Yi Sun

WTAP-mediated m6A modification of UBE2K drives the malignant progression of gastric cancer

Junwei Guo, Zhe Zhang, Yi Sun, Zhiwei Yu et autres

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Letter Regarding: Barriers and Facilitators to Enhanced Recovery Protocol Implementation for Neonatal Intestinal Surgery

Yi Sun

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Post-Pancreatectomy Diabetes: Is it Steatosis or the Standard Adjuvant Therapy?

Yi Sun

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Ubiquitin-specific peptidase 40 promotes cellular proliferation and inhibits apoptosis through deubiquitination-mediated stabilization of c-MYC in acute myeloid leukemia

Wenbin Fu, Qiaoliang Wu, Yanru Yao, Yi Sun et autres

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Protocol to isolate broadly neutralizing monoclonal antibodies against SARS-CoV-2 from human B cells

Xueyan Huang, Maosheng Lu, Ling Li, Zuowei Wang et autres

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Palladium-Catalyzed Late-Stage Maleimidation of Phenylalanine-Containing Peptides

Yi Sun, Qi Lu, Fengjie Lu, Shina Yan

The incorporation of bioactive fragments or non-natural covalent linkages has shown to significantly improve the chemical stability and biological activity of peptides. In this study, we have developed a novel methodology for site-selective Pd-catalyzed maleimidation of phenylalanine-containing peptides. This synthetic strategy offers …

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The Spatiotemporal Evolution and Multi-Scenario Simulation of Carbon Storage in the Middle Reaches of the Yangtze River Based on the InVEST-PLUS Model

Long‐Qing Chen, Yi Sun, Diwei Tang, Jian Song et autres

The middle reaches of the Yangtze River are important bases for high-tech, advanced manufacturing, and modern service industries in China, as well as a demonstration area for the coordination of economic and ecological construction, which plays an important role in the ecosystem …

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A rare B cell clonotype imprinted by ancestral SARS-CoV-2 develops cross-sarbecovirus neutralization in immune recalls

Xixian Chen, Ling Li, Ruiping Du, Zuowei Wang et autres

The ultimate potential of B cells imprinted by ancestral SARS-CoV-2 in developing neutralizing breadth and potency remains to be explored. Here, we longitudinally tracked B cells that recognize the wild-type spike in two individuals who were repeatedly infected by Omicron variants after …

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Discovery of Synergistic Broadly Neutralizing Antibodies Targeting Non-Dominant Epitopes on SARS-CoV-2 RBD and NTD

Hualong Feng, Zuowei Wang, Ling Li, Yunjian Li et autres

Background/Objectives: Identification and characterization of broadly neutralizing monoclonal antibodies from individuals exposed to SARS-CoV-2, either by infection or vaccination, can inform the development of next-generation vaccines and antibody therapeutics with pan-SARS-CoV-2 protection. Methods: Through single B cell sorting and RT-PCR, monoclonal antibodies …

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The Association Between Ambient Fine Particulate Matter and Spontaneous Preterm Birth: Evidence From a Large Pregnancy Cohort in Southern California [ID 1244]

Alexa N. Reilly, Anqi Jiao, Tarik Benmarhnia, Yi Sun et autres

INTRODUCTION: Although studies have found positive associations between exposure to PM2.5 and preterm birth, distinguishing between spontaneous preterm birth (sPTB) and iatrogenic preterm birth (iPTB) was a challenge in previous research. This study examined associations between total PM2.5 and PM2.5 constituent exposure …

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Fine Particulate Matter, Its Constituents, and Spontaneous Preterm Birth

Anqi Jiao, Alexa N. Reilly, Tarik Benmarhnia, Yi Sun et autres

(Abstracted from JAMA Network Open 2024;7(11):e2444593) Spontaneous preterm birth (sPTB) occurs following spontaneous labor or preterm premature rupture of membranes. It accounts for up to 70% of all preterm births (PTBs) and can result from infection or inflammation, decidual hemorrhage, uterine over …

Breakthrough infection elicits synergistic broadly neutralizing antibodies targeting non-dominant epitopes on RBD and NTD in an individual of inactivated SARS-CoV-2 vaccine

Zuowei Wang, Hualong Feng, Ling Li, Yunjian Li et autres

Abstract Background/Objectives Identification and characterization of broadly neutralizing monoclonal antibodies from individuals exposed to SARS-CoV-2, either by infection or vaccination, can inform the development of next-generation vaccines and antibody therapeutics with pan-SARS-CoV-2 protection. Methods Through single B cell sorting and RT-PCR, monoclonal …

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