Accès ouvert
2026
article
OpenAlex
Pishoy Gouda, Nadine Allyn, Ruth M. Belin, Maria Borentain et autres
The Duke Clinical Research Institute hosted a think tank, "Anti-Obesity Pharmacotherapy: Need for Guidance, Access, and Equity" in October 2024. This brought together multi-industry stakeholders to align and advance the field of obesity medications (OMs). Key themes included the need for an …
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Accès ouvert
2026
article
OpenAlex
M F Marat Fudim, Vanessa Van Empel, Tobias Zehnder, Benoît Sauty et autres
INTRODUCTION: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition with high morbidity and mortality. Accurate risk stratification is important for advancing drug development and improving clinical care. METHODS: CONFIDENT is an observational, multi-cohort study across three centres in Europe …
us, nl, se
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2025
report
OpenAlex
Nujoud Merancy, Julie Grantier, George W. Nelson, Shatel Bhakta et autres
The NASA oIice of primary responsibility for this document is the Exploration Systems Development Mission Directorate (ESDMD) Strategy and Architecture Office (SAO). Visit the Moon to Mars Architecture homepage for the latest version of this document and for more detail on NASA’s …
us
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2025
report
OpenAlex
Nujoud Merancy, Julie Grantier, George Nelson, Shatel Bhakta et autres
The NASA oIice of primary responsibility for this document is the Exploration Systems Development Mission Directorate (ESDMD) Strategy and Architecture Office (SAO). Visit the Moon to Mars Architecture homepage for the latest version of this document and for more detail on NASA’s …
us
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2025
conference-abstract
OpenAlex
Marat Fudim, Vanessa P. M. van Empel, Tobias Zehnder, Benoît Sauty et autres
Background: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition with high morbidity and mortality. Risk stratification of patients with HFpEF is important for advancing therapeutic development and improving clinical care. Research Question: Predicting overall mortality and heart failure (HF) …
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Accès ouvert
2024
conference-paper
OpenAlex
Paul Kessler
The successful performance of an ultrasound-guided interfascial or peripheral nerve block is a highly complex process. These include to visualize nervous structures, to guide the needle to the target and to deposit local anesthetic solution around the nerve. Since it is unethical …
de
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Accès ouvert
2023
article
OpenAlex
Kariem El‐Boghdadly, Éric Albrecht, Morné Wolmarans, Edward R. Mariano et autres
BACKGROUND: Inconsistent nomenclature and anatomical descriptions of regional anesthetic techniques hinder scientific communication and engender confusion; this in turn has implications for research, education and clinical implementation of regional anesthesia. Having produced standardized nomenclature for abdominal wall, paraspinal and chest wall regional …
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Accès ouvert
2023
article
OpenAlex
Pierpaolo Pellicori, John G.F. Cleland, Maria Borentain, Jörg Täubel et autres
AIM: To investigate the effects of Cimlanod, a nitroxyl donor with vasodilator properties, on water and salt excretion after an administration of an intravenos bolus of furosemide. METHODS AND RESULTS: In this randomized, double-blind, mechanistic, crossover trial, 21 patients with left ventricular …
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2023
conference-paper
OpenAlex
Ryan Hughes, David D. McGraw, Paul Kessler, Andrew J. Choate
An initial Mars Surface Habitat (MSH) concept design study was conducted as part of the National Aeronautics and Space Administration (NASA) Habitation Systems Development Office’s effort to inform NASA crewed Mars architecture decisions. The study assessed the unique challenges, risks, and benefits …
us
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2023
conference-paper
OpenAlex
Garrett M. Carman, Michelle L. Nadeau, Emily Judd, Paul Kessler et autres
NASA’s Artemis missions aim to return humans to the Moon for the first time since the Apollo Program. Unlike the Apollo missions, Artemis missions will take advantage of pre-emplaced assets on the lunar surface to support crewed exploration, science, and utilization. Although …
us
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Accès ouvert
2023
article
OpenAlex
Arjan Konijn, César Aldecoa, Dan Benhamou, Vedran Frković et autres
BACKGROUND: The use of regional anaesthesia has increased and evolved over the past two decades but to what extent is unclear. Moreover, there is no clear standardisation of best practice in the current European landscape, which could result in inconsistencies in regional …
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Accès ouvert
2022
conference-paper
OpenAlex
Paul Kessler
In rare cases, serious complications occur after neuroaxial anaesthesia procedures. The most serious ones are haematoma, or abscess. Bleeding into the spinal canal caused by central neuraxial blocks (CNB), are rare but potentially tragic complications that may result in permanent paraplegia and …
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