Accès ouvert
2026
preprint
OpenAlex
Madeleine H. Lackman, Christopher P. Wardell, Emilie Darrigues, Annick De Loose et autres
Abstract Linking glioblastoma (GBM) evolution to clinical progression is challenged by multiple factors, including tumor location for repeated sample collection, and short patient survival. In a single individual, we collected and analysed samples from 11 operations distributed across 31 months of multi-relapsing …
fi, us
(code pays fourni par la source)
2025
conference-abstract
OpenAlex
Orthi Shahzad, Richard Norris, Niels Weinhold, Charlotte Pawlyn et autres
Abstract Introduction: Multiple Myeloma (MM) is a heterogeneous disease making it difficult to accurately predict the disease course in individual patients. Staging systems in MM have evolved, firstly the International Staging System (ISS), then incorporation of genomic aberrations with revised-ISS. Recently, the …
gb, es, de, us
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Hayley M. Sabol, Aric Anloague, Japneet Kaur, Cecile Bustamante-Gomez et autres
BACKGROUND: Multiple myeloma (MM) is associated with a debilitating bone disease that poses significant therapeutic challenges. MM bone disease is characterized by increased bone resorption and suppression of osteoblasts, which hinders the repair of damaged bone. Sclerostin, an antagonist of Wnt signaling, …
us, dk
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Dan C. Mann, Michael Rutherford, Phillip Farmer, Joshua M. Eichhorn et autres
Skellytour provides open-source, generalizable bone segmentation and subsegmentation models for whole-body CT data that perform consistently across a range of datasets, including low-density bone.
us
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
William J. Shelton, Sara Zandpazandi, James Stephen Nix, Murat Gökden et autres
Brain tumors and genomics have a long-standing history given that glioblastoma was the first cancer studied by the cancer genome atlas. The numerous and continuous advances through the decades in sequencing technologies have aided in the advanced molecular characterization of brain tumors …
us
(code pays fourni par la source)
2024
conference-abstract
OpenAlex
Grace Guzman, Sahana Bettadapura, William Jeremy Shelton-Correa, Taylor Brooks et autres
Abstract Despite the advances in precision oncology, genomic approaches have not significantly improved outcomes for high grade gliomas (HGGs) as once was anticipated. Recurrent HGG pose even greater therapeutic challenge. The integration of functional precision medicine (FPM), in which drugs screens are …
us
(code pays fourni par la source)
2023
article
OpenAlex
Rebekah G. Langston, Heather Pinckard-Dover, Grace Guzman, Christopher P. Wardell et autres
us
(code pays fourni par la source)
Accès ouvert
2023
supplementary-materials
OpenAlex
Kevin D. Boyd, Fiona M. Ross, Laura Chiecchio, Gian Paolo Dagrada et autres
Supplementary Table 1 from Gender Disparities in the Tumor Genetics and Clinical Outcome of Multiple Myeloma
Accès ouvert
2023
other
OpenAlex
Kevin D. Boyd, Fiona M. Ross, Laura Chiecchio, Gian Paolo Dagrada et autres
Abstract Background: Several cancer types have differences in incidence and clinical outcome dependent on gender, but these are not well described in myeloma. The aim of this study was to characterize gender disparities in myeloma. Methods: We investigated the association of gender …
Accès ouvert
2023
other
OpenAlex
Kevin D. Boyd, Fiona M. Ross, Laura Chiecchio, Gian Paolo Dagrada et autres
Abstract Background: Several cancer types have differences in incidence and clinical outcome dependent on gender, but these are not well described in myeloma. The aim of this study was to characterize gender disparities in myeloma. Methods: We investigated the association of gender …
Accès ouvert
2023
supplementary-materials
OpenAlex
Kevin D. Boyd, Fiona M. Ross, Laura Chiecchio, Gian Paolo Dagrada et autres
Supplementary Methods, References, Legends for Table 1 and Figure 1 from Gender Disparities in the Tumor Genetics and Clinical Outcome of Multiple Myeloma
gb
(code pays fourni par la source)
Accès ouvert
2023
supplementary-materials
OpenAlex
Kevin D. Boyd, Fiona M. Ross, Laura Chiecchio, Gian Paolo Dagrada et autres
Supplementary Table 2 from Gender Disparities in the Tumor Genetics and Clinical Outcome of Multiple Myeloma