Yibo Chen

Retinoic acid is a translation inhibitor against chikungunya virus both in vitro and in vivo

Yibo Chen, Zhiwei He, Ke Zhang, Xijing Qian et autres

Chikungunya virus (CHIKV), a mosquito-borne alphavirus, causes debilitating febrile and arthritic disease and remains a persistent public health threat in tropical and subtropical regions, with no clinically approved antiviral drugs currently available, which underscores the urgent need for targeted and effective therapeutic …

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BenCao: An Instruction-Tuned Large Language Model for Traditional Chinese Medicine

Jiacheng Xie, Yang Yu, Yibo Chen, Hanyao Zhang et autres

Traditional Chinese Medicine (TCM), with a history spanning over two millennia, plays a role in global healthcare. However, applying large language models (LLMs) to TCM remains challenging due to its reliance on holistic reasoning, implicit logic, and multimodal diagnostic cues. Existing TCM-domain …

Influence of Pre‐Vaccination HPV Status on Vaccine Effectiveness Among Chinese Women: A Multicenter Cross‐Sectional Study

L. J. Li, Haiyue Wu, Yibo Chen, Kun Fu et autres

BACKGROUND AND AIMS: Human papillomavirus (HPV) vaccines have been available in China for only 8 years, and routine HPV testing is not recommended prior to vaccination. Therefore, evaluation of HPV vaccine effectiveness and the impact of pre-vaccination HPV infection status on vaccine …

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Neural-Network-Based Prediction of Non-Burial Overwintering Material Covering Height for Wine Grapes

Yunlong Ma, Jin‐Yue Yang, Yibo Chen, Ping Wang et autres

Grapevines in cold regions are prone to frost damage in winter. Due to its adverse effects on soil structure, plant damage, high operational costs, and limited mechanization feasibility, buried soil overwintering has been gradually replaced by no-burial overwintering techniques, which are now …

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Performance Evaluation of a Groundwater Source Heat Pump System Utilized in a Regional Energy Station in the Cold Region of China

Yibo Chen, Chen Xu, Yang Jianzhong, Guoyou Cui et autres

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Assessment of PAX1 and JAM3 methylation triage efficacy across HPV genotypes and age groups in high-risk HPV-positive women in China

Liang Hui, Yao Liu, Mengyu Jiang, Hanhan Wang et autres

Objective: methylation (CISCER) test in triaging high-risk human papillomavirus (hrHPV)-positive women. Methods: We enrolled women who underwent opportunistic screening at Cervical Disease outpatient clinics of Xuzhou Maternity and Child Health Hospital, and Yueyang Central Hospital from December 2022 to May 2024. The …

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Factors Influencing the Protective Effect of HPV vaccine in Chinese Women: A Multicenter Cross-Sectional Study

L. J. Li, Haiyue Wu, Yibo Chen, Kun Fu et autres

Background: HPV vaccines have only been used in China for 8 years, and routine HPV test is not recommended before HPV vaccination, there is still a need to figure out HPV effectiveness, and the impact of pre-vaccination HPV infection status on the …

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Primary breast myeloid sarcoma: A case report and literature review

Zhiying Zhang, Yibo Chen, Rui Zhang, Ming Liu

Myeloid sarcoma (MS) is a rare extramedullary tumor originating from immature bone marrow cells. MS of the breast is an extremely uncommon disease with non-specific clinical and radiological features. The present case report describes a distinctive case of MS of the breast, …

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Phosphatidylcholine Transfer Protein OsPCTP Interacts with Ascorbate Peroxidase OsAPX8 to Regulate Bacterial Blight Resistance in Rice

Rong Gong, Huasheng Cao, Yangyang Pan, Wei Liu et autres

Rice phosphatidylcholine transfer protein (PCTP), which contains a steroidogenic acute regulatory protein-related lipid transfer (START) domain, responds to bacterial blight disease. Overexpression of OsPCTP quantitatively enhances resistance to pathogen in rice, whereas depletion of it has the opposite effect. Further analysis showed …

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Auditory Spatial Attention Detection Based on Feature Disentanglement and Brain Connectivity-Informed Graph Neural Networks

Yixiang Niu, Ning Chen, Hongqing Zhu, Zhiying Zhu et autres

A 9.5-kb deletion in the 1st intron of OsMADS51 enhances temperature sensitivity in rice

Lei Zhao, Haifei Hu, Junyu Chen, Chongrong Wang et autres

Temperature is an important environmental factor affecting heading date of rice. Despite its importance, genes responsible for temperature-sensitive heading in rice have remained elusive. Our previous study identified a quantitative trait locus qHd1 which advances heading date under high temperatures. A 9.5-kb …

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Identifying behavioral links to neural dynamics of multifiber photometry recordings in a mouse social behavior network

Yibo Chen, Jonathan M. Chien, Bing Dai, Dayu Lin et autres

Abstract Objective. Distributed hypothalamic-midbrain neural circuits help orchestrate complex behavioral responses during social interactions. Given rapid advances in optical imaging, it is a fundamental question how population-averaged neural activity measured by multi-fiber photometry (MFP) for calcium fluorescence signals correlates with social behaviors …

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