Jini Qiu

Mucoadhesive recombinant human catalase for dry eye disease: From protein engineering to first-in-human study

Ming Shao, Yiteng Lu, Wenjie Xie, Annan Lu et autres

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Secondary corneal amyloidosis in a patient with Meesmann corneal dystrophy

Jini Qiu, Y Li, Rongrong Cai, Chaoran Zhang

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Three-dimensional assessment of posterior polymorphous corneal dystrophy with swept-source optical coherence tomography

Jini Qiu, Lijia Tian, Yuhong Chen, Qihua Le et autres

Background: Posterior polymorphous corneal dystrophy (PPCD), also known as Schlichting dystrophy, can present as either autosomal dominant or isolated unilateral cases, with a similar phenotype but without a hereditary pattern. This study aimed to investigate the characteristics of PPCD using wide-field, high-resolution, …

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METTL3-m6A-mediated TGF-β signaling promotes Fuchs endothelial corneal dystrophy via regulating corneal endothelial-to-mesenchymal transition

Jini Qiu, Xueling Zhang, Qian Shi, Yujing Yang et autres

Abstract Fuchs endothelial corneal dystrophy (FECD) is the leading cause of vision-threatening corneal endothelial dystrophy without pharmacologic treatments. Corneal endothelial-mesenchymal transition (cEndMT), a specific cellular phenotypic transition, is implicated in the vicious cycle in FECD pathogenesis. Here, we investigated the reversible epigenetic …

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N-methyladenosine (m6A) modification regulates HSPA1A and HSPA1B expression in Müller cells under high glucose stress

Hong Yang, Jini Qiu, Xueling Zhang, Rongmei Zhou et autres

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Anatomic characteristics of the lacrimal sac and adjacent bony structures–a computed tomographic-dacryocystography research

Xinhan Cui, Limin Zhang, Jini Qiu, Chaoran Zhang et autres

AIM: To describe the anatomic characteristics of the lacrimal sac and its adjacent bone structures and to provide surgical recommendations for endoscopic dacryocystorhinostomy (EN-DCR). METHODS: This retrospective comparative study involved 118 sides with complete nasolacrimal duct obstruction and 83 unaffected sides from …

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Rapid detection of guttae area using aniline blue staining in Fuchs endothelial corneal dystrophy mouse model

Xueling Zhang, Jini Qiu, Yalan Feng, Jijia Zheng et autres

Fuchs endothelial corneal dystrophy (FECD) is a leading cause of corneal endothelial degeneration resulting in impaired visual acuity. Excessive deposition of extracellular matrix (guttae) on Descemet's membrane (DM) is the hallmark of FECD. We sought to detect the guttae area rapidly using …

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Long noncoding RNA ZFAS1: A novel anti-apoptotic target in Fuchs endothelial corneal dystrophy

Jini Qiu, Ruiping Gu, Qian Shi, Xueling Zhang et autres

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Single-cell RNA sequencing reveals the complex cellular niche of pterygium

Xueling Zhang, Jini Qiu, Feifei Huang, Qiting Luo et autres

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Anatomic Characteristics of the Lacrimal Sac and Adjacent Bony Structures - A Computed Tomographic-Dacryocystography Study

Xinhan Cui, Yanwen Fang, Limin Zhang, Jini Qiu et autres

Abstract Purpose To describe the anatomic characteristics of the lacrimal sac and its adjacent bone structures and to provide surgical recommendations for endoscopic dacryocystorhinostomy (EN - DCR) in Asians. Methods This retrospective comparative study involved 118 sides with complete nasolacrimal duct obstruction …

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Herpes Simplex Keratitis as a Complication of Pterygium Surgery

Xinhan Cui, Jini Qiu, Feifei Huang, Chaoran Zhang et autres

BACKGROUND Infectious keratitis after pterygium surgery is a rare but potentially devastating complication. The present study presents 5 cases of herpes simplex keratitis (HSK) after pterygium surgery. CASE REPORT This study was conducted in our clinic in a 5-year period from February …

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Corneal biomechanical properties in vernal keratoconjunctivitis and its subtypes: a preliminary study

Xueling Zhang, Feifei Huang, Jini Qiu, Yujing Yang et autres

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