Real-world outcomes and prognostic factors of minimally invasive thrombolytic and soft-channel drainage assisted by 3D Slicer for basal ganglia hemorrhage

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The integration of 3D Slicer-assisted minimally invasive thrombolysis with soft-channel drainage has shown promise as a treatment strategy for basal ganglia hemorrhage (BGH). This study aimed to evaluate clinical efficacy and identify prognostic‑associated factors in patients. We retrospectively analyzed the clinical data of 96 patients with spontaneous BGH. The Glasgow Coma Scale (GCS) score was assessed preoperatively and at the 6-month follow-up, during which functional status was also evaluated using the modified Rankin Scale (mRS). Independent risk factors for an unfavorable prognosis were identified using logistic regression analysis. Surgical outcomes showed a median operative time of 23 minutes, a median hospital stay of 26 days, and a median postoperative day‑3 hematoma clearance rate of 85.53%. The GCS and mRS scores improved significantly at the 6‑month follow‑up (P < 0.001), with 58.33% of patients achieving favorable outcomes. Lower preoperative GCS score, larger hematoma volume, significant compression of the lateral ventricle, thalamic involvement, and longer onset-to-surgery interval were independent risk factors (P < 0.05). Minimally invasive thrombolytic therapy combined with soft-channel drainage, assisted by 3D Slicer, is feasible and well-tolerated in patients with BGH. Dynamic evaluation of prognostic factors may help optimize clinical management and guide individual therapeutic strategies.

Ce résumé expose les affirmations des auteurs. BNTIC ne l’interprète pas comme une validation indépendante des résultats.