Ali Vasheghani Farahani

Natural bioactive molecules and chemotherapeutics synergism for enhanced cancer therapy

Mehrdad Hashemi, Katayoun Heshmatzad, Ghazaleh Shahsavan, Vahid Tavakolpour et autres

BACKGROUND: Chemotherapy remains a foundation of cancer care but is limited by multidrug resistance, systemic toxicities, and suboptimal selectivity, prompting interest in adjunctive strategies that improve efficacy and tolerability without adding significant burden to patients or healthcare systems. AIMS/OBJECTIVES: This review highlights …

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MicroRNAs and Long Non-Coding RNAs Affect the Mechanisms Involved in Age-Related Neurodegeneration in a Manner Depending on RNA-Binding Proteins

Mehrdad Hashemi, Pezhman Shafiei Asheghabadi, Mahdi Moassesfar, Saba Mashhadikhan et autres

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The Protective Approaches for High-Risk Patients Requiring Blood and Plasma-Derived Products Against Parvovirus B19

Ali Vasheghani Farahani, Farahnaz Zeinali, Asma Elahifard, H Dashti et autres

Background and ObjectivesParvovirus B19 (B19V) is a transfusion-transmissible virus that typically presents asymptomatically in healthy individuals but can cause severe clinical complications in vulnerable patients such as pregnant women, immunocompromised individuals and patients with chronic anemia.This review aims to collect the current …

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Regenerative Cardiology: Emerging Hopes Towards Restoring the Heart

Fatemeh Ghanbari, Nasim Naderi, Shahram Rabbani, Ali Vasheghani Farahani et autres

Cardiovascular diseases, particularly myocardial infarction and heart failure, continue to affect the lives of millions and pose significant global health challenges. Despite all efforts, a definitive cure to prevent the progression of heart disease has remained elusive, and all current therapies fail …

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From infection to infertility: a review of the role of human papillomavirus-induced oxidative stress on reproductive health and infertility

Omid Salahi Ardekani, Arash Letafati, Sepehr Ebrahimi Dehkordi, Ali Vasheghani Farahani et autres

Infertility has emerged as a significant global health concern, affecting nearby 8-12% of couples in reproductive age worldwide. Increasing evidence suggests a potential link between human papillomavirus (HPV) and infertility in both men and women. Some research indicate that HPV can infect …

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Zika virus tropism and pathogenesis: understanding clinical impacts and transmission dynamics

Saeed Tajik, Ali Vasheghani Farahani, Omid Salahi Ardekani, Saba Seyedi et autres

The Zika virus (ZIKV) is classified within the Flavivirus genus of the Flaviviridae family and is categorized as an arbovirus. The virus was initially identified in a rhesus monkey in Uganda in 1947 and later in a human in Nigeria in 1952. …

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Distribution of HPV genotypes in Mashhad, Iran: insights from a 2022–2023 study

Arash Letafati, Masoomeh Noroozi, Tina Fallah, Ali Vasheghani Farahani et autres

BACKGROUND: Human papillomavirus (HPV), is one of the main causes of cervical cancer and also one of the most common sexually transmitted infections (STIs). HPV is responsible for almost all cases of cervical cancer and plays a principal role in causing other …

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High prevalence of HPV-56 and HPV-39 in Sari, Iran: an analysis of genotype distribution

Arash Letafati, Ali Vasheghani Farahani, Mohammad Mostafa Baradaran Nasiri, Hossein Pourmoein et autres

BACKGROUND: Human papillomavirus (HPV) is responsible for the most common sexually transmitted infection, particularly among sexually active individuals. Understanding the geographical distribution and epidemiology of the most prevalent HPV genotypes is essential for developing effective prevention strategies. Consequently, this study aimed to …

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Correction: from discovery to treatment: tracing the path of hepatitis E virus

Arash Letafati, Zahra Taghiabadi, Mahshid Roushanzamir, Bahar Memarpour et autres

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From discovery to treatment: tracing the path of hepatitis E virus

Arash Letafati, Zahra Taghiabadi, Mahshid Roushanzamir, Bahar Memarpour et autres

The hepatitis E virus (HEV) is a major cause of acute viral hepatitis worldwide. HEV is classified into eight genotypes, labeled HEV-1 through HEV-8. Genotypes 1 and 2 exclusively infect humans, while genotypes 3, 4, and 7 can infect both humans and …

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Uncommon high distribution of HPV-16, HPV-54, and HPV-56 in female referred to a laboratory in Karaj, Iran: indications of a paradigm shift in HPV genotypes?

Arash Letafati, Saeed Motlaghzadeh, Omid Salahi Ardekani, Bahar Memarpour et autres

BACKGROUND: Human papillomavirus (HPV) is among the leading cause of sexually transmitted infections, particularly prevalent among sexually active individuals. While many HPV infections clear up over time, some may progress to various cancers such as anal cancer, cervical cancer and, vaginal cancer. …

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Headache and Dizziness as Prevailing Clinical Manifestations in Parkinson's Patients Following COVID-19

Mohammad Haddadi, Yasamin Meamarzadegan, Ali Vasheghani Farahani, Alireza Etrati Kooshali et autres

Background: The coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2), has posed significant global health challenges, particularly for vulnerable populations. Objectives: This retrospective report from the Iranian Network for Research in Viral Diseases (INRVD) investigates the common …

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