Qian Cai

A novel method for real-time adulteration identification of heated-honey processed Astragali radix using REIMS-iKnife and its regulatory effects on gut microbiota, SCFAs, and immune function in spleen-deficient rats

Pengpeng Liu, Yisheng Xu, Haoran Yu, Tianzhu Jia et autres

Background: Astragali radix (AR) is a well-known traditional Chinese medicine (TCM). AR processed with heated honey (HAR) can enhance the effect in treating spleen deficiency. However, some people have used heated sugar as a substitute for heated honey in processing AR. The …

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Bran-frying induces relative arabinose enrichment and moderate macromolecular aggregation from Atractylodis Rhizoma, resulting in enhanced anti-gastric cancer activity

Huiying Xu, Jiayang Ling, Liting Zhou, Wanting Zeng et autres

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Aconitum coreanum (H.Lév l.) Rapaics exerts neuroprotective effects on cerebral ischemic stroke by inhibiting autophagy through the AMPK/mTOR/ULK1 pathway

Yue Liu, Yang Qu, Qian Cai

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Protective Effects of Pectin From Honey‐Processed Hawthorn on Acute Myocardial Ischemia

Huijuan Li, M. H. Liu, Yu Zheng, Qian Cai et autres

Previous studies have shown that both hawthorn and honey-processed hawthorn (HH) can prevent heart injury in acute myocardial ischemia (AMI). Hawthorn pectin (HP) and stir-fried hawthorn pectin (FHP) have been identified as protective agents against AMI, with the effects closely related to …

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Bibliometric and visualization analysis of cancer associated with intestinal flora through genetics and epigenetics from 1991 to 2024

Li Yang, Ke Shi, Hong Qi, Qian Cai et autres

BACKGROUND: Intestinal flora, or gut microbiota, has increasingly been recognized for its potential role in cancer development and progression. Beyond direct interactions with systemic organs, gut microbiota and its metabolites can modulate epigenetic processes such as DNA methylation, histone modification, and non-coding …

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The protective effects of water-soluble non-starch polysaccharides from Arctium lappa on LPS-induced acute lung injury in vitro and in vivo

Dan Wang, Haibo Yin, Liang Xu, Ting‐Guo Kang et autres

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Synergistic and Antagonistic Mechanisms of Arctium lappa L. Polyphenols on Human Neutrophil Elastase Inhibition: Insights from Molecular Docking and Enzymatic Kinetics

Yixun Sun, Mingbo Zhang, Yating Zhang, Yu Long Zheng et autres

This study systematically investigated the inhibitory mechanism of Arctium lappa L. polyphenols (ALP) against human neutrophil elastase (HNE). Molecular docking techniques were employed to predict the binding patterns and inhibition types between polyphenolic components and HNE, complemented by in vitro enzymatic tests …

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Profiling X chromosome genes expression relevant to sex dimorphism in stroke: insights from transcriptomics landscape analysis

Xiude Qin, Yuerong Li, Qian Cai, Jiaye Liu et autres

Introduction: Although age is the most important non-modifiable risk factor for cerebral stroke, it is also apparent that females commonly exhibit longer lifespan and better outcome after stroke compared to the age-matched males. A critical event after stroke is the peripheral infiltration …

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SynBioNanoDesign: pioneering targeted drug delivery with engineered nanomaterials

Qian Cai, Rui Feng Guo, Dafu Chen, Zixin Deng et autres

Synthetic biology and nanotechnology fusion represent a transformative approach promoting fundamental and clinical biomedical science development. In SynBioNanoDesign, biological systems are reimagined as dynamic and programmable materials to yield engineered nanomaterials with emerging and specific functionalities. This review elucidates a comprehensive examination …

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The Chemical Constituents and Anti‐Hyperlipidemia Effect of Salt‐Processed Fenugreek Seed

Yang Qu, Honghe Xiao, Mingyue Jiang, Qian Cai et autres

The seed of fenugreek (FS) was traditionally used in diets and as a spice in India, as well as medicine in China. It had anti-diabetic and anti-hypolipidemic effects. According to the theory of traditional Chinese medicine, the effects of FS were enhanced …

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[Proposal and research idea of "traditional Chinese medicine processing chemical biology"].

Pengpeng Liu, Qian Cai, Ji Shi, Nan Xu et autres

Traditional Chinese medicine(TCM) processing is a unique and highly distinctive pharmaceutical technology in China. Utilizing modern scientific methods to elucidate the connotations of traditional processing theory and its effects is expected to facilitate the inheritance, development, innovation, and enhancement of TCM processing, …

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Aconitum coreanum and processed products on its base prevent stroke via the PI3K/Akt and KEAP1/NRF2 in the in vivo study

Wan-ting Zeng, Liting Zhou, Ru Jia, Yue Liu et autres

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