From Safety Evaluation to Influencing Factors Analysis: A Comprehensive Investigation on Ocular Irritation of Baby Bath Products
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Le résumé fourni par la source
Given the underdevelopment and sensitivity of babies’ eyes, frequently used baby bath products have garnered attention for their ocular irritation safety. The selection and application of raw materials are key factors. We tested 39 commercial baby bath products for ocular irritation safety and proposed a novel evaluation method using the “Risk Attention Index” to analyze formulation risk factors. The ocular irritation potential of 39 commonly used raw materials under typical usage conditions was investigated via animal and cell models. Results showed over 20% of commercial products had safety risks. Surfactants like cocamidopropyl betaine (CAPB), sodium laureth sulfate (SLES), and sodium lauroamphoacetate (SLA) had the highest “Risk Attention Index”, requiring special attention. Some fragrance components were also potential irritants. Combining SLES with panthenol, maltooligosyl glucoside/hydrogenated starch hydrolysate, and Tween®-28 could significantly reduce its irritation in an animal model. The same ingredients from different sources led to inconsistent irritation results. This suggests that manufacturing processes of raw materials, in addition to their chemical properties, concentration, and combination methods, all influence the ocular irritation potential. This study provides key scientific evidence for assessing ocular irritation and developing low-irritation formulations in baby bath products, thereby enhancing product safety.
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Le contrôle bibliographique ouvert
DOI retrouvé dans Crossref DOI retrouvé ; titre concordant.
- Titre Crossref
- From Safety Evaluation to Influencing Factors Analysis: A Comprehensive Investigation on Ocular Irritation of Baby Bath Products
- Date Crossref
- 03/11/2025
- Éditeur
- MDPI AG
- Type
- journal-article
Ce recoupement confirme des métadonnées liées au DOI. Il ne confirme ni la méthode ni les conclusions de l’étude, et il ne compte pas comme une seconde source scientifique indépendante.
Où se fait cette recherche
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Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality pays non établi dans la noticeUniversité ou école supérieure
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Inspection and Research Institute Guangzhou Quality Supervision pays non établi dans la noticeStructure de recherche
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Guangdong Testing Institute for Product Quality Supervision pays non établi dans la noticeUniversité ou école supérieure
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Collaborative Innovation Center for NQI-Quality Safety of Guangzhou pays non établi dans la noticeInstitution
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Guangzhou Quality Testing and Inspection Institute pays non établi dans la noticeStructure de recherche
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Kangaroo Mommy Research Centre pays non établi dans la noticeStructure de recherche
Guangdong-Hongkong-Macau Joint Laboratory of Collaborative Innovation for Environmental Quality, Guangzhou Quality Supervision — Inspection and Research Institute et Guangdong Testing Institute for Product Quality Supervision, avec 3 autres affiliations.
Une affiliation ne permet pas de déduire la nationalité d’un auteur.