High prevalence of HPV-56 and HPV-39 in Sari, Iran: an analysis of genotype distribution
Rattachement africain : ir. Niveau de preuve : code pays fourni par la source.
Le résumé fourni par la source
BACKGROUND: Human papillomavirus (HPV) is responsible for the most common sexually transmitted infection, particularly among sexually active individuals. Understanding the geographical distribution and epidemiology of the most prevalent HPV genotypes is essential for developing effective prevention strategies. Consequently, this study aimed to examine the distribution of HPV genotypes among HPV-positive women and men in Sari, the capital city of Mazandaran province in northern Iran. MATERIALS AND METHODS: HPV DNA was extracted (PZP Company, Molecular IVD, Iran) from genital and cervical samples of the study participants. Genotyping was conducted for 90 cases utilizing the High + Low Papilloma Strip test (Operon Company, Spain). Demographic data were statistically analyzed in correlation with the virological data (STATA version 17). RESULTS: Overall, 67.7% (61 out of 90) of the cases tested positive for HPV, with 75% of those being classified as high-risk. The participant group consisted of 92% females (83) and 8% males (7). The highest HPV prevalence, 75% (36), was observed in females and males aged under 31, with the majority of positive cases belonging to high-risk genotypes. The most frequently identified genotypes were HPV-11 (23%), HPV-6 (21%), HPV-56 (18%), HPV-39 (16%), HPV-16, HPV-91, and HPV-66 each comprising (14%). HPV-56 was the most common high-risk genotype, accounting for 11 cases (18%), followed by HPV-39, which was present in 10 cases (16%). CONCLUSION: The prevalence of HPV infection was particularly high among individuals under the age of 31 for both genders, with men exhibiting a 100% infection rate. These findings emphasize the urgent need for targeted education aimed at the younger population and the implementation of infection control measures. Specifically, widespread HPV vaccination targeting HPV-6, HPV-11, HPV-39, and HPV-56 should be prioritized for the general population.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- High prevalence of HPV-56 and HPV-39 in Sari, Iran: an analysis of genotype distribution
- Date Crossref
- 20/09/2024
- Éditeur
- Springer Science and Business Media LLC
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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University of Tehran pays non établi dans la noticeUniversité ou école supérieure
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Tehran University of Medical Sciences Research Center for Clinical Virology pays non établi dans la noticeUniversité ou école supérieure
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Mazandaran University of Medical Sciences pays non établi dans la noticeUniversité ou école supérieure
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Islamic Azad University of Shahrekord Department of Microbiology pays non établi dans la noticeUniversité ou école supérieure
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Islamic Azad University Medical Branch of Tehran pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Public Health Department of Virology pays non établi dans la noticeUniversité ou école supérieure
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Faculty of Medicine Immunogenetic Research Center pays non établi dans la noticeUniversité ou école supérieure
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School of Public Health Department of Epidemiology and Biostatistics pays non établi dans la noticeUniversité ou école supérieure
University of Tehran, Research Center for Clinical Virology — Tehran University of Medical Sciences et Mazandaran University of Medical Sciences, avec 5 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.