Rozhgar A. Khailany

Expression of miR-101-3p and its target ADAM15 gene in colorectal cancer patients

Anya Omed, Rozhgar A. Khailany

Purpose: This study aims to evaluate the expression patterns of miR-101-3p and its target ADAM15 in colorectal cancer patients. Materials and Methods: Thirty patients with colorectal cancer had their tumor and corresponding normal tissue samples taken. Following RNA extraction, real-time PCR (qRT-PCR) …

iq (code pays fourni par la source)

A novel missense variant of the RHAG gene in the first Iraqi case of the Rh‐null phenotype

Muqdad M. N. Al‐Mousawi, Saad S. Merza, Rozhgar A. Khailany, Ali Abdulghani Ramadhan et autres

All data of relevance to the case has been presented in the manuscript.

iq (code pays fourni par la source)

Hemoglobin Dieppe ( HBB:c. 383A > G ): A Rare Dominant β-Thalassemia in an Iraqi Kurdish Family

Tara Jamel Osman, Rozhgar A. Khailany, Luqman Khalid Rasool, Nasir A.S. Al-Allawi

Dominant β-thalassemia is a rare form of thalassemia that is caused by a heterogenous group of molecular defects, including missense, nonsense, and frameshift mutations. Among the missense mutations involving the third exon of β-globin gene is the rare Hb Dieppe (HBB:c. 383A …

iq (code pays fourni par la source)

Hb SKMC and an unprecedented γδβ-thalassemia: first report from Iraq

Rawand Shamoon, Amir Charkaneh, Elena Di Pierro, Milena Agata Irrera et autres

Background Thalassemias are genetic disorders of globin chain synthesis. In Iraq, β-thalassemia is more prevalent than α-thalassemia. This study identifies two unpredicted globin gene mutations, a rare α-globin gene mutation (Hb SKMC) and a novel γδβ-thalassemia deletion.Methods Over 2 years, the Genetics …

iq, it (code pays fourni par la source)

Biallelic null variants in PNPLA8 cause microcephaly by reducing the number of basal radial glia

Yuji Nakamura, Issei S. Shimada, Reza Maroofian, Micol Falabella et autres

Patatin-like phospholipase domain-containing lipase 8 (PNPLA8), one of the calcium-independent phospholipase A2 enzymes, is involved in various physiological processes through the maintenance of membrane phospholipids. Biallelic variants in PNPLA8 have been associated with a range of paediatric neurodegenerative disorders. However, the phenotypic …

jp, gb, Égypte, ir, de, sa, fr, us, iq, tr, pk (code pays fourni par la source)

Histopathologic Changes and Molecular Characterization of Fascioliasis (a Zoonotic Disease) among Slaughtered Livestock in Erbil and Halabja Abattoirs, Kurdistan Region-Iraq

Qaraman M.K. Koyee, Rozhgar A. Khailany, Mahmud Luqman Rahman, Liza Numan Nassraldin

داء حلزون كبد الاغنام (المتورقات) الناجم عن Fasciola (F.) hepatica وF. gigantica مرض معد يصيب الإنسان والحيوانات المجترة في العديد من دول العالم، بما في ذلك العراق. إن دراسة هذه الطفيليات، وتأثيراتها الضارة على مختلف المضائف، شكليًا ، نسيجيا ، وبائيًا وجزيئيًا …

iq (code pays fourni par la source)

KRAS and MT-CO1 genes in colorectal cancer: a molecular investigation

Harmand Ali Hama, Bestoon S. Hasan, Basak T. Barzngy, Saman S. Abdulla et autres

Colorectal cancer (CRC) is the third leading cause of cancer-related deaths worldwide. The tumor suppressor gene MT-CO1, and Kristen Rat Sarcoma Virus (KRAS), an oncogene are primarily responsible for controlling cell apoptosis, cell cycle arrest, and cell proliferation, and any irregularities in …

iq, pl (code pays fourni par la source)

Biallelic null variants in PNPLA8 cause microcephaly through the reduced abundance of basal radial glia

Yuji Nakamura, Issei S. Shimada, Reza Maroofian, Henry Houlden et autres

Abstract PNPLA8, one of the calcium-independent phospholipase A2 enzymes, is involved in various physiological processes through the maintenance of membrane phospholipids. However, little is known about its role in brain development. Here, we report 12 individuals from 10 unrelated families with biallelic …

jp, gb, ir, de, sa, fr, Égypte, us, iq, tr (code pays fourni par la source)

Expression patterns of LncRNA-GAS5 and its target APOBEC3C gene through miR-103 in breast cancer patients

Belan O. Kanabe, Mehmet Özaslan, Sherwan Ahmed Aziz, Mustafa S. Al-Attar et autres

Early diagnosis of breast cancer can increase the survivability of the patients and the patient's quality of life. There is growing evidence demonstrating the active role of LncRNA-GAS5 and miR-103 in cancer biology. APOBEC enzymes are important players in immunity and may …

tr, iq (code pays fourni par la source)

Exonic sequencing and MLH3 gene expression analysis of breast cancer patients

Rozhgar A. Khailany, Mehmet Özaslan

Breast cancer is the most common cancer in women worldwide. Detection of breast cancer susceptibility genes is an important issue. Also, MLH3 is a DNA mismatch repair gene and mutation in this gene is harmful in different cancers. This study aimed to …

tr (code pays fourni par la source)

A Novel β0-Thalassemia Mutation,HBB: c.356_357delTT [Codon 118 (–TT)] in an Iraqi Kurd

Sulav D. Atroshi, Nasir A.S. Al-Allawi, David H.K. Chui, Hossein Najmabadi et autres

We report a novel frameshift β-thalassemia (β-thal) mutation due to a two-nucleotide deletion at codon 118 of the β-globin gene (HBB: c.356_357delTT) in a 4-year-old Iraqi Kurd female presenting as transfusion-dependent β-thal. This frameshift mutation, unlike many others involving the third exon, …

iq, us, ir (code pays fourni par la source)

The Relevance of SNPs at 3′UTR Region of CASP7 and miR-371b-5p Associated Diseases: A Computational Analysis

Sana Zaheer, Rozhgar A. Khailany, Sadaf Parvez, Muhammad Naveed et autres

tr, pk, iq, cn (code pays fourni par la source)