Gert Baumann

New Approach To Heart Rate Variability Analysis Based On Cardiophysiological Biomarkers

Ludmila Sidorenko, Ivan Diaz-Ramirez, Victor Vovc, Gert Baumann

Background: The heart rate variability (HRV) analysis is a well-known method demonstrating its value over the years in different medical fields. However, it still has its known limitations. Material and methods: The new approach to HRV analysis is based on a complementary …

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P1488Treatment of severe tricuspid regurgitation in patients with advanced heart failure with caval vein implantation of the edwards sapien XT valve (TRICAVAL): a controlled prospective randomized trial

Michael Laule, Isabel Mattig, Bernd Hewing, Christoph Schoebel et autres

Purpose: Tricuspid regurgitation (TR) is a frequent comorbidity in patients with advanced heart failure and associated with high morbidity and mortality. As surgical repair carries a high risk for postoperative complications in these patients, innovative interventional therapies of TR are an unmet …

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Immunoproteasome subunit ß5i/LMP7-deficiency in atherosclerosis

Bernd Hewing, Antje Ludwig, Cristian Dan, Max Pötzsch et autres

Abstract Management of protein homeostasis by the ubiquitin-proteasome system is critical for atherosclerosis development. Recent studies showed controversial results on the role of immunoproteasome (IP) subunit β5i/LMP7 in maintenance of protein homeostasis under cytokine induced oxidative stress. The present study aimed to …

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Additional Heart Sound in Aortic Aneurysm Caused by Prolapse of the Dissection Flap into the Left Ventricle

Silvana Müller, Thomas Bartel, Karl Stangl, J. Böhm et autres

An uncommon middiastolic click was heard in 2 cases of dissecting aortic aneurysm. Transesophageal echocardiography revealed prolapse of the intima flap into the left ventricle. The rare but specific auscultatory finding of an additional heart sound may prevent wrong treatment by thrombolysis …

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Tea-induced improvement of endothelial function in humans: No role for epigallocatechin gallate (EGCG)

Mario Lorenz, Franziska Rauhut, Christine Höfer, Stefanie Gwosc et autres

Consumption of tea is inversely associated with cardiovascular diseases. However, the active compound(s) responsible for the protective effects of tea are unknown. Although many favorable cardiovascular effects in vitro are mediated by epigallocatechin gallate (EGCG), its contribution to the beneficial effects of …

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Long-Term Effect of Endothelin Receptor Antagonism With Bosentan on the Morbidity and Mortality of Patients With Severe Chronic Heart Failure

John J.V. McMurray, Henry Krum, Barry M. Massie, Avi Caspi et autres

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Severe Aortic Valve Stenosis in Adults is Associated with Increased Levels of Circulating Intermediate Monocytes

Bernd Hewing, Sebastian Chi-Diep Au, Antje Ludwig, Rena Ellerbroek et autres

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Levels of Circulating Intermediate Monocytes Decrease after Aortic Valve Replacement in Patients with Severe Aortic Stenosis

Bernd Hewing, Rena Ellerbroek, Sebastian Chi-Diep Au, Verena Stangl et autres

Aortic valve stenosis (AS) is a chronic inflammatory disease. We have previously shown that severe AS is associated with increased levels of circulating intermediate monocytes. Haemodynamics are considered to influence levels of circulating monocyte subsets; we therefore hypothesized that aortic valve replacement …

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Erratum to: Uptake of citrate-coated iron oxide nanoparticles into atherosclerotic lesions in mice occurs via accelerated transcytosis through plaque endothelial cells

Wolfram C. Poller, Evelyn Ramberger, Philipp Boehm‐Sturm, Susanne Mueller et autres

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Uptake of citrate-coated iron oxide nanoparticles into atherosclerotic lesions in mice occurs via accelerated transcytosis through plaque endothelial cells

Wolfram C. Poller, Evelyn Ramberger, Philipp Boehm‐Sturm, Susanne Mueller et autres

Abstract Very small superparamagnetic iron oxide nanoparticles (VSOPs) rapidly accumulate in atherosclerotic lesions, thereby enabling plaque visualization by magnetic resonance imaging (MRI). This study was performed to identify the uptake mechanisms of VSOPs into atherosclerotic plaques. Low-density lipoprotein receptor-deficient (LDLR−/−) mice with …

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Mid-regional pro-adrenomedullin (MR-proADM) and mid-regional pro-atrial natriuretic peptide (MR-proANP) in severe aortic valve stenosis: association with outcome after transcatheter aortic valve implantation (TAVI)

Gerd Baldenhofer, Michael Laule, Martin Möckel, Wasiem Sanad et autres

BACKGROUND: This study aimed to assess the association of mid-regional (MR) pro-adrenomedullin (MR-proADM) and MR-pro-A-type natriuretic peptide (MR-proANP) in comparison to N-terminal pro-natriuretic peptide (NT-proBNP) with outcome in patients with aortic stenosis (AS) treated with transcatheter aortic valve implantation (TAVI). METHODS: One …

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Assessing cardiac autonomic function via heart rate variability analysis requires monitoring respiration

Niels Wessel, Л. П. Сидоренко, Jan F. Kraemer, Christoph Schoebel et autres

With great interest we have read the joint position statement about advances in heart rate variability (HRV) signal analysis presented by Dr Sassi et al.1 They present a critical review of newly developed HRV methodologies developed after publication of the initial Task …

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