Xiaolin Zhang

Multiple Regulatory Mechanisms of Post-Translational Modifications and Therapeutic Potential of Mitotic Catastrophe

Q. Zhang, Xia Chen, Shikun Li, Liang-Zi Cao et autres

Mitotic catastrophe refers to a complicated mechanism of cell death characterized by failure to complete the processes of mitosis correctly due to aberrant chromosome segregation and abnormal tubulin polymerization. Post-translational modifications (PTMs) play a crucial role in the functional diversity of the …

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Design and Screening of the Peptide SAMP-12aa Derived from LL-37, Which Exhibits Anti-H. Pylori Activity and Immunomodulatory Effects

Jiangbo Lu, Qi Wang, Meisong Qin, Jinfeng Dou et autres

The appearance of antibiotic-resistant strains of Helicobacter pylori (H. pylori) is leading to a decreased eradication rate of H. pylori infection. There is an urgent need to find new agents with antimicrobial mechanisms different from those of antibiotics, with therapeutic potential to …

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Novel Clinical Predictive Model for Stent Dysfunction after TIPS in Patients with Cirrhosis-Related Portal Hypertension

Lei Qin, Qing-Ao Xiao, Jing Yu, W. H. Li et autres

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Microwave-Induced Dense Crystal–Amorphous FexNiyOOH Nanosheets as Stable Electrocatalysts for Oxygen Evolution

Xiaolin Zhang, Danfeng He, Bingdong Yan, Wei Sun et autres

Interfacial engineering between crystallin and amorphous phases plays a significant role in the development of highly efficient and stable electrocatalysts. Conventional heterostructures synthesized via asynchronous methods often suffer from limited interfacial density, which compromises their durability. Here, we present densely integrated crystalline–amorphous …

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The association between per-fluoroalkyl and poly-fluoroalkyl substances exposure and thyroid cancer: a meta-analysis

Ruyu Wang, Mengze Lv, Siqi Chen, Zuoling Fu et autres

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HBV reactivation and its management in HBV-related HCC patients undergoing HAIC-TKI-ICI therapy: A multicenter study

Jiayun Liu, Bo Sun, Jiahua Zou, Xiaolin Zhang et autres

< 0.001). The additional treatment with tenofovir alafenamide fumarate can effectively manage the HBV reactivation and improve the survival of these HBV reactivated HCC patients.

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Lithium isotope fractionation in Weinan loess and implications for pedogenic processes and groundwater impact

Maoyong He, Jibao Dong, Xingxing Liu, Shugang Kang et autres

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Sodium butyrate attenuates oxidative stress, apoptosis, and excessive mitophagy in sodium fluoride-induced hepatotoxicity in rats

Jing Xia, Xiaolin Zhang, Ling Xu, Nan Yan et autres

Long-term exposure to excess sodium fluoride (NaF) can cause chronic fluorosis. Liver, the most important detoxification organ, is the most vulnerable to the effects of fluoride. Sodium butyrate (NaB), a short-chain fatty acid produced in the intestinal tract, maintains normal mitochondrial function …

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Influence of laser energy on weld quality during blue laser spot-welding of electrical steel laminations

Xiaolin Zhang, Zijue Tang, Yakai Xiao, Chang Liu et autres

Blue laser spot welding electrical steel can improve material absorption, stabilise the molten pool and reduce heat input. The influence of process parameters on the welding quality of blue laser spot welding electrical steel is investigated. With the increase of laser power, …

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PTPN11 is a potential biomarker for type 2 diabetes mellitus complicated with colorectal cancer

Sun Meiling, Zhe Han, Zhimin Luo, Lijuan Ge et autres

Epidemiological surveys have shown that the incidence of type 2 diabetes mellitus (T2DM) and malignancies is rapidly increasing worldwide and has become a major disease that threatens human life. In this study, we quantitatively analyzed the proteome of tumor tissues and adjacent …

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Blue Laser Conduction Spot Welding of Pure Copper Hairpins

Zijue Tang, Le Wan, Xiaolin Zhang, CHANG-LONG ZHU et autres

Joining rectangular copper hairpins significantly improves the performance of hairpin motors. Copper welding poses a significant challenge due to its low laser absorptivity when using conventional infrared lasers. Although employing keyhole welding with a high-power and small-spot infrared laser can increase the …

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Blue Laser Conduction Welding of Dissimilar Cu and Al Sheets

Zijue Tang, Huihui Yang, Le Wan, PENGYUAN REN et autres

Joining Cu-Al with 0.6 mm is important for the high-power density battery in the new energy field. Low laser absorptivity is a challenge in Cu-Al welding with conventional infrared laser at around 1000 nm wavelength, where keyhole welding is necessary. It is …

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