Accès ouvert
2026
article
OpenAlex
Siyi Rao, Mengjie Weng, Yongjie Zhuo, Jiaqun Lin et autres
The role of gluconeogenesis in kidney disease has increasingly drawn attention. Fructose-1,6-bisphosphatase 1 (FBP1) is a key rate-limiting enzyme in gluconeogenesis that suppresses glycolysis and reduces lactate production. In this study, we first analyzed public transcriptomic datasets of diabetic kidney disease (DKD) …
cn
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Accès ouvert
2025
article
OpenAlex
Zhenzhou Li, Liyan Yang, Mengjie Weng, Jiaqun Lin et autres
Objective This study aimed to delineate the risk factors affecting renal outcomes in autoimmune membranous nephropathy (aMN) with or without acute kidney injury (AKI) and develop a predictive model. Methods This retrospective cohort study included 441 patients with biopsy-confirmed aMN from the …
cn
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Accès ouvert
2024
article
OpenAlex
Jing Zhang, Siyu Chen, Haiying Zheng, Siyi Rao et autres
Background In recent years, ectopic lymphoid tissue (ELT) has been increasingly confirmed as a new biomarker for kidney injury or inflammation. However, there is insufficient research on the relationship between ELT grading and the progression of idiopathic membranous nephropathy (IMN). Methods A …
cn
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Accès ouvert
2024
article
OpenAlex
Siyi Rao, Mengjie Weng, Ruoshan Lian, Yongjie Zhuo et autres
AIMS: We aim to explore the correlation between coronary artery calcification (CAC) score (CACS) and cardiac structure and function in chronic kidney disease (CKD) patients, create a clinical prediction model for severe CAC associated with cardiac ultrasound indexes. METHODS AND RESULTS: The …
cn
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Accès ouvert
2024
article
OpenAlex
Jing Zhang, Ruoshan Lian, Yi Chen, Jianxin Wan
Objective To investigate the correlations between serum antineutrophil cytoplasmic antibody (ANCA) and clinicopathological features, induction treatment response, and prognosis of lupus nephritis (LN) patients.Methods In this retrospective study, biopsy-proven LN patients from October 2010 to September 2020 were tested for serum ANCA …
cn
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Accès ouvert
2022
article
OpenAlex
Siyi Rao, Jing Zhang, Jiaqun Lin, Jianxin Wan et autres
Introduction: With the invention and improvement of the carbon monoxide (CO) breath test, the role of shortened red blood cell life span (RBCLS) in renal anemia, an independent risk factor for cardiovascular events in patients with chronic kidney disease (CKD), is gradually …
cn
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Accès ouvert
2022
article
OpenAlex
Mengjie Weng, Jiaqun Lin, Yumei Chen, Xiaohong Zhang et autres
We aim to investigate the association of time-averaged hematuria (TA-hematuria) with the progression of IgA nephropathy (IgAN). Based on TA-hematuria during follow-up, 152 patients with IgAN were divided into a hematuria remission group (≤28 red blood cells [RBCs]/μL) and a persistent hematuria …
cn
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