Yufang Zhang

Association between serum trimethylamine N-oxide levels and sleep quality in mid-pregnancy women in Guangzhou: The mediating role of hematological inflammatory markers

Jie Li, Jieying Peng, Xiao Yu, Siyao Zhou et autres

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Prediction of Unsteady Aerodynamic Load on Centrifugal Compressor Impeller Based on Parameterized Models

Yufang Zhang, Shuai Li, Youhua Li, Hechun Yu et autres

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Study on the mechanical characteristics and anchorage performance of the anchor cable with precast internal-anchor-head (PIAC)

Bo Liu, Yufang Zhang, Kun Yuan, Jian Li et autres

Abstract In order to improve the anchoring force of traditional anchor cables while ensuring low cost, this paper proposed a new-type anchor cable structure with a precast internal-anchor-head (PIAH) at the anchor cable end. The reliability of the new structure was thoroughly …

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Kinetic characteristics investigation of the Yingxingping rockslide based on discrete element method combined with discrete fracture network

Bo Liu, Yufang Zhang, Xiewen Hu, Jian Li et autres

The development of rock fractures on the mountain ridge in meizoseismal area may lead to fatal rockslides. This study focused on a catastrophic post-earthquake rockslide case in Wenchuan, Southwestern China. On-site investigation and aerial photography were used to ascertained the basic characteristics …

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Mechanism of action of BMI1 in the induction of partial EMT in tongue squamous cell carcinoma to promote metastasis

Tianyue Huang, Yingluo Chen, Yanfei Wu, Jun Cheng et autres

OBJECTIVE: To investigate the regulatory role of stemness factor BMI1 in epithelial-mesenchymal transition (EMT) and metastasis of tongue squamous cell carcinoma (TSCC) METHODS: Clinical and mouse TSCC specimens were analyzed for BMI1/TGF-β1 expression via immunohistochemistry (IHC). In vitro studies used SCC-9 cells …

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Optimization Design of Anti-slide Pile Reinforcement for Bedding Slopes Using BP Neural Network and Genetic Algorithm

Shi Wang, Xinyu Wang, Yufang Zhang, Junjie Wang

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Intranasal Drug Delivery Technology in the Treatment of Central Nervous System Diseases: Challenges, Advances, and Future Research Directions

Xunxun Wu, Ranqing Zang, Yiting Qiu, Yufang Zhang et autres

As population aging becomes an increasingly critical global issue, the incidence of central nervous system (CNS) diseases, including Alzheimer's disease (AD), Parkinson's disease (PD), and stroke, has risen sharply. However, the blood-brain barrier (BBB) presents a significant obstacle to the effective treatment …

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Strand displacement‐driven CRISPR/Cas12a framework enables precise identification of low‐abundance point mutations

Jiaxi Mo, Yan Zhao, Chenyu Sun, Mingtao Li et autres

Abstract Accurate identification of low‐abundance point mutations is a crucial technical challenge in clinical diagnosis, particularly within high wild‐type genomic backgrounds. We established an engineered Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR‐associated 12a proteins (Cas12a) point mutation detection strategy (E‐CRISPR) …

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Strand Displacement-Driven CRISPR/Cas12a Framework Enables Precise Identification of Low-Abundance Point Mutations

Jiaxi Mo, Yan Zhao, Chenyu Sun, Mingtao Li et autres

Accurate identification of low-abundance point mutations is a crucial technical challenge in clinical diagnosis, particularly within high wild-type genomic backgrounds. We established an engineered CRISPR/Cas12a point mutation detection strategy (E-CRISPR) for low-abundance point mutations detection. By integrating the precise regulatory mechanism of …

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Research on the Effect of the Impeller-Diffuser Radial Clearance in a Centrifugal Compressor Stage with a Large Flow Coefficient using Proper Orthogonal Decomposition Method

Yufang Zhang, Shuai Li

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Experimental study on the bearing capacity and effective anchorage lengths of inclined steel grouting pipes in loess embankment slope

Yufang Zhang, Kun Yuan, Wenjiao Zhou

Splitting grouting is widely used to reinforce unfavorable soil stratum. Inclined steel grouting pipe is a type of structure which can achieve splitting grouting in soil stratum. It has been successfully utilized in argillaceous sandstone stratum, but its application in loess stratum …

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Assessment and Prediction of the Food Production Capacity and Consumption Gap in Arid Oasis Metropolitan Area

Mingjie Cui, Yufang Zhang, Degang Yang, Wenqiang Xu et autres

Food security is the foundation of sustainable human development, and the balance between food supply and demand in urban areas is highly important for promoting residents' health and the sustainable development of cities. This paper takes the Urumqi Metropolitan Area (UMA), a …

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