CC), which can be debilitating and may persist for several weeks. We investigated whether treatment with Pelargonium extract EPs 7630 may reduce …
de, gr, pl
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Accès ouvert
2022
review
OpenAlex
Wolfgang Kamin, W. Lehmacher, A. Zimmermann, J. Brandes Schramm et autres
The extract EPs 7630 from the roots of Pelargonium sidoides has been proven safe and effective in the treatment of acute respiratory tract infections (aRTI).The aim of this study was to perform a meta-analysis on the efficacy of EPs 7630 in patients …
de, pl, tr
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Accès ouvert
2022
article
OpenAlex
Wolfgang Kamin, Ortwin Adams, Péter Kardos, H Matthys et autres
Background: In children and adults with acute respiratory tract infections (ARTI), elevations of serum liver enzyme activities are frequently observed in clinical practice. However, epidemiological data particularly in the pediatric population are very limited. The aim of this study was to assess …
de, pl
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