Aline Ignácio

Unveiling a unique macrophage population in exocrine glands sustained by ILC2-derived GM-CSF

Frederike Westermann, Selma Tuzlak, Victor Kreiner, David Alejandro Bejarano et autres

Summary Granulocyte-macrophage colony-stimulating factor (GM-CSF) has a non-redundant role in the emergence and maintenance of alveolar macrophages (AMs). However, its role in developmental and steady-state myelopoiesis outside the lung is largely unexplored. Scanning through developing tissues using a Fate-map and reporter of …

ch, cz, de, us, cn, ca, gb, fr (code pays fourni par la source)

Early life microbiome influences on development of the mucosal innate immune system

Aline Ignácio, Sonia Czyz, Kathy D. McCoy

The gut microbiota is well known to possess immunomodulatory capacities, influencing a multitude of cellular signalling pathways to maintain host homeostasis. Although the formation of the immune system initiates before birth in a sterile environment, an emerging body of literature indicates that …

ca (code pays fourni par la source)

Changes in the nutritional status of elderly patients with HIV diagnosis undergoing antiretroviral treatment

Glauciane Lacerda-Miranda, Aline Ignácio, Ana Carla D. O. Lopes, Camila Faria Lima

Introduction: Acquired immunodeficiency syndrome (AIDS) is an infectious contagious disease produced by the human immunodeficiency virus (HIV) that causes progressive immunosuppression, making individuals susceptible to infections and opportunistic diseases. Despite its benefits, antiretroviral therapy has side effects, such as insulin resistance, dyslipidemia, …

br (code pays fourni par la source)

Small intestinal resident eosinophils maintain gut homeostasis following microbial colonization

Aline Ignácio, Kathleen Shah, Jeremiah Bernier‐Latmani, Yasmin Köller et autres

ca, gb, ch, au (code pays fourni par la source)

Small Intestinal Resident Eosinophils Maintain Gut Homeostasis Following Microbial Colonisation

Kathleen Shah, Aline Ignácio, Jeremiah Bernier‐Latmani, Yasmin Köller et autres

SUMMARY Intestinal homeostasis following postnatal microbial colonization requires the coordination of multiple processes including the activation of immune cells, cell-cell communication, the controlled deposition of extracellular matrix, and epithelial cell turnover and differentiation. The intestine harbors the largest frequency of resident eosinophils …

gb, ch, ca, au (code pays fourni par la source)

The emerging roles of eosinophils in mucosal homeostasis

Kathleen Shah, Aline Ignácio, Kathy D. McCoy, Nicola Laraine Harris

gb, ch, ca, au (code pays fourni par la source)

Role of the Microbiome in Intestinal Barrier Function and Immune Defense

Aline Ignácio, Fernanda Fernandes Terra, Ingrid Kazue Mizuno Watanabe, Paulo José Basso et autres

br (code pays fourni par la source)

Microbiota and Type 2 immune responses

Kathy D. McCoy, Aline Ignácio, Markus B. Geuking

ca, br (code pays fourni par la source)

Effects of formaldehyde exposure on the development of pulmonary fibrosis induced by bleomycin in mice

Mayara Peres Leal, Robson Alexandre Brochetti, Aline Ignácio, Niels Olsen Saraiva Câmara et autres

Environmental and Occupational pollution has been extensively studied because of its serious implications on the human health. Formaldehyde (FA) is a pollutant widely employed in several industries and also in anatomy, pathology and histology laboratories. Studies have shown the correlation between FA …

br (code pays fourni par la source)

Multilocus sequence typing analyses of Clostridium perfringens type A strains harboring tpeL and netB genes

Viviane Nakano, Aline Ignácio, Luis Llanco, Vanessa Bueris et autres

Clostridium perfringens is an anaerobic bacterium ubiquitous in various environments, especially in soil and the gastrointestinal tract of healthy humans and animals. In this study, multilocus sequence typing protocol was used to investigate genotypic relationships among 40 C. perfringens strains isolated from …

br, gb (code pays fourni par la source)

Innate lymphoid cells in tissue homeostasis and diseases

Aline Ignácio, Cristiane Naffah Souza Breda, Niels Olsen Saraiva Câmara

Innate lymphoid cells (ILCs) are the most recently discovered family of innate immune cells. They are a part of the innate immune system, but develop from the lymphoid lineage. They lack pattern-recognition receptors and rearranged receptors, and therefore cannot directly mediate antigen …

br, gb (code pays fourni par la source)

Alterations of Intestinal Microbiome by Antibiotic Therapy in Hospitalized Children

Miriam R. Fernandes, Aline Ignácio, Viviane Aparecida Arenas Rodrigues, Franciso C. Groppo et autres

The administration of antimicrobial agents leads to an ecological imbalance of the host-microorganisms relationship, and it causes a rapid and significant reduction in the microbial diversity. The aim of the current study was to evaluate the impact of antibiotic therapy on intestinal …

br, us (code pays fourni par la source)