Swati Arora

Validation of Urinary C-C Motif Chemokine Ligand 14 for Persistent Severe AKI Using Clinical Adjudication

J. Patrick Kampf, Ali Al- Khafaji, Swati Arora, Anahat Dhillon et autres

BACKGROUND: Urinary C-C motif chemokine ligand 14 (CCL14) has been demonstrated to prognosticate persistent severe acute kidney injury (PS-AKI) in patients with established AKI. We sought to validate the performance of CCL14 among intensive care unit (ICU) patients, at previously established cutoffs …

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Glomerular frontiers: consensus perspectives from GlomCon Hawaii 2025

Niloufar Ebrahimi, Ali Poyan Mehr, Haresh Selvaskandan, Harish Seethapathy et autres

This review synthesizes the key scientific discussions and clinical insights presented at the Core Conference of GlomCon Hawaii 2025, held in Oahu, Hawaii, from September 23–25, 2025.

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Clinical Remission as a Function of Exposure to Cyclophosphamide in Patients with Primary Membranous Nephropathy: A One-Year Cohort Study

Swati Arora, Jorge Enrique Rojas-Rivera, Madeline S. Chung, Himanshu Patel et autres

Introduction: Primary membranous nephropathy (pMN) is a leading cause of nephrotic syndrome (NS) in adults. Cyclophosphamide (CYC) with glucocorticoids (GCs) is recommended for high and very high-risk patients, but the optimal treatment duration and cumulative dose remain unclear. This study aimed to …

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Towards an Interdisciplinary Consensus Definition of "Refractory Lupus Nephritis": A Kickoff Survey

Hans‐Joachim Anders, Julia Lichtnekert, Swati Arora, Melissa Sofia Grigorescu Vlass et autres

Background: There is no consensus for the definition of “Refractory Lupus Nephritis (RLN)”, which leads to confusion and overuse of this term for patients not responding to immunotherapy as expected. However, definition criteria, time of assessment and how to exclude drug non-adherence …

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Simultaneous Islet-Kidney Transplantation as an Alternative for Patients Ineligible for Pancreas Transplant: Initial Experience at a North American Transplant Center

Celine Parmentier, Abdulaziz Bakhsh, PRABUDH RAM MISRA, José Manuel et autres

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Weight-Based Sliding Scale vs. Fixed-Dose Loop Diuretics for Fluid Overload in CKD: A Retrospective Analysis

Sameen Aamer, Katelin Gardonis, Andrey Vavrenyuk, Randa Abd Algayoum et autres

Background: Managing fluid overload in chronic kidney disease (CKD) patients is challenging. Fixed doses of loop diuretics often lead to complications such as frequent hospitalizations due to volume overload or pre-renal acute kidney injury (AKI). While weight-based loop diuretic adjustments have reduced …

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Long-Term Outcomes of Patients with FSGS: A Multicenter Real-World Evidence (RWE) Study

Ali Poyan-Mehr, Alice J. Drozd, Tingting Li, Raymond K. Hsu et autres

Background: FSGS is a common histopathologic lesion in adult patients with nephrotic syndrome.We report on one of the most extensive observational studies of FSGS to identify predictors of long-term outcomes. Methods: Nine centers enrolled 723 patients with FSGS of primary, genetic, or …

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Vascular threads and nephron nests: exploring the association between Takayasu arteritis and membranous nephropathy

Sameen Aamer, Anand Rajan, Swati Arora

Takayasu arteritis (TA) primarily causes ischaemic nephrosclerosis but can occasionally be associated with glomerulopathy. We report a case of a female in her twenties with PLA2-negative, THSD7A-positive membranous nephropathy (MN) refractory to rituximab, who presented with neck pain and new-onset hypertension. Blood …

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A Comprehensive and Practical Approach to the Management of Lupus Nephritis in the Current Era

Nasim Wiegley, Swati Arora, Sayna Norouzi, Brad H. Rovin

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The Natural History of Focal and Segmental Glomerulosclerosis (FSGS)

Ali Poyan-Mehr, Tingting Li, Raymond K. Hsu, Tripti Singh et autres

Background: FSGS is the tissue manifestation of various kidney diseases that ultimately lead to end-stage kidney disease in most patients. Their rare and heterogeneous presentations and unpredictable responses to therapies pose a tremendous challenge. Here we report on one of the most …

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Membranoproliferative Glomerulonephritis (MPGN) in the Setting of Unicentric Castleman Disease

Ali W. Rizvi, Dale M. Kobrin, Naman Gupta, Michael Turk et autres

Introduction: Castleman’s disease (CD) is a rare lymphoproliferative disorder with histopathological abnormalities - divided primarily into unicentric and multicentric disease. Thought to be an inflammatory process, renal involvement has been described extensively in the setting of multicentric disease, especially associated with HHV-8. …

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To Study the Pattern of Histopathological Findings in Cases of Medicolegal Autopsies

Shiffali Sarngal, Swati Arora, Shveta Sharma, Shivani Jatin Gandhi

BACKGROUND Medicolegal autopsy is an important procedure to ascertain the causes of sudden and unexplained deaths. It provides direct access to organ and tissues which otherwise is not possible with other diagnostic modalities. In addition to the morphological examination of tissues and …

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