Julian Wei-Tze Tang

Synergistic Effect of Ambient Ozone, Relative Humidity, and Temperature on Epidemic Patterns of Influenza: A Hypothesis and Its Verification

Hidekazu Nishimura, Soichiro Sakata, Julian Wei-Tze Tang, Suguru Ohmiya et autres

The mechanisms underlying seasonal patterns in influenza epidemics have long been an enigma. Our laboratory study revealed that ambient ozone significantly inactivates airborne influenza viruses synergistically with higher relative humidity and temperature. This led us to hypothesize that natural seasonal fluctuations in …

jp, gb (code pays fourni par la source)

Severe adenovirus pneumonia requiring VV-ECMO: A case series of four adults

Mohammed Badawy, Caroline Sampson, Julian Wei-Tze Tang, Oliver TR Toovey et autres

gb (code pays fourni par la source)

Protective local downward ventilation in hospital isolation rooms

Petri Kalliomäki, Hannu Koskela, Julian Wei-Tze Tang

Ventilation and supply air distribution play an important role in reducing exposure to airborne pathogens in hospital isolation rooms. Effective supply air distribution should dilute high concentrations readily close to the source and direct them away from the breathing zone of the …

fi, gb (code pays fourni par la source)

Vulnerabilities in pandemic responses

Julian Wei-Tze Tang, Paul A. Tambyah, David SC. Hui

gb, sg, hk (code pays fourni par la source)

Mechanistic modelling reveals how host immunity reshapes airborne transmission of respiratory viruses - Source code

Andre Henriques, Julian Wei-Tze Tang, Mari Heie, Nicolas Mounet et autres

ch, gb, pk (code pays fourni par la source)

Mechanistic modelling reveals how host immunity reshapes airborne transmission of respiratory viruses - Source code

Andre Henriques, Julian Wei-Tze Tang, Mari Heie, Nicolas Mounet et autres

ch, gb, pk (code pays fourni par la source)

In-flight respiratory virus transmission models need to consider pathogen biology

Julian Wei-Tze Tang

Best Prepared, Worst Outcomes: Ethnicity, Structural Inequality and Pandemic Preparedness

Daniel Pan, Ji Soo Choi, Mi Joo Choi, Julian Wei-Tze Tang

Pandemic preparedness has traditionally been assessed through technical capacity, yet COVID-19 revealed a persistent gap between preparedness on paper and outcomes in practice. This paper examines how structural inequalities, rather than scientific limitations, shaped transmission dynamics and mortality, arguing for a reframing …

gb (code pays fourni par la source)

Charting the research frontier for viral infections, immunomodulation, and dementia: a perspective on synaptic biomarkers as essential clinical trial endpoints

Chun Kiat Lee, Michael Woodward, Mark I. Hohenberg, Julian Wei-Tze Tang

The viral-inflammatory hypothesis of Alzheimer's disease offers a new paradigm, yet interventions like antivirals and vaccination present a paradox that challenge therapeutic development. This perspective examines the critical research gap concerning cerebrospinal fluid (CSF) synaptic biomarkers in immunomodulatory therapy trials. Following decades …

sg, au, gb (code pays fourni par la source)

Influenza PA Substitutions and Genetic Diversity of A(H1N1)pdm09, A(H3N2), and B/Victoria Viruses in Japan During the 2023–2024 Season

Nanjun Lee, Julian Wei-Tze Tang, Irina Chon, Fujio Kakuya et autres

We characterized influenza A(H1N1)pdm09, A(H3N2), and B/Victoria viruses circulating in Japan during 2023-2024, focusing on lineage placement relative to WHO-recommended vaccine strains and on baloxavir resistance (PA/I38T substitutions). We enrolled 210 outpatients with influenza-like illness across eight clinics in six prefectures (October …

jp, gb (code pays fourni par la source)

Learning from the COVID-19 Pandemic—Through Sharing and Collaboration

Julian Wei-Tze Tang

During the COVID-19 pandemic (which some argue is still ongoing), I led three Special Issues (SIs) that were designed to cover the talking points that arose amongst many practitioners and researchers: (1) How can we maintain our usual diagnostic services in the …

gb (code pays fourni par la source)

Duration of the serological response and effectiveness of the inactivated influenza vaccine in healthy adults aged 18–65 years: a systematic review and meta-analysis

Joshua Nazareth, Neyme Veli, Daniel Pan, Christopher Martin et autres

BACKGROUND: The protection provided by the inactivated influenza vaccine (IIV) in adults can wane during a single influenza season. We aimed to assess temporal changes in haemagglutinin inhibition assay (HAI) titres and vaccine effectiveness in healthy adults after IIV. METHODS: , and …

gb, hk (code pays fourni par la source)