Mingqian Li

Shuangpi formula treats neutrophilic asthma via circadian-mediated anti-inflammatory mechanisms

Shasha Kong, Zhao Yang, Lixia Hao, Siqi Ji et autres

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Heterogeneity in adverse events associated with lumateperone: a study on potential subgroup-specific differences

Cheng Jiang, Luhan Tang, Mingqian Li, Guoqin Xia

BACKGROUND: Lumateperone, a novel atypical antipsychotic, has emerged as an illuminating hope for patients with schizophrenia and bipolar disorder. While prior studies have employed spontaneous reporting databases and identified over 100 novel adverse events associated with lumateperone, the differences in these adverse …

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Isolation and identification of anti-inflammatory diterpenoids from the post-distillation arils of Torreya grandis

Jing Tang, Shijie Zhan, Shubao Tu, Xiaoyan Hu et autres

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Sciadonic Acid Ameliorates Cognitive Impairment in APP/PS1 Mice with Concomitant Modulation of Gut Microbiota and Brain Metabolism

Shujuan Xie, Bo Zheng, Mingqian Li, Bin Zheng et autres

Alzheimer's disease (AD) is a progressive neurodegenerative disorder with complex pathogenesis. Sciadonic acid (SCA), a fatty acid from Torreya grandis oil, possesses antiinflammatory and antioxidant properties, but its effects on...

Icariin modulates the tumor microenvironment in colorectal cancer by targeting M2 macrophage polarization via PI3K/AKT pathway

Yu Chen, Yue Qi, Yulan Jiang, Ying Li et autres

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Corrigendum to “Isopimaric acid, an ion channel regulator, regulates calcium and oxidative phosphorylation pathways to inhibit breast cancer proliferation and metastasis” [Toxicology and applied Pharmacology, 2023, 462:116415]

Jiacheng Li, Xiaozhen Liu, Lin Chen, Xinping Zhu et autres

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Calcium channels as pharmacological targets for cancer therapy

Xiaozhen Liu, Changyun Feng, Yan Li, Jili Cao et autres

Ca 2+ , as critical second messengers in biological processes, plays a pivotal role in the regulation of diverse cellular signaling pathways. The dysregulation of calcium signaling is intricately linked to the progression of various cancers. The capacity of Ca 2+ to …

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The anti-tumor effects of main component (benzethonium chloride) of butorphanol tartrate injection in non-small cell lung cancer

Honglei Tao, Lei Li, Huiling Li, Tingting Ma et autres

Cancer is one of the leading causes of morbidity and mortality in the global population. The effective management of cancer-associated pain and anesthesia are critical aspects of comprehensive cancer treatment. However, the role and mechanism of anesthesia and analgesia-related drugs in tumors …

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Spatio-Temporal Dynamics of Carbon Storage in Rapidly Urbanizing Shenzhen, China: Insights and Predictions

Chunxiao Wang, Mingqian Li, Xuefei Wang, Mengting Deng et autres

Rapid urbanization in developing countries leads to significant land-use and land-cover change (LULCC), which contributes to increased carbon dioxide (CO2) emissions and the degradation of carbon storage. Studying spatio-temporal changes in carbon storage is crucial for guiding sustainable urban development toward carbon …

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Corrigendum to ''Spinosad blocks CHRNA5 mediated EGFR signaling pathway activation to inhibit lung adenocarcinoma proliferation'' [Biomed. Pharma. 177 (2024) 117105]

Hongling Zou, Yan Chen, Xinping Zhu, Xinyun Zhao et autres

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Liquidambaric acid inhibits the proliferation of hepatocellular carcinoma cells by targeting PPARα-RXRα to down-regulate fatty acid metabolism

Xinyun Zhao, Xinping Zhu, Honglei Tao, Hongling Zou et autres

Hepatocellular carcinoma (HCC) is a primary malignant tumor of the liver. As the global obesity rate rises, non-alcoholic fatty liver disease (NAFLD) has emerged as the most rapidly increasing cause of HCC. Consequently, the regulation of lipid metabolism has become a crucial …

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STS MICCAI 2023 Challenge: Grand challenge on 2D and 3D semi-supervised tooth segmentation

Yaqi Wang, Yifan Zhang, Xiao-Diao Chen, Shuai Wang et autres

Computer-aided design (CAD) tools are increasingly popular in modern dental practice, particularly for treatment planning or comprehensive prognosis evaluation. In particular, the 2D panoramic X-ray image efficiently detects invisible caries, impacted teeth and supernumerary teeth in children, while the 3D dental cone …