Bo Luo

Selective Visualization of ROR1-Positive TNBC of the Mesenchymal-Like Subtype Using Peptide-Based 68 Ga-PET Radiotracers

Yang Zhang, Wenyu Wu, Qiang Ren, Yue Wang et autres

Triple-negative breast cancer (TNBC) lacks effective molecular targets for imaging. Receptor tyrosine kinase-like orphan receptor 1 (ROR1) is overexpressed in the mesenchymal-like (claudin-low) subtype of TNBC. Here, we developed two optimized linear peptide radiotracers, DR1 and DR2, derived from the complementarity-determining regions …

cn, no (code pays fourni par la source)

Real-world outcomes and prognostic factors of minimally invasive thrombolytic and soft-channel drainage assisted by 3D Slicer for basal ganglia hemorrhage

Huaxuan Chen, Bo Luo, Yuan Zhang, Bin Shang et autres

The integration of 3D Slicer-assisted minimally invasive thrombolysis with soft-channel drainage has shown promise as a treatment strategy for basal ganglia hemorrhage (BGH). This study aimed to evaluate clinical efficacy and identify prognostic‑associated factors in patients. We retrospectively analyzed the clinical data …

Real-world outcomes and prognostic factors of minimally invasive thrombolytic and soft-channel drainage assisted by 3D Slicer for basal ganglia hemorrhage

Huaxuan Chen, Bo Luo, Yuan Zhang, Bin Shang et autres

The integration of 3D Slicer-assisted minimally invasive thrombolysis with soft-channel drainage has shown promise as a treatment strategy for basal ganglia hemorrhage (BGH). This study aimed to evaluate clinical efficacy and identify prognostic‑associated factors in patients. We retrospectively analyzed the clinical data …

Real-world outcomes and prognostic factors of minimally invasive thrombolytic and soft-channel drainage assisted by 3D Slicer for basal ganglia hemorrhage

Huaxuan Chen, Bo Luo, Yuan Zhang, Bin Shang et autres

BACKGROUND: The integration of 3D Slicer-assisted minimally invasive thrombolysis with soft-channel drainage has shown promise as a treatment strategy for basal ganglia hemorrhage (BGH). This study aimed to evaluate clinical efficacy and identify prognostic‑associated factors in patients. METHODS: We retrospectively analyzed the …

cn (code pays fourni par la source)

Development and Internal Validation of a Preliminary Risk Prediction Model for Delayed Posthemorrhagic Hydrocephalus in Patients with Intraventricular Hemorrhage

Bo Luo, Heng Dong, Qiuguo He, Haibo Ren et autres

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Efficacy of endocrine therapy alone versus endocrine therapy combined with radiotherapy after breast-conserving surgery in older patients with early-stage estrogen receptor-positive breast cancer: a meta-analysis

Xiuling Wu, Yifu Wang, Bo Luo, Xiaobin Huang et autres

BACKGROUND: In the general adult female population, the benefit of adjuvant radiotherapy following breast-conserving surgery (BCS) is well established. Nevertheless, whether radiotherapy should be routinely added after BCS for older women with estrogen receptor-positive (ER+) breast cancer remains controversial. The present meta-analysis …

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The application of probe-based confocal laser endomicroscopy in pleural diseases

Mingli Yuan, Bo Luo, Cheng Song, Yu Hu et autres

Probe-based confocal laser endomicroscopy (pCLE) constitutes a cutting-edge in vivo imaging technology, yet its application within the realm of respiratory medicine, especially of pleural disease, is still in its incipient phase. This single-center, retrospective analysis encompassed patients admitted to our department between …

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Preclinical and First-In-Human Evaluation of 68 Ga-PSMA-33, a Novel PSMA Radiotracer with Low Background Signal

Wenyu Wu, Xiaochen Yao, Fei Yu, Jiang Wu et autres

High Resolution Image Download MS PowerPoint Slide Purpose: this study aimed to investigate the potential of a novel 68 Ga-labeled PSMA-targeted radiotracer, 68 Ga-PSMA-33, as a diagnostic tool for prostate cancer in preclinical and pilot clinical studies. Methods: 68 Ga-PSMA-33 was radiolabeled …

cn, no, us (code pays fourni par la source)

Prognostic value of baseline circulating tumor DNA levels in metastatic castration-resistant prostate cancer: a systematic review and meta-analysis

Yonghe Liao, Yuxuan Lin, Bo Luo, Jinhai Shen

Background: Metastatic castration-resistant prostate cancer (mCRPC) remains a clinically aggressive and lethal disease. Circulating tumor DNA (ctDNA), as a minimally invasive biomarker, has shown prognostic utility in several solid tumors. However, its clinical relevance in mCRPC has not been comprehensively elucidated. Methods: …

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Expanded Histologic Lineage and Origin of Mesonephric-Like Adenocarcinoma: A Clinicopathologic Study of 9 Cases

Yuxiang Shi, Xiaojuan Lyu, Jing Zheng, Bo Luo et autres

Mesonephric-like adenocarcinoma (MLA) is a rare gynecologic malignancy primarily arising in the uterine corpus and ovaries. It shares remarkable similarities in its histomorphology, immunophenotype, and molecular features with mesonephric adenocarcinoma of the cervix. Controversy remains regarding whether the MLA originates from the …

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Accurate and Scalable Multimodal Pathology Retrieval via Attentive Vision-Language Alignment

Hongyi Wang, Zhengjie Zhu, Jiabo Ma, Fang Wang et autres

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Transarterial chemoembolization combined with immunotherapy and targeted therapy as first-line treatment for unresectable and non-metastatic hepatocellular carcinoma: a meta-analysis of phase III trials

Lele Wang, Bo Luo, Mingrui Zhao, Jinhai Shen

Background: The current standard treatment paradigm for patients with unresectable and non-metastatic hepatocellular carcinoma (HCC) involves transarterial chemoembolization (TACE) as the primary local therapeutic modality, followed by systemic therapy upon disease progression. Emerging evidence suggests that the concurrent integration of immunotherapy and …

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