Estifanos Ele Yaya

Antibiotic persistence in landfill leachate and associated fluvial contamination at the Repi landfill, Ethiopia

Joan Beryl Achar, Feleke Zewge, Estifanos Ele Yaya, Bhagwan Singh Chandravanshi

The Repi landfill in Addis Ababa, Ethiopia, features Africa’s first Waste-to-Energy plant and the Fukuoka semi-aerobic method, yet persistent pharmaceutical occurrence remains a critical knowledge gap. This study provides the first evaluation of how a newly implemented single-pond mechanical surface aeration system …

Éthiopie (code pays fourni par la source)

Assessment of uptake, translocation and accumulation of three selected veterinary antibiotics by cabbage plant using HPLC-DAD and LC-MS

Serkalem Abera, Estifanos Ele Yaya, Bhagwan Singh Chandravanshi

Plants absorb, translocate and accumulate antibiotic residues or their active metabolites via their roots. The buildup of these antibiotics or their active metabolites in the plant parts, soil, surface and groundwater put the human health and the ecosystem in danger. Nevertheless, there …

Éthiopie (code pays fourni par la source)

Evaluation of 2,2-diphenyl-1-picrylhydrazyl scavenging activity and ferric reducing antioxidant power assays of six cephalosporin antibiotics

Serkalem Abera, Bhagwan Singh Chandravanshi, Estifanos Ele Yaya

Cephalosporins are the most commonly used antibiotic class, with a broad spectrum of action. However, little is known about their radical scavenging activity. Therefore, the objective of this study is to evaluate the antioxidant activities of six cephalosporin antibiotics (cephalexin, cefuroxime, cefdinir, …

Éthiopie (code pays fourni par la source)

Chemical composition and evaluation of antioxidant and insecticidal activities of smoke from Azadirachta indica (neem) leaves

Kibrom Teshome, Melaku Assefa, Jibrel Abdulkadir Emam, Estifanos Ele Yaya

This study investigated the chemical composition, antioxidant, and insecticidal properties of leaf smoke from Azadirachta indica (neem) extracted with n-hexane and methanol. GC-MS analysis revealed that the n-hexane-trapped extract was dominated by methyl hexadecanoate (64.27%) and methyl stearate (25.86%). The methanol-trapped extract …

Éthiopie (code pays fourni par la source)

Phytochemical investigation of Euphorbia abyssinica: Isolation and structural elucidation of secondary metabolites

Jibrel Abdulkadir Emam, Estifanos Ele Yaya

The present study investigated the phytochemical constituents of Euphorbia abyssinica Gmel. The crude 80% ethanol extract was partitioned between EtOAc and water, and the EtOAc fraction was subjected to chromatographic fractionation, yielding twelve compounds: one sterol (β-sitosterol, 1); one sterol-glucoside (sitosterol-3-O-β-D-glucoside, 2); …

Éthiopie (code pays fourni par la source)

Antifungal, antioxidant, and antibacterial activities of C. macrostachyus plant leaves extracts using different solvents

Birhanu Ayalew Tebeje, Ayalew Temesgen Wodajo, Shewaye Lakew Mekuria, Gizachew Mulugeta Manahelohe et autres

The need for natural product-based bioactive plants with synergistic antioxidant and antibacterial properties is rapidly increasing worldwide. This study focuses on evaluating the antioxidant, antibacterial, and antifungal potential of C. macrostachyus Hochst . Ex Delile, which is frequently used in traditional settings …

Éthiopie (code pays fourni par la source)

Essential oil analysis and isolation of bioactive compounds from the leaf of Myrica salicifolia: Computational pharmacokinetics and toxicity assessment

Abraham Dilnesa Gashaw, Kibrom Gebreheiwot Bedane, Taye Beyene Demissie, Japheth Omollo Ombito et autres

This study investigates the chemical composition of essential oils and isolates bioactive compounds from the leaves of Myrica salicifolia, a plant used in traditional Ethiopian medicine. Gas Chromatography-Mass Spectrometry (GC-MS) analysis of the essential oils of the leaves of the plant resulted …

Éthiopie, Botswana (code pays fourni par la source)

Development and validation of HPLC-DAD method for the simultaneous determination of different classes of antibiotic residues in root, leafy and fruit-bearing vegetables preceded by effervescence-assisted dispersive liquid-liquid micro extraction (EA-DLLME)

Serkalem Abera, Estifanos Ele Yaya, Bhagwan Singh Chandravanshi

Éthiopie (code pays fourni par la source)

A comprehensive review-current development in spectroscopic and chromatographic techniques for natural product analysis

Abraham Dilnesa Gashaw, Mekonnen Abebayehu Desta, Estifanos Ele Yaya

Current research on plant secondary metabolites is limited by low detection sensitivity, incomplete spectral databases, and challenges in separating complex mixtures. Structural elucidation remains labor-intensive, and spatial or temporal analysis tools lack resolution. Poor standardization and limited integration with functional assays further …

Éthiopie (code pays fourni par la source)

Cytotoxicity of compounds isolated from Euphorbia abyssinica: A combined experimental and docking studies

Jibrel Abdulkadir Emam, Teshome Degfie Beshah, Taye Beyene Demissie, Tetemke Mehari Gebremedhin et autres

Euphorbia abyssinica Gmel. has been traditionally used in Ethiopia to treat various diseases, including swelling and cancer. This study assessed the cytotoxic effects of the ethanolic crude extract and its isolates from the aerial parts of E. abyssinica using the MTT assay …

Éthiopie, Botswana (code pays fourni par la source)

Development of HPLC-DAD method for the separation and simultaneous determination of ten antibiotic residues in food and environmental samples using surface floating organic droplet-based air-assisted liquid-liquid micro-extraction

Serkalem Abera, Estifanos Ele Yaya, Bhagwan Singh Chandravanshi

Éthiopie (code pays fourni par la source)

A Comprehensive Review-Current Development in Spectroscopic and Chromatographic Techniques for Natural Product Analysis

Abraham Gashaw, Mekonnen Abebayehu, Estifanos Ele Yaya