Nan Xie

Tumor Budding Is a Promising Indicator for Elective Neck Dissection in Node‐Negative Early‐Stage Oral Squamous Cell Carcinoma: A Retrospective Cohort Study

Bokai Yun, Wenjin Wang, Gan Xiong, Yi Chen et autres

ABSTRACT Background The optimal management of early‐stage oral squamous cell carcinoma (OSCC) with clinically node‐negative neck remains controversial. A reliable biomarker to stratify occult metastasis risk for elective neck dissection (END) is lacking. Methods This retrospective cohort included 231 early‐stage cN0 OSCC …

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Predicting survival in oral squamous cell carcinoma via integrated analysis of tumor budding and tertiary lymphoid structures

Zhuqin Xiang, Yaqi Huang, Bokai Yun, Dongpeng Li et autres

Background: Oral squamous cell carcinoma (OSCC) poses a significant health burden. Accumulating evidence indicates that tumor budding (TB) and tertiary lymphoid structures (TLS) are both associated with the survival prognosis of OSCC patients; however, the prognostic value of integrated TB and TLS …

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Clinicopathological and prognostic implications of OPMDs in oral squamous cell carcinoma: a 17-Year retrospective cohort study

Jinmei Wang, Zihang Ling, Jingyi Lu, Nan Xie et autres

OBJECTIVES: To characterize the clinicopathologic features of patients with oral squamous cell carcinoma (OSCC) and evaluate the prognostic significance of the history of oral potentially malignant disorders (OPMDs) in this population. MATERIALS AND METHODS: This retrospective, single-center study enrolled 1140 patients from …

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A rare case of peripheral ameloblastic fibroma manifesting as a maxillary gingival mass

Yu Du, Ping Yang, Nan Xie, Ning Yang

BACKGROUND: Ameloblastic fibroma (AF) is a rare benign odontogenic tumor characterized by the coexistence of epithelial and mesenchymal components, typically arising intraosseously in the posterior mandible during the first two decades of life. Its peripheral variant, occurring extraosseously in gingival soft tissue …

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Somatization symptoms and burnout: a correlational study among emergency nurses

Na Li, Nan Xie, Xiaoli Chen, Hao Zhang et autres

Background Somatic symptom disorder is influenced by various factors, with increasing evidence highlighting its close association with burnout. This study aimed to investigate the correlation between somatization symptoms and burnout levels among emergency nurses, focusing on the impact of burnout on somatization. …

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Association between workplace violence and occupational stress among emergency department nurses: a cross-sectional study

Long Li, Nan Xie, Xiaoli Chen, Hao Zhang et autres

Background: Emergency department (ED) nurses suffer from workplace violence (WPV) and occupational stress (OS) due to the working environment. However, a relatively small number of studies on the relationship between WPV and OS among ED nurses have been conducted and its impact …

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Unmasking Hidden High-Risk Neuroblastoma: ML-Driven CMBs Refine Conventional Risk Stratification –Two case reports

Pan Sirui, Xu Wang, Jianfeng Zhou, Qiyang Shen et autres

Background Neuroblastoma (NB) is the most frequent solid cancer of early childhood. Owing to the significant heterogeneity of NB, which results in variation in treatment response and outcomes, the International Neuroblastoma Risk Group (INRG) and Children’s Oncology Group (COG) staging systems have …

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Development of a Novel Multi‐Epitope Vaccine Against Streptococcus anginosus Infection via Reverse Vaccinology Approach

Li Xu, Nan Xie, Yiqing Liu, Hongmei Tang et autres

Streptococcus anginosus is an opportunistic pathogen known for its capability to cause a broad range of infections, posing a significant and growing global health concern. Alongside enhancing diagnostic capabilities and bolstering public health initiatives, developing a safe and effective vaccine represents a …

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Clinical and Genetic Characteristics of Pediatric Colorectal Cancer

Qiyang Shen, Yong Chun Zhou, Xingyu Liu, Jian Li et autres

BACKGROUND: Compared to colorectal cancer (CRC) in adults, CRC in children is extremely rare. Although its incidence has increased recently, there is a lack of clinical research on the disease. Inherited cancer susceptibility syndromes (ICSS), a group of disorders in which patients …

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In Situ Ligand-Transformation-Assisted Assembly of a Polyoxometalate and Silver-Phosphine Oxide Cluster for Colorimetric Detection of Phenol Contaminants

Junfang Yang, Yuan‐Yuan Ma, Nan Xie, Yu-Tao Tang et autres

In situ ligand transformation strategies represent an efficient pathway for constructing function-oriented polyoxometalate (POM)-based crystalline materials. Herein, three POM-based hybrid networks were synthesized through in situ transformation of the phosphine ligand, formulated as [Ag(dppeo) 6 ][H 2 PMo 12 O 40 ]·5H …

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CN95 A novel nomogram based on inflammation biomarkers for predicting radiation cystitis in patients with local advanced cervical cancer

Y. Sun, J. Lin, Lihui Liu, Nan Xie et autres

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Role of aryl hydrocarbon receptors in infection and inflammation

Linglan Xu, Luping Lin, Nan Xie, Weiwei Chen et autres

The aryl hydrocarbon receptor (AhR) is a transcription factor that is activated by various ligands, including pollutants, microorganisms, and metabolic substances. It is expressed extensively in pulmonary and intestinal epithelial cells, where it contributes to barrier defense. The expression of AhR is …

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