Eng Kok Ong

Plasma AR Alterations and Timing of Intensified Hormone Treatment for Prostate Cancer

Gianmarco Leone, Francesco Orlando, Peter Dutey‐Magni, Osvaldas Vainauskas et autres

This randomized clinical trial explores whether hormone intensification at start of androgen deprivation therapy alters selection of androgen receptor (AR) gene alterations within the gene body and/or enhancer region.

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Smart Functional Literacy Using ICT to Promote Mother Tongue Language and Inclusive Development among Ethnic Girls and Women in Northern Thailand

Kamolrat Intaratat, Piyachat Lomchavakarn, Eng Kok Ong, Khar Ng et autres

This article reports on the results of a participatory action research study that aimed to explore the socio-economic context, Smart Functional literacy, Language Literacy, and ICT literacy of ethnic girls and women in Northern Thailand. Qualitative research methods were used, including documentary

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Enhancing Essential Skills in Basic Education for Sustainable Future: Case Analysis with Exemplars Related to Local Wisdom

Khar Ng, Phaik Kim, Yoon Lay, Yee Pang et autres

Supporting a quality basic education incorporating the 21st century curriculum to reach out to all including the marginalized groups has been a key priority globally including SEAMEO regions, especially for the past few decades. However, in the advent of the digital era …

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Lineage-specific RUNX3 hypomethylation marks the preneoplastic immune component of gastric cancer

Bayzar Kurklu, Robert H. Whitehead, Eng Kok Ong, Toshinari Minamoto et autres

Runt domain transcription factor 3 (RUNX3) is widely regarded as a tumour-suppressor gene inactivated by DNA hypermethylation of its canonical CpG (cytidine-phosphate-guanidine) island (CGI) promoter in gastric cancer (GC). Absence of RUNX3 expression from normal gastric epithelial cells (GECs), the progenitors to …

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High histone variant H3.3 content in mouse prospermatogonia suggests a role in epigenetic reformatting

Michelle C. W. Tang, Steve Binos, Eng Kok Ong, Lee H. Wong et autres

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Spectrometry Mass Streptococcus pneumoniae by Use of Multilocus Sequence Typing of

J. Clin, Kim Mulholland, Catherine Satzke, Suparat Phuanukoonnon et autres

Multilocus Sequence Typing of Streptococcus pneumoniae by Use of Mass Spectrometry

Eileen Margaret Dunne, Eng Kok Ong, Ralf Moser, Peter Max Siba et autres

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Acceleration of flowering in Arabidopsis thaliana by Cape Verde Islands alleles of FLOWERING H is dependent on the floral promoter FD

Noorina Seedat, Adrian Dinsdale, Eng Kok Ong, Anthony R. Gendall

Flowering time in the model plant Arabidopsis thaliana is regulated by both external environmental signals and internal developmental pathways. Natural variation at the FLOWERING H (FLH) locus has previously been described, with alleles present in the Cape Verde Islands accession causing early …

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Multilocus Sequence Typing of Streptococcus pneumoniae by Use of Mass Spectrometry

Eileen Margaret Dunne, Eng Kok Ong, Ralf Moser, Peter Max Siba et autres

Multilocus sequence typing (MLST) is an important tool for the global surveillance of bacterial pathogens that is performed by comparing the sequences of designated housekeeping genes. We developed and tested a novel mass spectrometry-based method for MLST of Streptococcus pneumoniae. PCR amplicons …

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Interaction of Crohn's Disease Susceptibility Genes in an Australian Paediatric Cohort

Josef Wagner, Winnie Huiyan Sim, Justine A. Ellis, Eng Kok Ong et autres

Genetic susceptibility is an important contributor to the pathogenesis of Crohn's disease (CD). We investigated multiple CD susceptibility genes in an Australian paediatric onset CD cohort. Newly diagnosed paediatric onset CD patients (n = 72) and controls (n = 98) were genotyped …

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Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans

Anthony J. Peterson, Trevelyan R. Menheniott, Louise O’Connor, Anna Katrina Walduck et autres

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Helicobacter pylori Infection Promotes Methylation and Silencing of Trefoil Factor 2, Leading to Gastric Tumor Development in Mice and Humans

Anthony J. Peterson, Trevelyan R. Menheniott, Anna Katrina Walduck, James G. Fox et autres