Paweł Fijałkowski

Computational dataset for ferric-ion association with ovotransferrin and lactoferrin across canonical and high-loading regimes

Piotr Fijałkowski, Riddhi Sainda, Oleksandra Pryshchepa, Grzegorz Trykowski et autres

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Computational dataset for ferric-ion association with ovotransferrin and lactoferrin across canonical and high-loading regimes

Piotr Fijałkowski, Riddhi Sainda, Oleksandra Pryshchepa, Grzegorz Trykowski et autres

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Evaluation of Bio-Based Solvents for Sustainable Extraction of Bioactive Constituents from Sea Buckthorn (Hippophae rhamnoides L.)

Natalia Gajewska, Magdalena Królikowska, Jolanta Wółkiewicz, Aneta Krakowska‐Sieprawska et autres

Sea buckthorn (Hippophae rhamnoides L.) fruits are a valuable source of bioactive compounds with potential applications in food, nutraceutical, and cosmetic formulations. In this study, the influence of extraction technique and solvent composition on the recovery of bioactive constituents from freeze-dried sea …

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Synergistic effects of lactoferrin in enhancing cisplatin activity: From molecular interactions to improved drug delivery systems

Paweł Fijałkowski, Katarzyna Niedojadło, Justyna Walczak‐Skierska, Oleksandra Pryshchepa et autres

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Multifunctional role of Lactoferrin in metal ion interactions and biomedical applications: A review

Paweł Fijałkowski, Paweł Piotr Pomastowski, Rudi van Eldik, Katarzyna Rafińska

Lactoferrin (Lf) is a multifunctional glycoprotein of the transferrin family that plays a crucial role in iron metabolism, immune regulation, and antimicrobial defense. This review explores the structural properties and metal-binding mechanisms of lactoferrin, highlighting its interactions with various metal ions including …

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Bacteriological Identification, Characterization and Changes of Feces Microbiome in Prostate Cancer Patients Undergoing Radiotherapy

Aleksandra Bogumiła Florkiewicz, Paweł Fijałkowski, Piotr Fijałkowski, Michał Złoch et autres

Purpose: To investigate the bacteriological characteristics of the gut microbiome in patients with prostate cancer and changes during and after radiation therapy. Patients and Methods: Forty-one prostate cancer (PCa) patients treated with radiation therapy were included in the study. Fecal samples were …

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Sustainable Extraction of Bioactive Phenolics from Rose Hips for Functional Food Applications: Evaluation of Green Solvents and Extraction Techniques

Hanna Kaczkowska, Marharyta Pestriakova, Jolanta Wółkiewicz, Aneta Krakowska‐Sieprawska et autres

Growing interest in sustainable functional food ingredients has accelerated the search for green extraction methods for bioactive compounds. This study systematically evaluates the use of three emerging green solvents, namely γ-valerolactone (GVL), Cyrene™, and ethyl lactate (EL), as alternatives to conventional solvents …

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MALDI-TOF mass spectrometry analysis of seasonal variations in culturable milk microbiota and physico-chemical properties in Poland: Implications for dairy management and quality control

Jagoda Pałczyńska, Oleksandra Pryshchepa, Agnieszka Ludwiczak, Piotr Fijałkowski et autres

The primary objective of this study was to systematically examine the seasonal fluctuations within the milk microbiome with the use of MALDI-TOF-MS technique. Moreover, the quality of milk was evaluated based on the basic milk parameters such as total protein and fat …

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Analysis of the efficacy of MALDI-TOF MS technology in identifying microorganisms in cancer patients and oncology hospital environment

Grażyna Czeszewska-Rosiak, Iwona Adamczyk, Agnieszka Ludwiczak, Piotr Fijałkowski et autres

Rapid diagnostics of microbes in hospitals are crucial for promptly identifying infections, enabling timely and appropriate treatment. The study was conducted to evaluate the effectiveness of the matrix-assisted laser desorption ionization time-of-flight mass spectrometry (MALDI TOF MS) technology in the microbial profiling …

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Synthesis of nanoparticles of cobalt protoporphyrin IX (Co( iii )PPIX NPs). Antiradical, cytotoxicity and antibacterial properties

Piotr Fijałkowski, Olga Impert, Paweł Piotr Pomastowski, Katarzyna Rafińska et autres

Co( iii )PPIX nanoparticles were synthesized and their physicochemical properties were characterized. Furthermore, their biological properties were investigated, including antibacterial activity, antioxidant activity, and cytotoxicity test.

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Study of guanidine-containing oligomer for desinfectant application

H. Hodlevskyi, A. Hudyma, Polina Vakuliuk, Oleksandra Pryshchepa et autres

The purpose of this project is a creation of guanidine containing oligomer, that could be used as a disinfectant against multiresistant microorganisms.

Enhancing wound healing with zinc and silver nanocomposites synthesized with β-lactoglobulin: antimicrobial properties, collagen deposition, and systemic effects in a C57BL/6J mouse model

Agnieszka Rodzik, Paweł Piotr Pomastowski, Magdalena Buszewska‐Forajta, Viorica Railean et autres

This study explores the potential of zinc and silver nanocomposites, synthesized with β-lactoglobulin, a whey protein, in promoting wound healing, using the C57BL/6J mouse model. Our research is distinct in its dual focus: assessing the antimicrobial efficacy of these nanocomposites and their …

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