Fang Chen

Screening telomere-related genes to predict prognosis, immunotherapy response, and drug sensitivity in esophageal cancer using a machine learning approach

Shuang Li, Fang Chen, Tao Zheng, Wei Jiang et autres

BACKGROUND: Esophageal cancer (EC) is a common malignancy with poor prognosis. Telomeres, composed of repetitive DNA sequences and shelterin complexes, play important roles in tumor biology. However, the prognostic value of telomere-related genes (TRGs) in EC remains unclear. METHODS: TRGs were obtained …

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Free Fetal Haemoglobin in Fetal Growth Restriction

Fang Chen, Dong‐Zhi Li

This study did not generate new data sets, nor did it use existing data sets. Fang Chen. Dong-Zhi Li.

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Reply: Free Fetal Hemoglobin in Severe Early-Onset Fetal Growth Restriction

Fang Chen, Dong‐Zhi Li

Normally, nearly all hemoglobin is contained within circulating red blood cells.Circulating free hemoglobin is not detectable in significant quantities in adults.Several pathways have been identified for the rapid scavenging and removal of free hemoglobin from circulation, including the plasma proteins haptoglobin and …

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A nomogram for postoperative pulmonary infections in esophageal cancer patients: a two-center retrospective clinical study

Shuang Li, Fang Chen, Tao Zheng, Jingfeng Zhu et autres

BACKGROUND: Postoperative pulmonary infections (POPIs) occur in approximately 13-38% of patients who undergo surgery for esophageal cancer, negatively impacting patient outcomes and prolonging hospital stays. This study aims to develop a novel clinical prediction model to identify patients at risk for POPIs …

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An Informatics Framework for Accelerating Digital Health Technology Enabled Randomized Controlled Trial Candidate Guideline Item Development

Di Hu, Heling Jia, Shyang Hong Tan, Fang Chen et autres

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Spatiotemporal characteristics and Monte Carlo simulation-based human health risk of heavy metals in soils from a typical coal-mining city in eastern China

Xiangyue Pan, Xinrui Weng, Lingyu Zhang, Fang Chen et autres

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Achondrogenesis type 1B: The need for clinical vigilance in the first trimester fetus with cystic hygroma and micromelic limbs

Fang Chen, Dongzhi Li

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Cervical Balloon Induction in LDRP Unit: Effects on Maternal and Neonatal Outcomes for Primiparous Women

Chunfeng Gao, Qiang Ma, Jinhua Dong, Fang Chen et autres

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Comparative growth, biochemical and sensory analyses reveal the feasibility of large-scale development of selenium-enriched Tartary buckwheat sprouts

Manh Hung NGUYEN, Hanlei Xiao, Xin TAN, Fang Chen et autres

Selenium is an essential trace element in the human diet and has anti-aging, anti-tumor, and immunity boosting effects. In this study, the effects of selenium on Tartary buckwheat (Fagopyrum tataricum L.) sprouts were investigated. A suitable concentration of selenium had no adverse …

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RETRACTED: Adverse Pregnancy Outcomes Following Exposure to Biologics in Women With Crohn's Disease: A Systematic Review and Meta-Analysis

Han Wang, Fang Chen, Yue Hu, Mengdie Shen

Crohn's disease is a chronic disease, which commonly affects women during their reproductive years. Poorly treated Crohn's disease is associated with adverse pregnancy outcomes. Biologics, a group of therapeutic drugs targeting inflammatory mediators including anti-TNF, anti-integrins and anti-interleukins, are increasingly used in …

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Epidemiological and clinical features of SARS-CoV-2 cluster infection in Anhui Province, Eastern China

Jiabing Wu, Xiuzhi Chen, Lei Gong, Shaohu Huo et autres

BACKGROUND: COVID-19 has spread worldwide and become a pandemic. We report the epidemiological and clinical characteristics of cluster infections. METHODS: Data of clustered cases were retrieved from the public health emergency monitoring information system of China. We analyzed the incubation period, generation …

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Genomic epidemiology of SARS-CoV-2 in the United Arab Emirates reveals novel virus mutation, patterns of co-infection and tissue specific host innate immune response

Rong Liu, Pei Wu, Pauline Ogrodzki, Sally Mahmoud et autres

Abstract To unravel the source of SARS-CoV-2 introduction and the pattern of its spreading and evolution in the United Arab Emirates, we conducted meta-transcriptome sequencing of 1,067 nasopharyngeal swab samples collected between May 9th and Jun 29th, 2020 during the first peak …

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