Yonggang Liu

Aqueous-Phase Polyelectrolyte Behavior of Hydroxypropyl Chitosan

Julia B. Chatterjee, Emily Krucker-Velasquez, Hiroaki Sai, Kyle J. Gray et autres

Abstract Hydroxypropyl chitosan (HPCS) is a water-soluble, cationic derivative of chitosan whose combination of hydrophilic substituents and residual charged and hydrophobic groups creates a unique landscape of interactions in aqueous media. Despite growing interest in chitosan-based materials, the fundamental solution behavior of …

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Analysis of the TGA gene family and the role of SlTGA03 in tomato resistance to Meloidogyne enterolobii

Junhong Chen, Cailan Wang, Mingming Shi, Huixia Li et autres

BACKGROUND: Tomato (Solanum lycopersicum) is an economically significant crop that faces numerous biotic stresses, particularly from Meloidogyne enterolobii. RESULTS: In this study, we investigated the role of the TGA transcription factor (TF) family in tomato resistance to M. enterolobii. A total of …

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Presymbiotic activation of karrikin signaling creates a permissive state for arbuscular mycorrhizal symbiosis by derepressing the NSP1–NSP2–SLR1 transcriptional complex in rice

Kai Hong, Xueying Yang, Yiqing Tan, Yonggang Liu et autres

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Development and validation of a predictive model for oral mucosal pressure injury risk in ICU patients with endotracheal intubation

Limei Cai, Yijing Li, Meng Zheng, Yonggang Liu et autres

Objective To identify risk factors for oral mucosal pressure injury (OMPI) in intensive care unit (ICU) patients undergoing orotracheal intubation and to develop and validate a risk prediction nomogram based on logistic regression analysis. Methods Relevant risk factors for OMPI were identified …

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Clinical characteristics of colorectal polyps in patients with non-alcoholic fatty liver disease in high altitude areas

Chunyan Wang, Lin Ma, Ying Zhao, Xiaojiang Zhang et autres

BACKGROUND Colorectal cancer has high global incidence and mortality rates. Colorectal polyps are relatively common, with adenomatous polyps having a higher risk of malignant transformation. Non-alcoholic fatty liver disease (NAFLD) has been identified as a risk factor for the development of colorectal …

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Endotracheal intubation-related oral mucosal membrane pressure injuries: a narrative review of biomechanical insights, biomaterial optimization, and intelligent monitoring

Limei Cai, Yijing Li, Yonggang Liu, Ma Guo et autres

Objectives: This article is a narrative review that synthesizes current evidence on orotracheal intubation-related oral mucosal membrane pressure injuries in intensive care unit (ICU) patients, focusing on mechanisms, risk factors, and prevention strategies. The review is intended to inform clinicians and researchers …

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Multi-target synergistic anti-aging: QG extends Caenorhabditis elegans lifespan through DAF-16/FOXO pathways, mitochondrial homeostasis and metabolic reprogramming

Jiahui Wang, Shuqi Li, Yantao Xing, Jingao Li et autres

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Ellagic acid mitigates deoxyaconitine-induced neurotoxicity by improving mitochondrial function

Wenqi Wang, Jie Qiang Guo, Danyang Ye, Rui-Guang Wu et autres

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Living/controlled supramolecular protein polymerization

Hao Ren, Qianhui Zhang, Kai Wang, Siqi Xu et autres

With the learning from living protein polymerization in nature, achieving living/controlled supramolecular assembly of biopolymers such as proteins in vitro is a longstanding challenge for material design. Herein, we provide a thiol-regulated interfacial protein aggregation (TRIPA) for unfolded protein systems with typical …

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Lactate Activates the HCAR1/β‐Arrestin2/PP2A Signaling Axis to Mediate STAT1/2 Dephosphorylation and Drive Osteosarcoma Progression

Zhitao Han, Qi Jia, Guangjian Bai, Li Zhao et autres

The "Warburg effect", a hallmark of Osteosarcoma(OS), results in lactate accumulation due to aerobic glycolysis. The role and underlying mechanisms of lactate in OS are not well understood. Herein, the lactate-activated hydroxycarboxylate receptor 1(HCAR1) is found to promote OS progression via inhibiting …

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Design of out-of-plane scanning linearization drive for waveguide beam scanner based on dual-frequency liquid crystal

Yuqing Wang, Zhihui Diao, Zekun Bi, Ao Chen et autres

Liquid crystal (LC) cladding waveguides, when used as a platform for non-mechanical beam scanning, show great potential for applications in LiDAR and free-space optical communications. Elastic recovery of the LC director deflection after voltage removal in most nematic LCs is slow and …

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Unveiling the anti-aging activities and mechanism of melibiose: insights from metabolomics and RT-qPCR analyses

Xuxu Chen, Tianyu Zheng, Zhijun Su, Shaojun Yu et autres

In this study, the anti-aging potential of melibiose was examined, and its molecular mechanism was elucidated using Caenorhabditis elegans as a model organism. The findings demonstrated that melibiose at concentrations of 100 μM, 150 μM, and 200 μM significantly increased nematode lifespan …

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