George Magoufis

Patient With Bilateral Infracts and Vasculitis With Graft vs Host Disease

Alexandros Stavros Triantafyllou, Angeliki Sterpi, Aikaterini Theodorou, Maria Chondrogianni et autres

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Endovascular Treatment in Acute Ischemic Stroke Due to Occlusion of Medium or Distal Vessels

Lina Palaiodimou, Apostolοs Safouris, Nikolaos M. Papageorgiou, Konstantinos Melanis et autres

BACKGROUND AND OBJECTIVES: Endovascular treatment (EVT) is the standard of care for acute ischemic stroke (AIS) due to large vessel occlusions, but its efficacy and safety in medium or distal vessel occlusions (MDVOs) remain uncertain. This systematic review and meta-analysis evaluated EVT …

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The Added Benefit of Intra‐Arterial Thrombolysis After Successful Recanalization by Endovascular Treatment: A Systematic Review and Meta‐Analysis of Randomized‐Controlled Clinical Trials

Lina Palaiodimou, Νικόλαος Παπαγεωργίου, Guillaume Turc, Benjamin Gory et autres

BACKGROUND: Despite successful recanalization following endovascular thrombectomy (EVT) for acute ischemic stroke (AIS) with large-vessel occlusion (LVO), many patients fail to achieve excellent functional outcomes. Post-EVT intra-arterial thrombolysis (IAT) has emerged as a potential adjunctive strategy to improve microvascular reperfusion and clinical …

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Endovascular therapy versus best medical treatment for symptomatic intracranial atherosclerotic stenosis: A systematic review and meta-analysis

Maria‐Ioanna Stefanou, Lina Palaiodimou, Aikaterini Theodorou, George Magoufis et autres

Abstract Introduction Evidence on endovascular therapy (EVT) for symptomatic intracranial stenosis (sICAS) from randomized-controlled clinical trials (RCTs) is conflicting. While prior RCTs on percutaneous transluminal angioplasty and stenting (PTAS) demonstrated harm or no benefit over best medical treatment (BMT), recent data suggest …

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Safety and Efficacy of Endovascular Therapy in Distal Vessel Occlusions

Apostolοs Safouris, Lina Palaiodimou, George Magoufis, Odysseas Kargiotis et autres

Endovascular therapy (EVT) is strongly indicated for acute ischemic stroke (AIS) caused by large vessel occlusion (LVO) in the anterior and posterior circulation according to international recommendations, but the benefit is unclear for AIS patients with distal vessel occlusions (DVO) since these …

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Prevalence, diagnosis and management of intracranial atherosclerosis in White populations: a narrative review

Maria‐Ioanna Stefanou, George Magoufis, Apostolοs Safouris, Odysseas Kargiotis et autres

BACKGROUND: Intracranial atherosclerotic disease (ICAD) represents a leading cause of ischemic stroke worldwide, conferring increased risk of recurrent stroke and poor clinical outcomes among stroke survivors. Emerging evidence indicates a paradigm shift, pointing towards increasing detection rates of ICAD among White populations …

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Update of Anticoagulation Use in Cardioembolic Stroke With a Special Reference to Endovascular Treatment

Apostolοs Safouris, Klearchos Psychogios, Lina Palaiodimou, Péter Orosz et autres

Cardioembolic stroke is a major cause of morbidity, with a high risk of recurrence, and anticoagulation represents the mainstay of secondary stroke prevention in most patients. The implementation of endovascular treatment in routine clinical practice complicates the decision to initiate anticoagulation, especially …

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Medical Management Versus Endovascular Treatment for Large-Vessel Occlusion Anterior Circulation Stroke With Low NIHSS

Apostolοs Safouris, Lina Palaiodimou, Sándor Nardai, Odysseas Kargiotis et autres

BACKGROUND: Endovascular treatment (EVT) for acute ischemic stroke (AIS) patients presenting with National Institutes of Health Stroke Scale score of 0 to 5 is common in clinical practice but has not yet been proven safe and effective. Our objective is to assess …

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Endovascular treatment for anterior circulation large-vessel occlusion ischemic stroke with low ASPECTS: a systematic review and meta-analysis

Apostolοs Safouris, Lina Palaiodimou, István Szikora, Odysseas Kargiotis et autres

Background: Endovascular treatment (EVT) for acute ischemic stroke (AIS) patients presenting with Alberta Stroke Program Early CT Score (ASPECTS) 0-5 has not yet proven safe and effective by clinical trials. Objectives: The aim of the study was to assess whether EVT in …

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Intravenous thrombolysis for large vessel or distal occlusions presenting with mild stroke severity

Georgios Tsivgoulis, Nikhil Goyal, AH Katsanos, Konark Malhotra et autres

Utility of Intravenous Alteplase Prior to Endovascular Stroke Treatment

Aristeidis H. Katsanos, Guillaume Turc, Marios Psychogios, Johannes Kaesmacher et autres

OBJECTIVE: To provide a critical appraisal on the evidence from randomized controlled clinical trials (RCTs) on the utility of direct endovascular treatment (dEVT) compared to the combination of endovascular treatment preceded by IV thrombolysis (bridging therapy [BT]) for patients with acute large …

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Foramen magnum arteriovenous fistula presenting as transverse myelitis

Artemios Artemiadis, George Magoufis, Timotheos-Stefanos Papadopoulos, Katerina Zekiou et autres

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