Sandip D. Kamath

Unique Sensitization Patterns to Allergen Components in a Crustacean‐Allergic Australian Cohort

Elecia B. Johnston, Sahel Heidari, Shaymaviswanathan Karnaneedi, Diamond Hira et autres

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(005) Young Ehlers-Danlos Syndrome Mice Have Increased Penile and Vaginal Adrenergic Contraction

Sandip D. Kamath, Andrew T Readyoff, Norman B. Williamson, Everett C. Minchew et autres

Abstract Introduction Ehlers-Danlos syndrome (EDS) is an inherited connective tissue disorder characterized by collagen abnormalities, leading to tissue fragility. Individuals with EDS often experience urinary incontinence, pelvic pain, and sexual dysfunction, with a higher prevalence in female (73–89%). Classic EDS (type 1) …

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Advanced Simulation-Based Design Exploration and Optimization for Challenging Flexible Flowline Loading Impacts on Various Subsea Connection Systems

Catarina Noronha, Sandip D. Kamath, Jennifer J. Roberts, Mark Andrew Lee et autres

Abstract Vertical connection systems are widely used in offshore production for the oil and gas industry, where the loadings from the connected flowline have a significant influence on the tie-in connection, host structure design, and foundation capacities. The objective is to explore …

Dissecting the Sensitization Profiles in Parvalbumins From 12 Freshwater Fish Species to Improve Diagnosis of Fish Allergy

Sandip D. Kamath, Nina Lengger, S Ottersbach, K Uranowska-Kostrubala et autres

BACKGROUND AND OBJECTIVES: Background: Many fish-allergic patients only react to certain fish species and may tolerate others, mostly because of IgE-mediated recognition of specific epitopes on the major allergen parvalbumin. However, the considerable number of fish species consumed makes it challenging to …

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361P Development of a next-generation multiplex ddPCR assay for measurement of in-frame dystrophin mRNA in people with DMD treated with BMN 351

S. TAMURA, Ikjot Sidhu, Jose Ilagan, Aibing Yu et autres

Schistosoma excretory/secretory products: an untapped library of tolerogenic immunotherapeutics against food allergy

Madeleine J. Rogers, Sandip D. Kamath, Donald Peter McManus, Malcolm K. Jones et autres

Abstract Food allergy (FA) is considered the ‘second wave’ of the allergy epidemic in developed countries after asthma and allergic rhinitis with a steadily growing burden of 40%. The absence of early childhood pathogen stimulation embodied by the hygiene hypothesis is one …

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The Allergen Profile of Two Edible Insect Species— Acheta domesticus and Hermetia illucens

Shaymaviswanathan Karnaneedi, Elecia B. Johnston, Utpal Bose, Angéla Juhász et autres

SCOPE: Edible insect proteins are increasingly introduced as an alternative sustainable food source to address the world's need to feed the growing population. Tropomyosin is the main insect allergen; however, additional potential allergens are not well characterized and the impact of extraction …

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Variation in Shrimp Allergens: Place of Origin Effects on Food Safety Assessment

Ryley Dorney, Elecia B. Johnston, Shaymaviswanathan Karnaneedi, Thimo Ruethers et autres

Due to the widespread use of shellfish ingredients in food products, accurate food labelling is urgently needed for consumers with shellfish allergies. Most crustacean allergen detection systems target the immunorecognition of the allergenic protein tropomyosin. However, this mode of detection may be …

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Multinational study of allergic sensitization to ten fish species indicates patient-dependent tolerance of specific fish

Tanja Kalic, Annette Kuehn, Martina Aumayr, Joan Bartra et autres

Background: Recent studies indicated that fish-allergic patients may safely consume certain fish species. Multiplex IgE testing facilitates the identification of species tolerated by individual patients. Methods: Sera were collected from 263 fish-allergic patients from Austria, China, Denmark, Luxembourg, Norway and Spain. Specific …

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Tropomyosin: A cross-reactive invertebrate allergen

Sandip D. Kamath

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Hypoallergenic chimeric virus‐like particles for the development of shrimp tropomyosin allergen Pen m 1‐specific blocking antibodies

Supapich Chanasit, Elecia B. Johnston, Chanatip Thanasarnthungcharoen, Sandip D. Kamath et autres

The data that support the findings of this study are available from the corresponding author upon reasonable request. Data S1. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries …

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Commercial shellfish skin prick test extracts show critical variability in allergen repertoire

Thimo Ruethers, Elecia B. Johnston, Shaymaviswanathan Karnaneedi, Shuai Nie et autres

[Extract] Crustacean and mollusc (shellfish) allergy affects up to 3% of the general population, is usually lifelong and commonly triggers anaphylaxis.1 Allergen repertoire diversity among hundreds of edible shellfish species worldwide is poorly reflected in available in vivo and in vitro diagnostic …

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