Hiromasa Goto

EP1129 - ECE_1352 - Anti-rabphilin-3A antibody–positive arginine vasopressin deficiency after COVID-19 infection and vaccination: evidence for autoimmune hypothalamic–neurohypophyseal inflammation

Yoshihisa Sugimura, Yuka Natsuki, Hiroki Takizawa, Hiromasa Goto et autres

Abstract Background Arginine vasopressin deficiency (AVP-D) has been increasingly reported after coronavirus disease 2019 (COVID-19) infection and SARS-CoV-2 vaccination. However, most published cases have been described as idiopathic or post-infectious, and the underlying etiology remains largely unresolved. Anti-rabphilin-3A antibodies have recently been …

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Investigation of predictors of latent visual impairment in patients with sellar lesions

Shinichiro Teramoto, Shigeyuki Tahara, Hiromasa Goto, Takuma Kodama et autres

OBJECTIVE: Patients with sellar lesions compressing the optic nerve sometimes perceive visual improvement after lesion resection, despite the absence of visual impairment on preoperative ophthalmological examination. This study investigated the indicators of latent visual impairment in patients with sellar lesions. METHODS: Forty-five …

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A Case of Insulinoma Difficult to Differentiate from Drug-resistant Temporal Lobe Epilepsy

Eri Takagi, Tatsuya Iwamoto, Rie Nishio, Hiromasa Goto et autres

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Prevalence of unilateral hyperaldosteronism in primary aldosteronism: impact of a novel chemiluminescent immunoassay for measuring plasma aldosterone in Japan

Hiroki Kobayashi, Yoshihiro Nakamura, Masanori Abe, Toshifumi Nakamura et autres

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Adrenocortical Adenoma With Protrusion Into the Inferior Vena Cava Initially Suspected to Be Adrenocortical Carcinoma

HIROKI TAKIZAWA, Reo Higuchi, Yuki Fukumura, Muga Terasawa et autres

Adrenal tumors with invasion into the inferior vena cava (IVC) are typically malignant. Here, we present a case of adrenocortical adenoma with protrusion into the IVC. A 70-year-old man was referred to our hospital after his magnetic resonance imaging scan of the …

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Protocol of a Prospective Observational Study on Lifestyle and Quality of Life in Adults with Type 1 Diabetes in Japan

Junko Sato, Kenichi Nakajima, Tomoya Mita, Mami Koshibu et autres

INTRODUCTION: Recent studies have shown that the quality of life (QOL) of people living with type 1 diabetes (T1D) is poor and must be improved. However, the living situation and QOL of adults living with T1D in Japan have not been fully …

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Diabetic ketoacidosis due to a sensor defect of FreeStyle Libre: A case report

Toshiki Kogai, Junko Sato, Tatsuya Iwamoto, Kenichi Nakajima et autres

The FreeStyle Libre Flash Glucose Monitoring System allows users to obtain sensor glucose values by scanning with the reader or their mobile phone. We report a case of a 59-year-old man with type 1 diabetes mellitus who developed diabetic ketoacidosis due to …

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Clinical characteristics of adrenal insufficiency induced by pembrolizumab in non‐small‐cell lung cancer

Kana Kurokawa, Yoichiro Mitsuishi, Naoko Shimada, Naoaki Ito et autres

BACKGROUND AND AIM: Immune checkpoint inhibitors have significantly improved the clinical outcomes of many cancer types, but they induce a range of immune-related adverse events (irAEs). Although adrenal insufficiency (AI) is a rare irAE, it can lead to serious consequences. This study …

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Defective autophagy in vascular smooth muscle cells enhances the healing of abdominal aortic aneurysm

Akihiro Mochida, Tomoya Mita, Kosuke Azuma, Yusuke Osonoi et autres

Autophagy is an evolutionarily conserved cellular catabolic process essential for cell homeostasis, and thus its failure is associated with several diseases. While autophagy has been reported to play a role in vascular smooth muscle cells (SMCs) in vascular disorders, its precise role …

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Effects of Synbiotic Supplementation on Chronic Inflammation and the Gut Microbiota in Obese Patients with Type 2 Diabetes Mellitus: A Randomized Controlled Study

Akio Kanazawa, Masanori Aida, Yasuto Yoshida, Hideyoshi Kaga et autres

The aim of this study was to investigate the effects of 24-week synbiotic supplementation on chronic inflammation and the gut microbiota in obese patients with type 2 diabetes. We randomized 88 obese patients with type 2 diabetes to one of two groups …

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Effect of thyroxine treatment on pregnancy outcomes in infertile Japanese women with TSH levels between 2.5 μIU/mL and the upper reference limit: a retrospective study

Asako Tsunemi, Toyoyoshi Uchida, Keiji Kuroda, Yuko Ikemoto et autres

Recent randomized controlled studies have revealed that levothyroxine (LT4) treatment improves pregnancy outcomes only in infertile women with subclinical hypothyroidism who have thyroid autoantibodies (TAs), but not for those with high TSH levels within the normal range who have TAs. Here, we …

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Influence of Short-Term Dietary and Therapeutic Iodine Restriction on the Therapeutic Effects of Radioactive Iodine Therapy in Patients with Graves' Disease

Rie Nishio, Toyoyoshi Uchida, Luka Suzuki, Hiroyuki Onose et autres

Background: Several studies have investigated the factors affecting the effects of radioactive iodine ( 131 I) treatment (RAIT) in patients with Graves' disease. However, the influence of dietary or therapeutic iodine on the effect of RAIT has not been fully elucidated yet. …

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