Fangzhou Liu

Effect of Pore-Throat Structure and Displacement Fluid Type on Relative Permeability in Low-Permeability Sandstone Reservoirs

Jing Li, Fangzhou Liu, Mingxi Liu, Kaoping Song et autres

Low-permeability sandstone reservoirs are characterized by fine pore-throat structures and strong heterogeneity, leading to complex multiphase flow behavior; since relative permeability curves are highly sensitive to displacement media, they serve as critical parameters for EOR performance and development optimization, yet the coupling …

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Dynamic evolution of displacement patterns during thickened supercritical carbon dioxide flooding in heavy-oil reservoirs

Yu Zhang, Daigang Wang, Fangzhou Liu, Nanyu Ji et autres

During heavy-oil displacement by supercritical carbon dioxide (sc-CO2), the large viscosity contrast between sc-CO2 and heavy oil induces fingering instability and gas channeling. Thickened sc-CO2 improves mobility control and partly suppresses fingering; however, CO2 dissolution and diffusion still alter the oil-phase viscosity …

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Groundwater inundation calculation and prediction based on a groundwater connectivity domain algorithm

Jianjun Gan, Yanwen Xin, Chengyi Liu, Juanhua Gan et autres

Groundwater inundation prediction and simulation are important for water resource management and geological disaster prevention in plain areas. The inundation height and extent are two important indicators for evaluating reservoir inundation. Although inundation models based on groundwater seepage theory can be used …

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COX5A promotes cell progression and cisplatin‐resistance by alleviating mitochondrial dysfunction in head and neck squamous cell carcinoma

Nannan Guo, Zhangyu Yao, Bo Gui, Qingya Sun et autres

Abstract Mitochondrial metabolic reprogramming is a reason for the cisplatin‐resistant state of head and neck squamous cell carcinoma (HNSCC) and confers cisplatin resistance. The functions of cytochrome c oxidase subunit 5a (COX5A) and its target interferon‐stimulated gene 15 (ISG15) in modulating cellular …

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Doctor Sun: a bilingual multimodal large language model for biomedical AI

Dong Xue, Zhaoyang Duan, Fangzhou Liu, Bing Li et autres

While biomedical artificial intelligence (AI) shows great clinical potential, existing systems relying on general-domain large language models (LLMs) often lack sufficient medical data to grasp complex healthcare concepts. Furthermore, recent Large Language and Vision Assistant (LLaVA)-based medical multimodal large language models (MLLMs) …

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Numerical insights into rate-and-state frictional control of quasi-periodic stick–slip in granular fault gouge

Yafeng Chen, Guoqing Chen, Qiang Xu, Fangzhou Liu et autres

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Effect of steel slag contents on road performance of rubber-modified permeable asphalt mixtures

Shanshan Wang, Guangyong Wang, Fangzhou Liu, Zihao Zhang et autres

Based on laboratory test results, this study provides a comprehensive evaluation of the mechanical properties, durability, microstructural characteristics, and functional properties of steel slag rubber permeable asphalt mixtures with different steel slag contents, leading to the following conclusions: Incorporating steel slag into …

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Probabilistic TSF stability assessment using a NorSand-based random-field framework

Fangzhou Liu, Ekansh Agarwal

Tailings materials are inherently heterogeneous systems where deposition processes produce layering, segregation, and spatial variability in density and structure. Conventional analyses often neglect this spatial variability and instead rely on a single deterministic representation of in-situ state. This study presents a practical …

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Development of an Arduino-Based Flow Control System for Precision Rainfall Simulation and Its Application to Experimental Study on Seepage Failure of Braced Excavation in Sandy-Gravel Mixed Strata

Weizhen Jiang, Yong Tan, Fangzhou Liu

ABSTRACT Precise simulation of rainfall is crucial for physical modeling of rainfall-related geohazards and geotechnical failures. The practicality of conventional rainfall simulators was often compromised by several limitations, such as restricted real-time adjustability, significant cost, and a lack of versatility across different …

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Energy conversion of NPR protective net under high-energy impacts

Kuiming Liu, Fangzhou Liu, Manchao He, Chun Zhu et autres

The rapid expansion of infrastructure and transportation networks in the mountainous regions of Southwest China imposes significant challenges in mitigating rockfall-related geological hazards, posing threats to human life and engineering safety. In recent years, the frequency and intensity of high-energy rockfall hazards …

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Single-cell and bulk transcriptomics reveal Fusobacterium nucleatum promotes colorectal cancer metastasis by upregulating LAMC2 in in vitro and in vivo models

Songlin Ran, Jinhua Ye, Hufei Wang, Fangzhou Liu et autres

Colorectal cancer (CRC) is one of the most prevalent malignancies worldwide. Fusobacterium nucleatum (F. nucleatum) has been strongly implicated in CRC metastasis. However, the contribution of laminin γ2 chain (LAMC2) to F. nucleatum-induced CRC metastasis remains elusive. We investigated the role of …

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Data processing and analysis technology of power grid assets based on particle swarm optimization of random forest

Shuyi Pan, Ming Jing, Fangzhou Liu, Xiaohong Zhang et autres

Integrating big data with power grid cost control is key to improving efficiency and ensuring sustainability. As asset management precision grows, accurate classification and prediction of asset data has become a research focus. Traditional methods are limited by fixed parameters. This paper …

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