Accès ouvert
2026
article
OpenAlex
Adam Staadig, Ronny Hedell, Arvid H. Gynnå, Ricky Ansell et autres
Population genetic analysis is a fundamental component in forensic genetics for ensuring the reliability and validity of DNA evidence interpretation. Here, we present a comprehensive forensic genetic analysis of a contemporary Swedish population, based on 37 autosomal, 12 X-chromosomal and 23 Y-chromosomal …
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Accès ouvert
2026
article
OpenAlex
Christina Forsberg, Ronny Hedell, Ricky Ansell, Johannes Hedman
The growing use of crime scene dogs to detect human body fluids has led to an increased number of outdoor samples being submitted to forensic DNA laboratories. The analysis of DNA in outdoor samples such as soil presents significant challenges with present …
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Accès ouvert
2026
article
OpenAlex
Siri Fagerholm, Ricky Ansell, Andreas O. Tillmar
This paper details the first successful use of Forensic Investigative Genetic Genealogy (FIGG) in Europe, which was applied to identify a double murder perpetrator in a 16-year-old unsolved case. By integrating advanced SNP typing with genetic genealogy methods, conclusive leads were generated …
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Accès ouvert
2025
article
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
BACKGROUND: The fields of ancient DNA research and forensic genetics share both methodological similarities and common challenges, particularly in the analysis of degraded DNA. Leveraging these overlaps, this study evaluates three single nucleotide polymorphisms (SNP)-based genotyping assays for analyzing challenging forensic samples: …
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Accès ouvert
2025
article
OpenAlex
Ricky Ansell, Siri Fagerholm
Sweden was in 2019 the first country outside of North America to use forensic investigative genetic genealogy (FIGG) in solving a crime. However, further use of the method was inhibited in 2021 by the Swedish Authority for Privacy Protection Authority (IMY), following …
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Accès ouvert
2025
dataset
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
Additional file 2: Table S1. DNA amount for STR analysis, Table S2. FORCE SNPs, Table S3. Force genotyping thresholds, Table S4. Sequencing metrics FORCE, Table S5. Twist and WGS genotyping thresholds, Table S6. Sequencing metrics Twist and WGS, Table S7. Discordant SNPs, …
se, no
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Accès ouvert
2025
article
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
Additional file 1: Figure S1. Insert size of mapped reads, Figure S2. Damage plots, Figure S3. CLC workflow for FORCE, Figure S4. CLC workflow for Twist, Figure S5. Genotype concordance between FORCE and Twist, Figure S6. Genotype concordance between Twist and WGS, …
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Accès ouvert
2025
other
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
Abstract Background The fields of ancient DNA research and forensic genetics share both methodological similarities and common challenges, particularly in the analysis of degraded DNA. Leveraging these overlaps, this study evaluates three single nucleotide polymorphisms (SNP)-based genotyping assays for analyzing challenging forensic …
se, no
(code pays fourni par la source)
Accès ouvert
2025
dataset
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
Additional file 2: Table S1. DNA amount for STR analysis, Table S2. FORCE SNPs, Table S3. Force genotyping thresholds, Table S4. Sequencing metrics FORCE, Table S5. Twist and WGS genotyping thresholds, Table S6. Sequencing metrics Twist and WGS, Table S7. Discordant SNPs, …
se, no
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
Additional file 1: Figure S1. Insert size of mapped reads, Figure S2. Damage plots, Figure S3. CLC workflow for FORCE, Figure S4. CLC workflow for Twist, Figure S5. Genotype concordance between FORCE and Twist, Figure S6. Genotype concordance between Twist and WGS, …
se, no
(code pays fourni par la source)
Accès ouvert
2025
other
OpenAlex
Adam Staadig, Maja Krzewińska, Maja Sidstedt, Daniel Kling et autres
Abstract Background The fields of ancient DNA research and forensic genetics share both methodological similarities and common challenges, particularly in the analysis of degraded DNA. Leveraging these overlaps, this study evaluates three single nucleotide polymorphisms (SNP)-based genotyping assays for analyzing challenging forensic …
se, no
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Linda Jansson, Siri Fagerholm, Emelie Börkén, Arvid H. Gynnå et autres
In recent years, more sophisticated DNA technologies for genotyping have enabled considerable progress in various fields such as clinical genetics, archaeogenetics and forensic genetics. DNA samples previously rejected as too challenging to analyze due to low amounts of degraded DNA can now …
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