Hongxia Shao

A Naturally Occurring Novel Reassortant Strain of Infectious Bursal Disease Virus from Quails

Pengyu Guo, Xinyao Guo, 余春, Wei Gao et autres

Infectious bursal disease virus (IBDV) primarily triggers severe immunosuppression in birds and has resulted in substantial economic losses to the poultry industry globally. Here, a novel naturally reassortant IBDV strain, designated IBDV_G3, was isolated from quails during a disease outbreak in Jiangsu …

cn (code pays fourni par la source)

Study on the Construction of Immersive Learning Scene in the Construction of “Integration of Large, Medium and Small” Civics Course Based on Virtual Reality Technology

Hongxia Shao

The improvement of the integrated construction of ideological and political education promotes the equitable development of education. To enhance the realism and construction efficiency of immersive learning scenarios, this paper proposes an improved registration algorithm (RANSAC) based on the determinant point process …

cn (code pays fourni par la source)

A novel recombinant serotype 4 fowl adenovirus efficiently protects both serotype 4 and 11 fowl adenovirus

Shi Liu, Ye Tang, Tuofan Li, Zhimin Wan et autres

cn (code pays fourni par la source)

Q221K mutation in VP2 drives antigenic shift of infectious bursal disease virus

Haifeng Xiong, Jiayan Wu, Quan Xie, Tuofan Li et autres

Introduction: Infectious bursal disease (IBD) is a severe immunosuppressive disease caused by the infection of infectious bursal disease virus (IBDV) in chicken. Recently, an emerging mutant named novel variant IBDV (nVarIBDV) has rapidly spread in China and become a prevalent strain. However, …

mv, cn (code pays fourni par la source)

Research on the construction strategy of “integration of large, medium and small” in the ideology course in the context of the new era

Hongxia Shao

Abstract The “integration of large, medium and small” of the ideology and politics course is an ideological and political education project that should meet the requirements of the development of the present era. In the context of the new era, the study …

cn (code pays fourni par la source)

Protective Efficacy of an Inactivated Recombinant Serotype 4 Fowl Adenovirus Against Duck Adenovirus 3 in Muscovy Duck

Yun Lin, Wenjie Jiang, Lihua Ma, Ye Tang et autres

BACKGROUND: Duck adenovirus 3 (DAdV-3) is an emerging pathogen that has caused severe economic losses to the duck industry in China. Recently, the infection of ducks with serotype 4 fowl adenovirus (FAdV-4) has also been reported in China. Therefore, an efficient bivalent …

cn (code pays fourni par la source)

Punicalagin Inhibits African Swine Fever Virus Replication by Targeting Early Viral Stages and Modulating Inflammatory Pathways

Renhao Geng, Dan Yin, Yingnan Liu, Hui Lv et autres

African swine fever (ASF), caused by the African swine fever virus (ASFV), has resulted in significant losses in the global pig industry. Considering the absence of effective vaccines, developing drugs against ASFV may be a crucial strategy for its prevention and control …

cn (code pays fourni par la source)

Aloperine Inhibits ASFV via Regulating PRLR/JAK2 Signaling Pathway In Vitro

Renhao Geng, Hongxia Shao, Kun Qian, Hongjun Chen et autres

African swine fever (ASF) has become a global pandemic due to inadequate prevention and control measures, posing a significant threat to the swine industry. Despite the approval of a single vaccine in Vietnam, no antiviral drugs against the ASF virus (ASFV) are …

cn (code pays fourni par la source)

Molecular epidemiology of infectious bronchitis virus in eastern and southern China during 2021–2023

Xian-Chen Meng, Jianjun Zhang, Zhimin Wan, Tuofan Li et autres

As a highly infectious and contagious pathogen in chickens, infectious bronchitis virus (IBV) is currently grouped into nine genotypes (GI to GIX). However, the classification of serotypes of IBV is still not clear. In this study, 270 field strains of IBV were …

cn (code pays fourni par la source)

Long-Term Protection against Virulent Newcastle Disease Virus (NDV) in Chickens Immunized with a Single Dose of Recombinant Turkey Herpesvirus Expressing NDV F Protein

Bin Shi, Guifu Yang, Yue Xiao, Kun Qian et autres

Newcastle disease (ND) is a significant infectious disease in poultry, causing substantial economic losses in developing countries. To control ND, chickens must be vaccinated multiple times a year. In order to develop an improved vaccine that provides long-term protection, the F gene …

cn (code pays fourni par la source)

Chicken Glycogen Synthase Kinase 3β Suppresses Innate Immune Responses and Enhances Avian Leukosis Virus Replication in DF-1 Cells

Zhouhao Cui, Bei Weng, Yongxiu Yao, Hongxia Shao et autres

GSK3β regulates many life activities in mammals. Recent studies revealed that chGSK3β was involved in regulating antiviral innate immunity in DF-1 cells and also could positively regulate ALV-J replication. These results provide new insights into the biofunction of chGSK3β and the virus-host …

cn, gb (code pays fourni par la source)

A novel mAb broadly neutralizes SARS‐CoV‐2 VOCs in vitro and in vivo, including the Omicron variants

Qiuqi Kan, Xian Zhi Lin, Tuofan Li, Xianliang Ke et autres

Abstract Novel immune escape variants have emerged as severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) continues to spread worldwide. Many of the variants cause breakthrough infections in vaccinated populations, posing great challenges to current antiviral strategies targeting the immunodominance of the receptor‐binding …

cn (code pays fourni par la source)