Jerzy Niemirowicz

PALB2 mutations and prostate cancer risk and survival

Dominika Wokołorczyk, Wojciech Kluźniak, Klaudia Stempa, Bogna Rusak et autres

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A common nonsense mutation of the BLM gene and prostate cancer risk and survival

Andrzej Antczak, Wojciech Kluźniak, Dominika Wokołorczyk, Aniruddh Kashyap et autres

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The presence of prostate cancer at biopsy is predicted by a number of genetic variants

Aniruddh Kashyap, Wojciech Kluźniak, Dominika Wokołorczyk, Adam Gołąb et autres

Several single nucleotide polymorphisms (SNPs) have been associated with an elevated risk of prostate cancer risk. It is not established if they are useful in predicting the presence of prostate cancer at biopsy or if they can be used to define a …

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The G84E mutation in the HOXB13 gene is associated with an increased risk of prostate cancer in Poland

Wojciech Kluźniak, Dominika Wokołorczyk, Aniruddh Kashyap, Anna Jakubowska et autres

BACKGROUND: The G84E mutation in the HOXB13 gene has been associated with a high lifetime risk of prostate cancer in North America (about 20-fold). The geographical and ethnic extent of this recurrent allele has not yet been determined. METHODS: We assayed for …

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An inherited NBN mutation is associated with poor prognosis prostate cancer

Cezary Cybulski, Dominika Wokołorczyk, Wojciech Kluźniak, Anna Jakubowska et autres

BACKGROUND: To establish the contribution of eight founder alleles in three DNA damage repair genes (BRCA1, CHEK2 and NBS1) to prostate cancer in Poland, and to measure the impact of these variants on survival among patients. METHODS: Three thousand seven hundred fifty …

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Erratum

Piotr Kaczmarek, Lech Pokoca, Jerzy Niemirowicz, Ewa Majewska et autres

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[Assessment of 8-hydroxy-2'-deoxyguanosine concentrations in bladder cancer patients treated with intravesical BCG instillation].

Piotr Kaczmarek, Jan Błaszczyk, Paweł Fijałkowski, Anna Sierakowska-Fijałek et autres

UNLABELLED: Increased 8-hydroxy-2'-deoxyguanosine (8-OHdG) concentration has been proposed as reliable marker of the oxidative DNA damage, and prognostication of urological carcinogenesis, particularly in bladder cancer. Widely accepted method of treatment in early stages of bladder cancer is transurethral electro resection (TURN). Intravesical …

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[Evaluation of side effects after intrabladder instillations of preparations in patients with superficial bladder carcinoma].

Piotr Kaczmarek, Jan Błaszczyk, Jan Kowalski, Jerzy Niemirowicz

Permanent increase in neoplasm incidence including also bladder neoplasms makes physicians to search for new forms and methods of treatment. Application of new preparations entails in many cases appearance of side effects which are difficult to fight off and thus must be …

The influence of immunostimulation with BCG suspension on neutrophil function in patients with superficial bladder carcinoma

Piotr Kaczmarek, Jan Błaszczyk, Jerzy Niemirowicz

[Lipids peroxidation in platelets in patients with bladder cancer treated with Mycobacterium suspension].

P. Kaczmarek, Andrzej Buczyński, Jerzy Niemirowicz, Witold Gnitecki et autres

Platelet is blood's morphotic element in which intense energy metabolism takes place, which makes it possible to participate in the complex processes of the organism's homeostasis. The aim of the study was to analyse aerobic metabolism in the platelets, taking into consideration …

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