James Olcese

Melatonin receptors in GtoPdb v.2025.3

Daniel P. Cardinali, Gianluca Tosini, David Sugden, Nicolas Renault et autres

Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [40]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.

ar, us, gb, fr, es, Égypte (code pays fourni par la source)

Melatonin receptors in GtoPdb v.2023.1

Daniel P. Cardinali, Philippe Delagrange, Margarita L. Dubocovich, Ralf Jockers et autres

Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [40]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.

ar, fr, us, es, gb, Égypte (code pays fourni par la source)

Melatonin receptors in GtoPdb v.2021.3

Daniel P. Cardinali, Philippe Delagrange, Margarita L. Dubocovich, Ralf Jockers et autres

Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [40]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.

ar, fr, us, es, gb, Égypte (code pays fourni par la source)

Myths and Evidence Regarding Melatonin Supplementation for Occasional Sleeplessness in the Pediatric Population

Ran D. Goldman, Peter B. Bongiorno, James Olcese, Paula A. Witt‐Enderby et autres

Occasional sleeplessness in children is common, with as many as 25% of all healthy children experiencing a problem sleeping at some point over the course of their childhood. Occasional sleeplessness is poorly understood, has a significant impact on quality of life in …

Mesenchymal stem cell-derived extracellular vesicles ameliorate Alzheimer's disease-like phenotypes in a preclinical mouse model

Allaura S. Cone, Xuegang Yuan, Li Sun, Leanne C. Duke et autres

Alzheimer's disease (AD) is an irreversible neurodegenerative disorder that affects more than 44 million people worldwide.Despite the high disease burden, there is no effective treatment for people suffering from AD. Mesenchymal stem cells (MSCs) are multipotent stromal cells that have been widely …

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Editorial: Melatonin in Health and Disease

James Olcese, Ralf Jockers

EDITORIAL article Front. Endocrinol., 26 November 2020 | https://doi.org/10.3389/fendo.2020.613549

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The Pineal and Reproduction in Fish, Amphibians, and Reptiles

Victor de Vlaming, James Olcese

Hydroxyindole-O-methyltransferase (HIOMT) was first shown to be present in the amphibian brain by W. B. Quay. Interestingly, retinal HIOMT activity is substantially greater than pineal HIOMT activity in amphibians, when tissues are collected in the middle of the light phase during the …

Melatonin and Female Reproduction: An Expanding Universe

James Olcese

For more than a half century the hormone melatonin has been associated with vertebrate reproduction, particularly in the context of seasonal breeding. This association is due in large measure to the fact that melatonin secretion from the pineal gland into the peripheral …

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Melatonin receptors (version 2019.4) in the IUPHAR/BPS Guide to Pharmacology Database

Daniel P. Cardinali, Philippe Delagrange, Margarita L. Dubocovich, Ralf Jockers et autres

Melatonin receptors (nomenclature as agreed by the NC-IUPHAR Subcommittee on Melatonin Receptors [36]) are activated by the endogenous ligands melatonin and clinically used drugs like ramelteon, agomelatine and tasimelteon.

ar, fr, us, es, gb, Égypte (code pays fourni par la source)

Relationship between endogenous melatonin concentrations and uterine contractions in late third trimester of human pregnancy

Shadab A. Rahman, Carolina Bibbo, James Olcese, Charles A. Czeisler et autres

In humans, circulating levels of the hormone melatonin and the initiation of spontaneous labor are both higher at night than during the day. Since activation of uterine melatonin receptors can stimulate human in vitro uterine contractions and these receptors are only expressed …

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Extraction of Extracellular Vesicles from Whole Tissue

Stephanie N. Hurwitz, James Olcese, David G. Meckes

Circulating and interstitial small membrane-bound extracellular vesicles (EVs) represent promising targets for the development of novel diagnostic or prognostic biomarker assays, and likely serve as important players in the progression of a vast spectrum of diseases. Current research is focused on the …

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Extraction of Extracellular Vesicles from Whole Tissue

Stephanie N. Hurwitz, James Olcese, David G. Meckes

Circulating and interstitial small membrane-bound extracellular vesicles (EVs) represent promising targets for the development of novel diagnostic or prognostic biomarker assays, and likely serve as important players in the progression of a vast spectrum of diseases. Current research is focused on the …

us (code pays fourni par la source)