Xiaobai Liu

KHDRBS1 regulates the pentose phosphate pathway and malignancy of GBM through SNORD51-mediated polyadenylation of ZBED6 pre-mRNA

Xiaoyu Liu, Xiaobai Liu, Weiwei Dong, Ping Wang et autres

Glioblastoma is one of the most common and aggressive primary brain tumors. The aberration of metabolism is the important character of GBM cells and is tightly related to the malignancy of GBM. We mainly verified the regulatory effects of KHDRBS1, SNORD51 and …

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Association between dietary selenium intake and severe abdominal aortic calcification in the United States: a cross-sectional study

Weiwei Dong, Xiaobai Liu, Lu Ma, Zhiyong Yang

Abdominal aortic calcification (AAC) is an important predictor of cardiovascular disease. The purpose of the current study was to detect the association between dietary selenium intake and severe AAC. We included 2651 participants from the National Health and Nutrition Examination Survey (NHANES, …

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m5C modification of LINC00324 promotes angiogenesis in glioma through CBX3/VEGFR2 pathway

Aini Pan, Yixue Xue, Xuelei Ruan, Weiwei Dong et autres

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RBMS3-induced circHECTD1 encoded a novel protein to suppress the vasculogenic mimicry formation in glioblastoma multiforme

Xuelei Ruan, Yunhui Liu, Ping Wang, Libo Liu et autres

Glioblastoma multiforme (GBM) is a highly vascularized malignant cancer of the central nervous system, and the presence of vasculogenic mimicry (VM) severely limits the effectiveness of anti-vascular therapy. In this study, we identified downregulated circHECTD1, which acted as a key VM-suppressed factor …

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U3 snoRNA ‐mediated degradation of ZBTB7A regulates aerobic glycolysis in isocitrate dehydrogenase 1 wild‐type glioblastoma cells

Weiwei Dong, Yunhui Liu, Ping Wang, Xuelei Ruan et autres

Abstract Aims The isocitrate dehydrogenase (IDH) phenotype is associated with reprogrammed energy metabolism in glioblastoma (GBM) cells. Small nucleolar RNAs (snoRNAs) are known to exert an important regulatory role in the energy metabolism of tumor cells. The purpose of this study was …

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The mechanism of BUD13 m6A methylation mediated MBNL1-phosphorylation by CDK12 regulating the vasculogenic mimicry in glioblastoma cells

Meichen Liu, Xuelei Ruan, Xiaobai Liu, Weiwei Dong et autres

Vasculogenic mimicry (VM) is an endothelium-independent tumor microcirculation that provides adequate blood supply for tumor growth. The presence of VM greatly hinders the treatment of glioblastoma (GBM) with anti-angiogenic drugs. Therefore, targeting VM formation may be a feasible therapeutic strategy for GBM. …

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Retraction Note to: Linc00152 promotes malignant progression of glioma stem cells by regulating miR-103a-3p/FEZF1/CDC25A pathway

Mingjun Yu, Yixue Xue, Jian Zheng, Xiaobai Liu et autres

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The MBNL1/circNTRK2/PAX5 pathway regulates aerobic glycolysis in glioblastoma cells by encoding a novel protein NTRK2-243aa

Yubo Zhao, Jian Song, Weiwei Dong, Xiaobai Liu et autres

Glioblastoma multiforme (GBM) is the most common tumor of the human central nervous system. Aerobic glycolysis has been strongly related to tumor development and malignant behavior. In this study, we found that MBNL1, circNTRK2, and NTRK2-243aa were markedly downregulated and inhibited glycolysis …

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CPEB2 m6A methylation regulates blood–tumor barrier permeability by regulating splicing factor SRSF5 stability

Mengyang Zhang, Chunqing Yang, Xuelei Ruan, Xiaobai Liu et autres

The blood-tumor barrier (BTB) contributes to poor therapeutic efficacy by limiting drug uptake; therefore, elevating BTB permeability is essential for glioma treatment. Here, we prepared astrocyte microvascular endothelial cells (ECs) and glioma microvascular ECs (GECs) as in vitro blood-brain barrier (BBB) and …

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Retraction Notice to: Knockdown of USF1 Inhibits the Vasculogenic Mimicry of Glioma Cells via Stimulating SNHG16/miR-212-3p and linc00667/miR-429 Axis

Di Wang, Jian Zheng, Xiaobai Liu, Yixue Xue et autres

(Molecular Therapy: Nucleic Acids 14, 465–482; March 2019) This article has been retracted at the request of the editors. Molecular Therapy – Nucleic Acids is retracting this article. After investigating concerns of image duplication raised by a reader, the editors identified evidence …

A novel protein encoded by ZCRB1-induced circHEATR5B suppresses aerobic glycolysis of GBM through phosphorylation of JMJD5

Jian Song, Jian Zheng, Xiaobai Liu, Weiwei Dong et autres

BACKGROUND: RNA-binding proteins (RBPs) and circular RNAs (circRNAs) play important roles in glioblastoma multiforme (GBM). Aerobic glycolysis is a metabolic characteristic of GBM. However, the roles of RBPs and circRNAs in aerobic glycolysis in GBM remain unclear. The aim of this study …

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[Corrigendum] SNHG15 affects the growth of glioma microvascular endothelial cells by negatively regulating miR‑153

Yawen Ma, Yixue Xue, Xiaobai Liu, Chengbin Qu et autres

Following the publication of this article, the authors have realized that they had inadvertently used the same western blotting data to show the GAPDH control western blots in Figs. 1C and 4D. In examining their original data, the authors realized that the …

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