2022
article
OpenAlex
Christoph Weigel, Esko A. Kautto, Elshafa H. Ahmed, Yue-Zhong Wu et autres
Epstein Barr Virus (EBV) is a gammaherpesvirus responsible for a broad spectrum of human diseases, including hematologic malignancies and autoimmune disorders. EBV maintains lifelong infection by entering an endosomal state of latency inside its host cell. In response to external stimuli EBV …
us
(code pays fourni par la source)
2021
conference-abstract
OpenAlex
Brian Giacopelli, Salma Abdelbaky, Kyoko Yamaguchi, Jessica Kohlschmidt et autres
Abstract Genetic profiling of leukemic cells forms the basis for risk stratification in acute myeloid leukemia (AML). Genetic markers in AML are used to make recommendations for distinct treatment approaches, such as remission consolidation with chemotherapy rather than stem cell transplant for …
us
(code pays fourni par la source)
Accès ouvert
2021
preprint
OpenAlex
Brian Giacopelli, Min Wang, Ada C Cleary, Yue-Zhong Wu et autres
Acute myeloid leukemia (AML) is a molecularly complex disease characterized by heterogeneous tumor genetic profiles and involving numerous pathogenic mechanisms and pathways. Integration of molecular data types across multiple patient cohorts may advance current genetic approaches for improved subclassification and understanding of …
us, de
(code pays fourni par la source)
2019
conference-abstract
OpenAlex
Brian Giacopelli, Min Wang, Ada C Cleary, Yue-Zhong Wu et autres
Background Acute myeloid leukemia (AML) is a clinically and molecularly heterogeneous disease with poor survival. Recurrent genetic aberrations, such as chromosomal rearrangements and gene mutations, are currently used for patient classification and prognosis, and form the basis of our current understanding of …
us
(code pays fourni par la source)