The dynamic exchange of subunits in Complex I is essential for its function in differentiated cells
Ilka Wittig, Paulina Castaneda Tamez, Alfredo Cabrera‐Orefice, Juliana Heidler et autres
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Ilka Wittig, Paulina Castaneda Tamez, Alfredo Cabrera‐Orefice, Juliana Heidler et autres
de, at (code pays fourni par la source)
Ilka Wittig, Juliana Heidler, Heiko Giese, Ralf Peter Brandes
de (code pays fourni par la source)
Heiko Giese, Jana Meisterknecht, Juliana Heidler, Ilka Wittig
de (code pays fourni par la source)
Karolina Szczepanowska, Katharina Senft, Juliana Heidler, Marija Herholz et autres
Regulation of the turnover of complex I (CI), the largest mitochondrial respiratory chain complex, remains enigmatic despite huge advancement in understanding its structure and the assembly. Here, we report that the NADH-oxidizing N-module of CI is turned over at a higher rate …
de, nl, us (code pays fourni par la source)
Simranjit X. Singh, Simon Lämmle, Heiko Giese, Susanne Kämmerer et autres
Abstract Heart failure is the most common cause of morbidity and hospitalization in the western civilization. Protein phosphatases play a key role in the basal cardiac contractility and in the responses to β-adrenergic stimulation with type-1 phosphatase (PP-1) being major contributor. We …
de (code pays fourni par la source)
Jennifer Hannig, Heiko Giese, Börje Schweizer, Leonie K. Amstein et autres
SUMMARY: isiKnock is a new software that automatically conducts in silico knockouts for mathematical models of signaling pathways. The software allows for the prediction of the behavior of biological systems after single or multiple knockout. The implemented algorithm applies transition invariants and …
de (code pays fourni par la source)
Jennifer Scheidel, Heiko Giese, Börje Schweizer, Leonie K. Amstein et autres
Abstract Summary isiKnock is a new software that automatically conducts in silico knockouts for mathematical models of biochemical pathways. The software allows for the prediction of the behavior of biological systems after single or multiple knockout. The implemented algorithm applies transition invariants …
de (code pays fourni par la source)
Valentina Strecker, Zibirnisa Kadeer, Juliana Heidler, Cristina‐Maria Cruciat et autres
de, us (code pays fourni par la source)
Heiko Giese, Jörg Ackermann, Ulrich Brandt, Ilka Wittig et autres
Dysfunctional protein complexes are often associated with diseases. To develop effective treatments it is essential to understand the composition, formation and functionality of protein complexes. Novel techniques like complexome profiling give an overview of possible protein-protein interactions in an entire sample. In …
de, nl (code pays fourni par la source)
Heiko Giese, Jörg Ackermann, Ulrich Brandt, Ilka Wittig et autres
Dysfunctional protein complexes are often associated with diseases. To develop effective treatments it is essential to understand the composition, formation and functionality of protein complexes. Novel techniques like complexome profiling give an overview of possible protein-protein interactions in an entire sample. In …
de, nl (code pays fourni par la source)
Heiko Giese, Jörg Ackermann, Heinrich Heide, Lea Bleier et autres
SUMMARY: We introduce nova, a software for the analysis of complexome profiling data. nova supports the investigation of the composition of complexes, cluster analysis of the experimental data, visual inspection and comparison of experiments and many other features. AVAILABILITY AND IMPLEMENTATION: nova …
de, nl (code pays fourni par la source)
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