Chao Zhang

Circ_0001461 Regulates Colorectal Cancer Growth, Movement and Immune Escape Through miR-532-3p/AMOTL2

Wei Zheng, Liang Hong, Chao Zhang

cn (code pays fourni par la source)

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma (Adv. Sci. 17/2025)

Ruiyang Zi, Xiang Zhao, Limei Liu, Yijie Wang et autres

Colorectal Carcinoma This study reveals that SIRT1, a metabolic regulator in colorectal cancer (CRC), enhances immunosuppression by upregulating CX3CL1 to drive TCF7+ regulatory T cell (TCF7+Treg) differentiation into potent TNFRSF9+ subsets. The cover art depicts T cells as robotic sentinels battling CRC …

The Application of Joint Classroom Discussion Case-Based Learning Teaching Method in the Field of Urology

Muhammad Abbas, Chen Huaian, Chao Zhang, Sibghat Ullah et autres

In teaching poses significant challenges for clinical doctors and medical students. Students frequently struggle to apply theoretical knowledge in real clinical contexts. We explore the joint discussion of flipped classroom in urological surgery theory teaching case-based learning (CBL) applies effects. This study …

cn, pk (code pays fourni par la source)

Feasibility Study on Self-development of Physics Teachers' Curriculum Abilities

Jing‐Tao Lü, Chuantao Ma, Chao Zhang

Currently, with the joint efforts of educators and strong support from the whole society, China's basic education has achieved great success in curriculum reform. The basic education curriculum is also constantly being reformed, among which the physics curriculum after curriculum reform has …

Metabolic‐Immune Suppression Mediated by the SIRT1‐CX3CL1 Axis Induces Functional Enhancement of Regulatory T Cells in Colorectal Carcinoma

Ruiyang Zi, Xiang Zhao, Yijie Wang, Rui Zhang et autres

Abstract Metabolic reprogramming of tumor cells dynamically reshapes the distribution of nutrients and signals in the tumor microenvironment (TME), affecting intercellular interactions and resulting in metabolic immune suppression. Increased glucose uptake and metabolism are characteristic of many tumors. Meanwhile, the progression of …

cn (code pays fourni par la source)

OUTPOST: A comprehensive analysis software for whole‐metagenome shotgun sequencing incorporating group stratification

Yihang Zhou, Jihong Zheng, Wenqi Song, Xinyi Yan et autres

The whole metagenOme shotgun seqUencing sTream Pipeline that is cOmprehensive and uSeful for mulTi groups experiments (OUTPOST) is a comprehensive analysis software for whole-metagenome shotgun sequencing incorporating group stratification, which encompasses 14 modules and boasts over 50 functions, distinguishing itself for its …

cn, hk (code pays fourni par la source)

Roles of Learning Design Tools in Scaffolding Teacher Participation and Learning in Research Practice Partnerships

Nancy Wai Ying Law, Pakon Ko, Elizabeth S. Charles, Jérémie Choquette et autres

This structured poster session brings together eight presentations of research practice partnership (RPP) projects that have designed and deployed learning design (LD) tools to scaffold teachers' learning and collaboration as designers.These tools are designed according to the design principles underpinning the respective …

hk, ca, gb, us, es, il, gr, sg, nl, cn (code pays fourni par la source)

TPD: Enhancing Student Language Model Reasoning via Principle Discovery and Guidance

Haorui Wang, Rongzhi Zhang, Yinghao Li, Lingkai Kong et autres

Large Language Models (LLMs) have recently showcased remarkable reasoning abilities. However, larger models often surpass their smaller counterparts in reasoning tasks, posing the challenge of effectively transferring these capabilities from larger models. Existing approaches heavily rely on extensive fine-tuning data or continuous …

us (code pays fourni par la source)

Human-friendly semitransparent organic solar cells achieving high performance

Zonghao Wu, Beibei Shi, Jiangsheng Yu, Mengzhen Sha et autres

We systematically evaluated the photobiological safety of mainstream ST-PV devices and fabricated a series of high-performance human-friendly ST-PV devices with LUE values exceeding 5.0% and low skin/eye damage levels for human beings.

cn, hk (code pays fourni par la source)

Recent antitumor therapy does not increase Omicron COVID-19 severity in cancer patients: a two-center retrospective study in China

Ying Liu, Wenyao Zhu, Zhiwu Wang, Jiarui Yu et autres

Background: The impact of anticancer therapy and related clinical factors on the severity of COVID-19 in cancer patients during the Omicron pandemic has not been established. The recent outbreak in China caused predominantly by the BA.5.2 and BF.7 strains of Omicron provided …

cn (code pays fourni par la source)

Additional file 2 of Association of gut microbiota with idiopathic membranous nephropathy

Mengfei Li, Lixue Wei, Jing Sun, Qianshen Zhu et autres

Additional file 2: Supplemental Table 2. α-Diversity was assessed with 4 different diversity analysis methods.

cn, sg, ca, kr, gb, us (code pays fourni par la source)

Additional file 1 of Association of gut microbiota with idiopathic membranous nephropathy

Mengfei Li, Lixue Wei, Jing Sun, Qianshen Zhu et autres

Additional file 1: Supplemental Table 1. Baseline characteristics of participants.

cn, sg, ca, kr, gb, us (code pays fourni par la source)