Xiaohui Li

Magnetic Resonance-Based Hemodynamic Model in Symptomatic Intracranial Atherosclerotic Disease

Lin Zhu, Zhenzhen Li, Xiaohui Li, Meng Wang et autres

BACKGROUND: Patients diagnosed with symptomatic intracranial atherosclerotic stenosis (sICAS) face an elevated likelihood of experiencing recurrent ischemic cerebrovascular events. The aim of this research was to create simplified computational fluid dynamics (CFD) models using magnetic resonance imaging (MRI) in order to explore …

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MT-DENet: Prediction of post-therapy OCT images in diabetic macular edema by multi-temporal disease evolution network

Xiaohui Li, Kun Huang, Yuhan Zhang, Songtao Yuan et autres

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Comparative Pharmacokinetics and Bioequivalence of Two Sodium Valproate Tablets in Healthy Chinese Subjects Under Fasting and Fed Conditions

Yuan Liu, Peng Hui Xu, Mengfei Zhao, Fengzhi Liu et autres

Sodium valproate, a broad-spectrum antiseizure medication of the fatty acid derivative class, was investigated in this study. The trial was designed as a single-center, open-label, randomized, 2-treatment, 4-period, 2-sequence crossover study conducted among healthy Chinese subjects. The objective was to evaluate the …

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Nitrogen-phosphorus stoichiometry and Cladophora growth affected by grass-sourced dissolved organic matter in the littoral zone of the Qinghai Lake, China

Xiaohui Li, Hongyi Ao, Kelong Chen, Chenxi Wu

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[Study on the promotion of podocyte pyroptosis by high glucose-stimulated GMC-derived exosomes and the intervention effects of Tongluo Yishen Formula].

Yan Wen, Lin Li, Liming Chen, Jie Qu et autres

Objective To investigate the effects of exosomes (Exo) derived from high glucose-stimulated glomerular mesangial cells (GMC) on the kidneys of C57BL/6 mice and the intervention mechanism of Tongluo Yishen Formula (TLYSF). Methods The rat GMC were divided into a normal glucose group …

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Clinical Guidelines for the Use of Platelet-Rich Plasma (PRP) for Osteoarthritis

Ying Zhang, Feng Shuang, Dongfa Liao, Xiaohui Li

This document specifies the requirements for institutions and personnel involved in the treatment of osteoarthritis with platelet-rich plasma (PRP), including the acquisition of PRP, the process of local injection therapy, and post-treatment patient examination and follow-up. This document is applicable to the …

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Clinical Guidelines for the Use of Platelet-Rich Plasma (PRP) for Osteoarthritis

Ying Zhang, Feng Shuang, Dongfa Liao, Xiaohui Li

This document specifies the requirements for institutions and personnel involved in the treatment of osteoarthritis with platelet-rich plasma (PRP), including the acquisition of PRP, the process of local injection therapy, and post-treatment patient examination and follow-up. This document is applicable to the …

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A Randomized, Open‐Label, Two‐Sequence, Crossover Trial Evaluating the Bioequivalence, and Pharmacokinetics of Two Sulfamethoxazole/Trimethoprim Tablet Formulations in Healthy Chinese Volunteers Under Fasting Conditions

Peng Hui Xu, Yuan Liu, Hongcheng Li, Yuyan Lei et autres

Abstract The compound sulfamethoxazole (SMZ)/trimethoprim (TMP), a dual‐agent formulation comprising SMZ and TMP, exhibits synergistic bacteriostatic and bactericidal activity by disrupting folate metabolism pathways. This study assessed the bioequivalence (BE) of a generic compound SMZ/TMP tablet versus its innovator counterpart under fasting …

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Bioequivalence Study of Two Empagliflozin Tablets in Healthy Chinese Subjects Under Fasting and Fed Conditions

Yuyan Lei, Yuan Liu, Lichen Gao, Peng Hui Xu et autres

Empagliflozin is a highly selective sodium-glucose cotransporter 2 inhibitor and an effective medication for treating diabetes. This study aimed to assess the pharmacokinetics and bioequivalence of two 10-mg empagliflozin tablets in healthy Chinese subjects and examine food's effect on absorption. The research …

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Bioactive homoisoflavonoids from the fibrous roots of Ophiopogon japonicus

Liping Feng, Zhanguo Li, Qian Ding, Chun Luo et autres

Phytochemical exploration of the fibrous roots of Ophiopogon japonicus culminated in the identification of two novel homoisoflavonoids , designated as 5- O -methylophiopogonone C ( 1 ) and (3 S )-7,2’-dihydroxy - 3’,4’-methylenedioxyhomoisoflavan ( 2 ). Leveraging an array of advanced spectroscopic …

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[Effect of Chaihu Jia Longgu Muli Decoction on apoptosis in rats with heart failure after myocardial infarction through IκBα/NF-κB pathway].

Yizhuo Li, Xingyuan Li, Gang Liu, Xiaohui Li et autres

This study aims to explore the protective effect of Chaihu Jia Longgu Muli Decoction on rats with heart failure after myocardial infarction, and to clarify its possible mechanisms, providing a new basis for basic research on the mechanism of classic Chinese medicinal …

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Corrigendum to “Plasma reference interval of Trimethylamine-N-oxide in healthy adults: A multicenter study using Trimethylamine-N-oxide assay kit for analysis and validation” [Clin. Chim. Acta. 571 (2025) 120223]

Qing Fang, Yuyan Lei, Hao Wu, Chao Li et autres

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