Monika Wolf

Mutual reinforcement of lymphotoxin-driven myositis and impaired autophagy in murine muscle

Juliane Bremer, Judith Nagel, Jana Zschüntzsch, Kamil K. Zajt et autres

Inclusion body myositis (IBM) is a progressive muscle disorder characterized by inflammation and degeneration with altered proteostasis. To better understand the interrelationship between these two features, we aimed to establish a novel preclinical mouse model. First, we used quantitative PCR, in situ …

A Lymphotoxin-Driven Pathway to Hepatocellular Carcinoma

Johannes Haybaeck, Nicolas Zeller, Monika Wolf, Achim Weber et autres

Mutual reinforcement of lymphotoxin-driven myositis and impaired autophagy in murine muscle

Juliane Bremer, Judith Nagel, Jana Zschüntzsch, Kamil K. Zajt et autres

Inclusion body myositis (IBM) is a progressive muscle disorder characterized by inflammation and degeneration with altered proteostasis. To better understand the interrelationship between these two features, we aimed to establish a novel preclinical mouse model. First, we used quantitative PCR, in situ …

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Endothelial CCR2 Signaling Induced by Colon Carcinoma Cells Enables Extravasation via the JAK2-Stat5 and p38MAPK Pathway

Monika Wolf, Alexandra Hoos, Judith Bauer, Steffen Boettcher et autres

Human CD34+-derived plasmacytoid dendritic cells as surrogates for primary pDCs and potential cancer immunotherapy

Giovanna Fiore, Wolfgang Weckwarth, Kerstin Paetzold, Llucia Albertí Servera et autres

Introduction Plasmacytoid dendritic cells (pDCs) are capable of triggering broad immune responses, yet, their scarcity in blood coupled to their reduced functionality in cancer, makes their therapeutic use for in situ activation or vaccination challenging. Methods We designed an in vitro differentiation …

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Intestinal B cells license metabolic T-cell activation in NASH microbiota/antigen-independently and contribute to fibrosis by IgA-FcR signalling

Elena Kotsiliti, Valentina Leone, Svenja Schuehle, Olivier Govaere et autres

BACKGROUND & AIMS: The progression of non-alcoholic steatohepatitis (NASH) to fibrosis and hepatocellular carcinoma (HCC) is aggravated by auto-aggressive T cells. The gut-liver axis contributes to NASH, but the mechanisms involved and the consequences for NASH-induced fibrosis and liver cancer remain unknown. …

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Author Correction: Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Mohsen Malehmir, Dominik Pfister, Suchira Gallage, Marta Szydlowska et autres

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„Sprachwissenschaft [...] etwas für Leute, welche die Pedanterie zur Mathematik hätten, nicht jedoch die Intelligenz. Leute, die sich ihre eigene notdürftige Logik erfänden“. Auf den Spuren des Ausdrucks von Emotionen

Monika Wolf

In order to track down the devices used in the verbal expression of emotions, it is helpful to proceed semasiologically, for example by searching for emotive expressions in authentic texts. In texts written in everyday language, emotions are frequently verbalized without designating …

Approaches for deployment and access of content in delivery portals

Theresa Rauffmann, Monika Wolf

In the field of Technical Communication the focus has always been on supporting users in their search for information in a way that is appropriate for the target group. Products are becoming more and more complex, current standards require manufacturers to provide …

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Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer

Mohsen Malehmir, Dominik Pfister, Suchira Gallage, Marta Szydlowska et autres

ch, de, ca, nl, gb, es, us, au (code pays fourni par la source)

„Das könnte man gesellschaftlich so sagen, aber es wäre weiter nichts als eine vertuschende Redeweise“ (Theodor, 1. Akt, 12. Szene)

Monika Wolf

Der Beitrag analysiert einen literarischen Text mit sprachwissenschaftlichen Methoden. Er liefert eine mikrostrukturelle Beschreibung des Gesprächsverhaltens in einer hierarchisch strukturierten Gesellschaft im alten Österreich anhand einer zentralen Szene in Hofmannsthals Lustspiel Der Unbestechliche. Dabei wird untersucht, mit welchen sprachlichen Mitteln die Figuren …

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Single cell polarity in liquid phase facilitates tumour metastasis

Anna Lorentzen, Paul F. Becker, Jan Kosla, Massimo Saini et autres

Dynamic polarisation of tumour cells is essential for metastasis. While the role of polarisation during dedifferentiation and migration is well established, polarisation of metastasising tumour cells during phases of detachment has not been investigated. Here we identify and characterise a type of …

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