Jianhua Tan

Mass Spectrometry Prediction Based on Few-Shot Neural Network and Chemical Prior Knowledge for Regulatory Screening of Cosmetic Glucocorticoid

Jianhua Tan, Wenyao Liang, Zemin Xia, Jian Wei et autres

Glucocorticoids are prohibited in cosmetics due to health risks, yet illegal additions persist through structural modifications that evade conventional screening. Current detection methods face critical limitations, including scarce reference standards, restricted coverage, and high training costs, presenting a global regulatory challenge. Here, …

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Periorbital aging characteristics and eye skincare behavior patterns among Chinese women: A large-sample cross-city study

Jiayi Lian, Zhifan Chen, Shujing Peng, Jianhua Tan et autres

Background The periorbital skin is particularly susceptible to aging owing to its unique anatomical structure. Daily eye skincare is widely recognized as relevant to aging management. However, research into the differences in eye skincare behavior patterns and practical solutions for Chinese women …

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Glabrol—an impurity in licorice extract—causes toxicity in muscle, bone, and immune tissues through activation of the AP-1 signaling pathway

Chenyang Jiang, X Y Feng, Mingyu Qi, Shaojuan Wu et autres

Licorice ( Glycyrrhiza genus ) is a traditional medicinal herb that has also been widely used in the food and cosmetic industries, leading to widespread human exposure. Currently, many components have been identified as active ingredients in licorice; however, the toxic impurities …

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Nontarget screening and suspect identification of organic chlorinated compounds in cosmetics and personal care products using UHPLC-Q-Orbitrap-HRMS

Tao Yang, Xinling Li, Jianhua Tan, Wenyao Liang et autres

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From Safety Evaluation to Influencing Factors Analysis: A Comprehensive Investigation on Ocular Irritation of Baby Bath Products

Qianfeng He, Peining Li, Yanhua Guo, Chengkai Mei et autres

Given the underdevelopment and sensitivity of babies’ eyes, frequently used baby bath products have garnered attention for their ocular irritation safety. The selection and application of raw materials are key factors. We tested 39 commercial baby bath products for ocular irritation safety …

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Sunscreens with Nicotinamide as Skin-Brightening Ingredient Increase Exposure Risk of UV-Filters: Quantitative Analysis of UV-Filter Skin Penetration Based on an Improved In Vivo Confocal Raman Spectroscopy Method

Wucheng Yang, Yu Xie, Chaowan Guo, Zedong Ouyang et autres

), suggesting a higher health risk of chronic use of such sunscreens.

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From screening to risk assessment: a comparative study on product usage, human burden, and potential neurotoxicity of novel paraben analogues

Lingxue Meng, Hongxuan Kuang, Jianhua Tan, Xinling Li et autres

• Non-targeted screening reveals that PhAc is a novel paraben structural analogue. • The content of PhAc in personal care products is much higher than parabens. • Children’s urinary PhAc exceeds parabens in South China populations. • PhAc burdens in children in …

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Nontarget screening and identification of emerging preservatives and their metabolites in human urine

Xinling Li, Tao Yang, Jianhua Tan, Hongxuan Kuang et autres

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Nontarget screen and identify sulfate and sulfonate surfactants in personal care products using UHPLC-Q-Orbitrap-HRMS based on fragmentation characteristics and sulfur isotopologue pattern

Xinling Li, Jianhua Tan, Wenyao Liang, Xianzhi Peng

Sulfate and sulfonate compounds are extensively used as anionic surfactants in personal care products (PCPs), which might pose adverse potential to human health. However, available research mostly identified certain subsets of sulfated and sulfonated surfactants based on target analysis. In this study, …

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Meet-in-metabonomics: Insights into associations between hair heavy metal and adverse child growth in e-waste recycling area

Hongxuan Kuang, Mengyang Li, Jiarong Wang, Jianhua Tan et autres

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Beyond plastic pollution: Unveiling chemical release from plastic debris in river water and seawater using non-target screening

Xianzhi Peng, Jing Kun Zhou, Jianhua Tan, Guangshi Chen et autres

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Profiling metabolites and exploring metabolism of parabens in human urine using non-target screening and molecular networking

Tao Yang, Xinling Li, Jianhua Tan, Wenyao Liang et autres

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