Premkumar Sundaram

Semaglutide as an add-on treatment to optimise glycaemic control in children and young people with type 1 diabetes (smile T1D trial) development and protocol

Kun Hu, Sheriden Bevan, William McKinnon, Eleni Gkini et autres

Gene expression signature predicts rate of type 1 diabetes progression

Tomi Suomi, Inna Starskaia, Ubaid Ullah, Omid Rasool et autres

BACKGROUND: Type 1 diabetes is a complex heterogenous autoimmune disease without therapeutic interventions available to prevent or reverse the disease. This study aimed to identify transcriptional changes associated with the disease progression in patients with recent-onset type 1 diabetes. METHODS: Whole-blood samples …

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Purulent pericarditis and mediastinal abscess in a young infant

Khuen Foong Ng, Ashanti Sham Bala Krishnan, Gregory James Skinner, Premkumar Sundaram

A thriving, previously healthy 3-month-old girl presented with a 4-day history of fever, irritability and poor feeding. On admission, she was tachycardic, had cool peripheries with normal central perfusion, pulse volume and blood pressure. There was no obvious source of infection from …

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Rare association of type 1 diabetes mellitus (T1DM) with tubulo-interstitial nephritis and uveitis (TINU) and hypercalcaemia

Tatyana Moshanova, Sonal Kapoor, Sudarshana De, Premkumar Sundaram

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Review of diabetes antibody profile in children and young people with diabetes

Nehal Thanawala, Premkumar Sundaram, Vaitsa Tziaferi, James E. Greening

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Comparison of Insulin sensitivity measures between overweight and obese children and adolescents of South Asian and White Caucasian ethnicity

Savitha Shenoy, Premkumar Sundaram, James E. Greening, Vaya Tziaferi

Searchable abstracts of presentations at key conferences in endocrinology ISSN 1470-3947 (print) | ISSN 1479-6848 (online)

Cluster of human parechovirus infections as the predominant cause of sepsis in neonates and infants, Leicester, United Kingdom, 8 May to 2 August 2016

Julian Wei-Tze Tang, Christopher W. Holmes, Fadwa Elsanousi, Ayushi Patel et autres

We report an unusually high number of cases (n = 26) of parechovirus infections in the cerebrospinal fluid (CSF) of neonates and infants admitted with sepsis in the United Kingdom during 8 May to 2 August 2016. Although such infections in neonates …

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Delayed diagnosis in type 1 diabetes mellitus

Premkumar Sundaram, Emma Day, Jeremy M. W. Kirk

Children with suspected type 1 diabetes mellitus (T1DM) should have same day referral to a paediatric diabetes team. 99 children (54 male; median age 10.5 years, range 0.9-15.9 years) were diagnosed with T1DM at our hospital between January 2004 and June 2007. …

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