Leonard D. Schaeffer

The impact of antiphospholipid antibody syndrome and/or systemic lupus erythematosus on first trimester combined screening for preterm preeclampsia – data from the IPSISS cohort

Fabienne Trottmann, P. Challande, Thabea Musik, Seyyed Mojtaba Mohaddes Ardabili et autres

Objectives: The FMF preeclampsia screening combines maternal and biochemical factors.Maternal co-morbidities such as lupus erythematosus(SLE) and anti-phospholipid syndrome(APS) are part of this model. Our aim was to examine the prevalence and impact of APS/SLE in our cohort. Materials and methods: Patients in …

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Screening for fetal growth restriction (FGR) by combined screening for preeclampsia (PE) – results from the IPSISS cohort

Thabea Musik, K. Dollt, Gwendolin Manegold‐Brauer, Fabienne Trottmann et autres

Problemstellung First trimester combined screening for fetal growth restriction (FGR) is a two-dimensional screening algorithm based on the same parameters as first trimester combined screening for preeclampsia (PE). The detection rate (DR) of FGR occurring in the context of PE is higher …

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Fetal Assessment in Pregnancy (Indication and Methodology for Fetal Monitoring in a Low-risk Population). Guideline of the DGGG, DEGUM, OEGGG and SGGG (S3-Level, AWMF Registry No. 015/089, February 2023)

Sven Schiermeier, Constantin Sylvius von Kaisenberg, Sven Kehl, Frank A. Reister et autres

Abstract Purpose The aim of this guideline was to find evidence on whether carrying out Doppler examinations and CTGs in low-risk cohorts of pregnant women improves outcomes. Methods First, a systematic search for guidelines was carried out. Identified guidelines were evaluated using …

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Vital Directions for Health and Health Care

Victor J. Dzau, Mark McClellan, James Michael McGinnis, Sheila P. Burke et autres

Importance: Recent discussion has focused on questions related to the repeal and replacement of portions of the Affordable Care Act (ACA). However, issues central to the future of health and health care in the United States transcend the ACA provisions receiving the …

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Vital Directions for Health and Health Care: Priorities from a National Academy of Medicine Initiative

Victor J. Dzau, Mark McClellan, Sheila P. Burke, Molly Joel Coye et autres

Using the Fib-4 Score to Monitor Morbidity and Mortality Risk in Chronic Hepatitis C Patients

Jeffrey S. McCombs, Tara Matsuda, Ivy Q. Tonnu-Mihara, Sammy Saab et autres

Introduction: In the recent past, many patients with chronic Hepatitis C infections (HCV) delayed treatment until symptoms emerged due to significant, direct and indirect costs associated with older treatments. Physicians may have acquiesced to delays in therapy as clinical research data on …

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Letter to the editor Essential need for research in hepatitis C

J.S. McCombs, Leonard D. Schaeffer

IMPACT OF INPUT VARIANCE ON POPULATION-BASED MICROSIMULATION RESULTS

Barbara A. Blaylock, Leonard D. Schaeffer

Population-based microsimulations often incorporate multiple data sources and modeling techniques. Results from these complex models should include uncertainty from model inputs. This work examines the confidence of reported results from population-based microsimulations using the Future Elderly Model, a dynamic microsimulation that forecasts …

If Accountable Care Organizations Are the Answer, Who Should Create Them?

Victor R. Fuchs, Leonard D. Schaeffer

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Benefit Design Should Reflect Value

Leonard D. Schaeffer, Dana P. Goldman

Bending the curve: effective steps to address long-term healthcare spending growth.

Joseph R. Antos, John M. Bertko, Michael E. Chernew, David Cutler et autres

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HHS in the 21st Century: Charting a New Course for a Healthier America

Leonard D. Schaeffer, Andrea M. Schultz, Judith A. Salerno

The U.S. Department of Health and Human Services (HHS) profoundly affects the lives of all Americans. Its agencies and programs protect against domestic and global health threats, assure the safety of food and drugs, advance the science of preventing and conquering disease, …