Xinhuan Zhang

A systematic review and meta-analysis of microRNAs in the diagnosis of early diabetic kidney disease

Li Li, Ke Zhang, Liping Zheng, Xinhuan Zhang et autres

Objective: The aim of this study was to comprehensively assess the overall diagnostic value of circulating microRNAs (miRNAs or miRs) as biomarkers for the early diagnosis of diabetic kidney disease (DKD) through Meta-analysis, and to identify potential molecular biomarkers with higher diagnostic …

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Centralization or Equalization? Policy Trend Guidance for Improving Grain Production Security in China

Rongqian Lu, Xinhuan Zhang, Degang Yang, Yang Chen et autres

Global grain production faces severe risks and challenges, such as the complex and volatile international situation and the frequent occurrence of extreme weather events. The effectiveness of national policies intended to support grain production security is becoming increasingly important. China has implemented …

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Intensive Blood-Pressure Control in Patients with Type 2 Diabetes

Yufang Bi, Mian Li, Tianlong Li, Jieli Lu et autres

BACKGROUND: Effective targets for systolic blood-pressure control in patients with type 2 diabetes are unclear. METHODS: We enrolled patients 50 years of age or older with type 2 diabetes, elevated systolic blood pressure, and an increased risk of cardiovascular disease at 145 …

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Identification of key anoikis-related genes and immune cell infiltration characteristics in T2DM based on integrating bioinformatic analysis and machine learning

Ke K. Zhang, Wenwen Lu, Xinyuan Tang, Xinhuan Zhang

Background: The increasing incidence of type 2 diabetes mellitus (T2DM) is a serious threat to human health and poses a significant global economic burden. Anoikis is a special type of apoptosis. There is growing evidence that anoikis plays a key role in …

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A meta-analysis of the therapeutic effect of probiotic intervention in obese or overweight adolescents

Yuanqing Duan, Yan Ma, Lei Ning, Xinhuan Zhang

Background & aims Existing evidence on the possible effects of probiotics on obese or overweight adolescents has not been fully established. Therefore, the aim of this study was to explore the effects of probiotic supplementation on anthropometric indices, inflammatory markers and metabolic …

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A Meta-Analysis of the Therapeutic Effect of Probiotic Intervention in Obese or Overweight Adolescents

Yuanqing Duan, Yan Ma, Lei Ning, Xinhuan Zhang

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A commentary on ‘Preoperative carbohydrate loading with individualized supplemental insulin in diabetic patients undergoing gastrointestinal surgery: a randomized trial’

Hanwen Cao, Ke Zhang, Mingfeng Cao, Xinhuan Zhang

aShandong First Medical University&Shandong Academy of Medical Science, Shandong, 271000, China bDepartment of Endocrinology, the Second Affiliated Hospital of Shandong First Medical University, Shandong, 271000, China Fund program: Higher Educational Science and Technology Program of Shandong Province (J17KA246) Sponsorships or competing interests …

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Effects of Policy Intervention on Food System Resilience to Emergency Risk Shock: Experience from China during COVID-19 Pandemic

Mingjie Cui, Xinhuan Zhang, Yufang Zhang, Degang Yang et autres

Achieving the goal of zero hunger within the goal of sustainable development requires improving the resilience of food systems to various types of risk shocks; food systems have shown significant vulnerability to COVID-19 outbreaks and transmission. By analyzing the impact of China's …

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Study on the Spatial Differentiation Characteristics and Influencing Factors of China’s Economic Resilience under Different Shocks

Tao Zhao, Jinwei Huo, Degang Yang, Xinhuan Zhang et autres

Recognizing regional economic resilience and its influencing factors under different shocks is necessary to promote stable regional economic development. The article analyzes the regional economic resilience of 31 Chinese provinces under three kinds of shocks, namely, financial crisis, economic downturn, and COVID-19, …

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Bioinformatics analysis identifies immune-related gene signatures and subtypes in diabetic nephropathy

Kunna Lu, Li Wang, Yan Hong Huang Fu, Guanghong Li et autres

Background: Systemic inflammation and immune response are involved in the pathogenesis of diabetic nephropathy (DN). However, the specific immune-associated signature during DN development is unclear. Our study aimed to reveal the roles of immune-related genes during DN progression. Methods: The GSE30529 and …

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Effect of a high vs. standard dose of vitamin D3 supplementation on bone metabolism and kidney function in children with chronic kidney disease

Zhiqiang Feng, Kunna Lu, Yan Ma, Feng Liu et autres

We investigated the effects of high- vs. standard-dose vitamin D supplementation on kidney function and bone metabolism in children with chronic kidney disease (CKD). Children were randomized to receive one of two formulations: 75 participants received 2,000 IU/D of oral supplementation of …

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Effect of Higher vs Standard Dosage of Vitamin D3 Supplementation on Bone Strength and bone metabolism in child with chronic kidney disease

Zhiqiang Feng, Kunna Lu, yan ma, Feng Liu et autres

Abstract We investigated the effects of high VS. standard dose of vitamin D supplementation on kidney function and bone metabolism in children with chronic kidney disease (CKD). In all, 75 participants receive 2000 IU/D of vitamin D oral supplementation vs 75 participants …

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