Xueqin Wang

Lipid–metabolic risk stratification for carotid plaque in adults under 50 years undergoing health examinations: cross-sectional modeling and same-center longitudinal validation

Hailong QI, Xiaoyu Zhang, Kaixuan ZHENG, Xueqin Wang et autres

Carotid plaque is an imaging marker of early subclinical atherosclerosis. Adults under 50 years of age undergoing health examinations often have low short-term absolute cardiovascular risk, yet adverse lipid–metabolic profiles may already be associated with early plaque formation. This study aimed to …

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TSG-6 protects orbital fibroblasts via anti-inflammation and anti-fibrosis effects in thyroid eye disease

Siya Chen, X He, J M Chen, Xueqin Wang et autres

Tumor necrosis factor-α-stimulated gene-6(TSG-6), a secreted protein with anti-inflammatory and tissue-protective properties, mediates a cascade of proinflammatory cytokines and ameliorates tissue fibrosis. Previous studies have found that TSG-6 can attenuate the degree of fibrosis, inhibit the inflammatory response, and reduce adipogenesis in …

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Regulating Anderson Localization in Flexible Order‐in‐Disorder Metasurfaces for Robust SERS

Xueqin Wang, Fajun Li, Jiaqing Shen, S M Yang et autres

ABSTRACT Surface‐enhanced Raman spectroscopy (SERS) has achieved extensive applications through carefully engineered plasmonic metasurfaces. Disordered plasmonic metasurfaces are widely used for SERS applications due to their simple fabrication and low cost. However, their poor spatial uniformity usually causes severe signal fluctuations, degrading …

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Dynamic Non-HDL-C Exposure and Carotid Plaque Development in a Longitudinal Health-Check Cohort: a Retrospective Cohort Study

Hailong QI, Xiaoyu ZHANG, Kaixuan ZHENG, Xueqin Wang et autres

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Morus alba L. (Sangzhi) alkaloids reduce polycystic ovary syndrome by improving hypothalamic-pituitary-ovarian axis function

Yuanyuan Liu, 吴若妍, Huijuan Li, Danfeng Pu et autres

BACKGROUND: Polycystic ovary syndrome (PCOS) is a neuroendocrine-metabolic disorder with no approved drugs. Hypothalamic-pituitary-ovarian (HPO) axis dysfunction is core pathogenesis, and metabolic heterogeneity complicates treatment. Existing medications rarely ameliorate PCOS comprehensively. Sangzhi alkaloids (SZ-A), an extract from Morus alba L. twigs approved …

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Study protocol of a multicenter, randomized, non-inferiority, open-label study investigating the efficacy of a fixed-dose combination regimen of dapagliflozin/metformin versus co-administered dual therapy based on glycemic control, satisfaction and adherence in patients with newly diagnosed type 2 diabetes mellitus

Jiaxuan Wang, Ying Wei, Ping Shi, Chen Ji et autres

Introduction: The combination of dapagliflozin and metformin is commonly used as an initial therapy for patients with type 2 diabetes mellitus (T2DM) with high glycated hemoglobin (HbA1c) levels. Although bioequivalence has been established for the fixed-dose combination (FDC) of dapagliflozin/metformin extended-release (XR) …

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Perillaldehyde Attenuates Insulin Resistance and High Glucose-Induced Ferroptosis in Trophoblast Cells via Regulation of PTPN1/Akt/Foxo1 Signaling Pathway

Xing Wang, Yujie Lu, Suyu Wang, Xueqin Wang et autres

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[Retracted] Sevoflurane attenuates brain damage through inhibiting autophagy and apoptosis in cerebral ischemia‑reperfusion rats

Cunxian Shi, Jin Jin, Xueqin Wang, Teng Song et autres

Following the publication of this paper, it was drawn to the Editor’s attention by a concerned reader that, regarding the immunohistochemistry experiments shown in Fig. 4A, the ‘Tak‑242’ and the ‘Se+Tak‑242’ panels appeared to show an overlapping section of data, and for …

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AFF4 promotes tumor progression and cisplatin resistance by modulating the PTEN/PI3K/AKT/mTOR axis to accelerate glycolysis in lung adenocarcinoma

Xufeng Yao, Qian Chai, Yuhao Ma, Guomeng Li et autres

BACKGROUND: Although aerobic glycolysis contributes to malignancy and drug resistance in human cancers, the vital regulators of glycolysis in lung adenocarcinoma (LUAD) remain largely unknown. Transcription factor AF4/FMR2 family member 4 (AFF4) is the scaffolding protein of the super elongation complex (SEC) …

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Intelligent non-destructive biosensing of fresh tea leaves by portable spectroscopy and enhanced transformer

Kaibin Chen, Yuan Z. Gao, Zhipeng Zhang, Yueyue Zhu et autres

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Dynamic characterization of tool-chip contact area and chip form

Hao Xu, Zhaocheng Wei, Xiuru Li, Xueqin Wang et autres

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Fabrication, characterization, stability and re-dispersity of H-aggregates fucoxanthin/whey protein/chitosan nanoparticles

Yingyuan Zhao, Yuting Sun, Yuqing Chen, Wen-Hui Qu et autres

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