Yoshihiro Mimaki

Agapanthussaponin A from the Underground Parts of Agapanthus africanus Induces Apoptosis and Ferroptosis in Human Small-Cell Lung Cancer Cells

Tomoki Iguchi, Tamami Shimazaki, Yoshihiro Mimaki

To explore the potential seed compounds from natural products as anticancer agents against small-cell lung cancer (SCLC), the underground parts of Agapanthus africanus, a plant commonly used for ornamental purposes, were investigated. Three spirostan-type steroidal glycosides (1–3) were isolated and identified by …

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Hesperetin Ameliorates Inhibition of Neuronal and Oligodendroglial Cell Differentiation Phenotypes Induced by Knockdown of Rab2b, an Autism Spectrum Disorder-Associated Gene Product

Yukino Kato, Remina Shirai, Katsuya Ohbuchi, Hiroaki Oizumi et autres

Autism spectrum disorder (ASD) is a central nervous system (CNS) neurodevelopmental disorder that includes autism, pervasive developmental disorder, and Asperger's syndrome. ASD is characterized by repetitive behaviors and social communication deficits. ASD is thought to be a multifactorial disorder with a range …

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Determination of oxalic acid in herbal medicines by semi-micro hydrophilic interaction liquid chromatography coupled with electrochemical detection

A. Kotani, Hisanobu Ishikawa, Takashi Shii, Minpei Kuroda et autres

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Sheep poisoning by Panicum dichotomiflorum in northeastern Brazil

Franklin Riet-Corrêa, Mitsue Haraguchi, Antônio Flávio Medeiros Dantas, Rodrigo G. Burakovas et autres

Different species of Panicum, including P. dichotomiflorum,have been reported as a cause of photosensitization in sheep, horses, cattle and goats. An outbreak of hepatogenous photosensitization occurred in 3 flocks of hair sheep in the Brazilian semiarid region. Eighty one out of 365 …

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