Gabriele Cordoni

Beyond the Valve Itself: Extra-valvular Phenotyping in Mitral Stenosis: A Novel Pathophysiology-driven Echocardiographic Staging System

Gabriele Cordoni, Dania Mohty, Anastasia Shchendrygina, Domenico Galzerano et autres

Current guideline-based classifications of mitral stenosis rely primarily on parameters ofvalvular narrowing and its associated clinical symptoms. In recent years, novel phenotyping approaches based on the concept of sequential cardiac chamber involvement have been developed for other cardiovascular conditions, including mitral regurgitation, …

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Coronary Computed Tomography Angiography in Non-ST Elevation Acute Coronary Syndromes: Present Evidence and Potential Advances

Dan-Alexandru Cozac, Maria Teresa Savo, Gabriele Cordoni, Martina Palmisano et autres

Abstract Coronary computed tomography angiography (CCTA) has evolved significantly over the past decade, expanding from stable coronary artery disease (CAD) assessment to diverse cardiovascular applications. However, its role in non-ST-elevation acute coronary syndromes (NSTE-ACSs) remains incompletely defined despite excellent diagnostic accuracy. This …

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Multidetector Computed Tomography and Aortic Stenosis: The Emerging Potential of Bridging Morphology and Severity Grading

Gabriele Cordoni, Diana Di Paolantonio, Maria Teresa Savo, Dan Alexandru Cozac et autres

Background/Objectives: Echocardiography is the reference standard for grading aortic stenosis (AS); however, it yields discordant severity estimates in up to 40% of patients. Multidetector computed tomography (MDCT)-derived methods for calculating aortic valve area (AVA) may improve diagnostic concordance, but their diagnostic performance, …

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Assessing Hybrid Aortic Valve Area As An Alternative To Echocardiography For The Diagnosis Of Aortic Stenosis: A Comparative Study

Gabriele Cordoni, Diana Di Paolantonio, M. Savo, Dan Alexandru Cozac et autres

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Prognostic significance of severe mitral annular calcification in aortic stenosis: implications for aortic valve replacement outcome

Valeria Pergola, Dan Alexandru Cozac, Maria Teresa Savo, Saima Mushtaq et autres

Background: Mitral annulus calcification (MAC) is no longer seen as merely age-related. Recent evidence links MAC to calcific aortic stenosis (AS), but its prognostic value in AS patients undergoing aortic valve replacement (AVR) remains unclear. This study aims to assess the impact …

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Clinical Impact of P2Y12 Pretreatment in ST-Segment Elevation Myocardial Infarction: Insights from the SEMPRE (St-Elevation Mestre Pretreatment Registry) Study

Francesco Gallo, Ada Cutolo, Antonio Antonucci, Gabriele Cordoni et autres

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Ct-based Total Calcium Score as a Predictor of Major Cardiovascular Events: Understanding Calcification Burden in Severe Aortic Stenosis

M. Savo, Valeria Pergola, M. De Amicis, Dan Alexandru Cozac et autres

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Decoding Complexity: A Multimodal Approach in the Diagnosis of Isolated Cardiac Sarcoidosis

Elena Cozza, Benedetta Schiavon, Eleonora Lassandro, Gabriele Cordoni

Sarcoidosis is a chronic inflammatory condition of uncertain origins, affecting multiple organs and characterized by the formation of granulomas. Cardiac involvement, known as cardiac sarcoidosis (CS), occurs in 5%-10% of cases and can lead to heart failure, arrhythmias, and sudden death. Distinguishing …

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Ccta-Derived Aortic Valve Area: Bringing Morphology and Severity Grading

Gabriele Cordoni, Dan Alexandru Cozac, Diana Di Paolantonio, Maria Teresa Savo et autres

Advances in CT coronary angiography-derived plaque analysis for comprehensive assessment of ischemic heart disease

Dan-Alexandru Cozac, Eleonora Lassandro, Maria Teresa Savo, Gabriele Cordoni et autres

Abstract Coronary computed tomography angiography (CCTA) has emerged as a pivotal non-invasive imaging modality for detailed assessment of coronary anatomy and plaque characteristics, playing a significant role in diagnosing and managing ischemic heart disease (IHD). Traditional approaches, such as the Segment Stenosis …

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Cardiac Computed Tomography Detected the Hidden Culprit of a Cryptogenic Stroke: A “Cold” Case

Gabriele Cordoni, Morena De Amicis, Maria Teresa Savo, Raffaella Motta

Around 25%-40% of ischemic strokes are cryptogenic, with no identifiable cause despite thorough evaluation. The mechanisms behind cryptogenic strokes are often embolic, frequently originating from occult cardiac sources. An unroofed coronary sinus (UCS), a rare congenital anomaly, involves a partial or complete …

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Transforming Heart Failure Management: The Power of Strain Imaging, 3D Imaging, and Vortex Analysis in Echocardiography

Domenico Galzerano, Maria Teresa Savo, Biagio Castaldi, Naji Kholaif et autres

Heart failure (HF) remains a critical global health challenge, necessitating advancements in diagnostic and therapeutic strategies. This review explores the evolution of imaging technologies and their impact on HF management, focusing on three-dimensional echocardiography (3DE), myocardial strain imaging, and vortex dynamics imaging. …

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