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Profil bibliographique

Paul Kessler

Informations fournies par OpenAlex. Research Africa ne déduit ni nationalité, ni poste, ni coordonnées personnelles.

76Publications signalées
7730Citations signalées
2Affiliations récentes

Les institutions déclarées

Les domaines associés

Heart Failure Treatment and ManagementCardiovascular Function and Risk FactorsAnesthesia and Pain ManagementVirus-based gene therapy researchCardiac electrophysiology and arrhythmias

Les publications récentes

Accès ouvert 2026 article OpenAlex

Obesity Pharmacotherapy

Pishoy Gouda, Nadine Allyn, Ruth M. Belin, Maria Borentain et autres

The Duke Clinical Research Institute hosted a think tank, "Anti-Obesity Pharmacotherapy: Need for Guidance, Access, and Equity" in October 2024. This brought together multi-industry stakeholders to align and advance the field of obesity medications (OMs). Key themes included the need for an …

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0 citations JACC Advances
Accès ouvert 2026 article OpenAlex

CONFIDENT-HFpEF: a machine learning-based risk stratification for mortality and hospitalization using multimodal real-world data

M F Marat Fudim, Vanessa Van Empel, Tobias Zehnder, Benoît Sauty et autres

INTRODUCTION: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition with high morbidity and mortality. Accurate risk stratification is important for advancing drug development and improving clinical care. METHODS: CONFIDENT is an observational, multi-cohort study across three centres in Europe …

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1 citation ESC Heart Failure
2025 report OpenAlex

ESDMD-001: Moon to Mars Architecture Definition Document | Revision C - 2025

Nujoud Merancy, Julie Grantier, George W. Nelson, Shatel Bhakta et autres

The NASA oIice of primary responsibility for this document is the Exploration Systems Development Mission Directorate (ESDMD) Strategy and Architecture Office (SAO). Visit the Moon to Mars Architecture homepage for the latest version of this document and for more detail on NASA’s …

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1 citation
2025 report OpenAlex

ESDMD-001: Moon to Mars Architecture Definition Document | Revision C - 2025

Nujoud Merancy, Julie Grantier, George Nelson, Shatel Bhakta et autres

The NASA oIice of primary responsibility for this document is the Exploration Systems Development Mission Directorate (ESDMD) Strategy and Architecture Office (SAO). Visit the Moon to Mars Architecture homepage for the latest version of this document and for more detail on NASA’s …

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1 citation
2025 conference-abstract OpenAlex

Abstract 4345167: A Contemporary Machine Learning-Based Risk Stratification for Mortality and Hospitalization in Heart Failure with Preserved Ejection Fraction Using Multimodal Real-World Data

Marat Fudim, Vanessa P. M. van Empel, Tobias Zehnder, Benoît Sauty et autres

Background: Heart failure with preserved ejection fraction (HFpEF) is a heterogeneous condition with high morbidity and mortality. Risk stratification of patients with HFpEF is important for advancing therapeutic development and improving clinical care. Research Question: Predicting overall mortality and heart failure (HF) …

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0 citations Circulation
Accès ouvert 2023 article OpenAlex

Standardizing nomenclature in regional anesthesia: an ASRA-ESRA Delphi consensus study of upper and lower limb nerve blocks

Kariem El‐Boghdadly, Éric Albrecht, Morné Wolmarans, Edward R. Mariano et autres

BACKGROUND: Inconsistent nomenclature and anatomical descriptions of regional anesthetic techniques hinder scientific communication and engender confusion; this in turn has implications for research, education and clinical implementation of regional anesthesia. Having produced standardized nomenclature for abdominal wall, paraspinal and chest wall regional …

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43 citations Regional Anesthesia & Pain Medicine
Accès ouvert 2023 article OpenAlex

Impact of Vasodilators on Diuretic Response in Patients with Congestive Heart Failure: A Mechanistic Trial of Cimlanod (BMS-986231)

Pierpaolo Pellicori, John G.F. Cleland, Maria Borentain, Jörg Täubel et autres

AIM: To investigate the effects of Cimlanod, a nitroxyl donor with vasodilator properties, on water and salt excretion after an administration of an intravenos bolus of furosemide. METHODS AND RESULTS: In this randomized, double-blind, mechanistic, crossover trial, 21 patients with left ventricular …

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18 citations European Journal of Heart Failure
2023 conference-paper OpenAlex

Mars Surface Habitat Concept Design

Ryan Hughes, David D. McGraw, Paul Kessler, Andrew J. Choate

An initial Mars Surface Habitat (MSH) concept design study was conducted as part of the National Aeronautics and Space Administration (NASA) Habitation Systems Development Office’s effort to inform NASA crewed Mars architecture decisions. The study assessed the unique challenges, risks, and benefits …

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0 citations
Accès ouvert 2023 article OpenAlex

Regional anaesthesia practices: insights from a European survey

Arjan Konijn, César Aldecoa, Dan Benhamou, Vedran Frković et autres

BACKGROUND: The use of regional anaesthesia has increased and evolved over the past two decades but to what extent is unclear. Moreover, there is no clear standardisation of best practice in the current European landscape, which could result in inconsistencies in regional …

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3 citations European Journal of Anaesthesiology Intensive Care
Accès ouvert 2022 conference-paper OpenAlex

SP32 Neuraxial emergencies: diagnosis & management

Paul Kessler

In rare cases, serious complications occur after neuroaxial anaesthesia procedures. The most serious ones are haematoma, or abscess. Bleeding into the spinal canal caused by central neuraxial blocks (CNB), are rare but potentially tragic complications that may result in permanent paraplegia and …

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0 citations

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