Shu‐Chi Wang

Retraction Note: Sigma-2 receptor/TMEM97 agonist PB221 as an alternative drug for brain tumor

Chia-Chi Liu, Ching‐Fang Yu, Shu‐Chi Wang, Hsueh-Yin Li et autres

This article has been retracted. Please see the Retraction Notice for more detail: https://doi.org/10.1186/s12885-019-5700-7.

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Isoalantolactone Attenuates LPS-Induced Acute Lung Injury, an Effect Associated with Suppressed MAPK/STAT3 Activation and Epithelial-Mesenchymal Transition

Chia‐Yang Li, Chung-Wei Liu, Hsin-Han Tseng, Yu‐Hsin Tseng et autres

Background: Acute lung injury (ALI) is characterized by a high mortality rates and acute inflammation that compromises the epithelial and endothelial barriers of the respiratory system.Isoalantolactone (IsoA) is a natural compound derived from Inula helenium that has been shown to exhibit anti-inflammatory …

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Honokiol regulates Acute respiratory distress syndrome (ARDS)‐associated pulmonary fibrosis via the miR‐19a‐3p/POSTN axis

Wei‐Lun Liu, Hsiao-Hsuan Wang, Hsuanfu Kuo, Chia‐Hung Yen et autres

BACKGROUND AND PURPOSE: Acute respiratory distress syndrome (ARDS) and subsequent pulmonary fibrosis are associated with high mortality and limited treatment options. Periostin (POSTN) is a profibrotic mediator predicted to be regulated by microRNA-19a-3p (miR-19a-3p), but the relevance of this axis in ARDS-associated …

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Building Responsible Circular Capabilities through a Value Ladder in Bio Based SMEs

Shu‐Chi Wang, Yao-Ming Hong

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Epigenomics-Guided Multi-Omics Integration Uncovers a Lipid-Metabolic Signature with Translational Utility in Bladder Cancer

Yu-De Wang, Yo-Liang Lai, Chia-Hsin Liu, Yu‐Ting Su et autres

Background: Bladder cancer (BLCA) exhibits marked heterogeneity, and current classifiers provide limited guidance for prognosis or treatment. Because epigenetic reprogramming and metabolic rewiring jointly shape BLCA biology, we sought to identify epigenomically informed biomarkers with functional relevance. Methods: Epigenome (genome-wide promoter DNA …

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A 2.9-Gb/s Spread-Spectrum Clocking Transceiver Utilizing Phase Interpolation for EMI-Suppressed Chip-to-Chip Links

Ching-Yuan Yang, Shu‐Chi Wang, Wan-Yu Yu, Min-Shu Shih et autres

This paper presents a fully integrated 2.9-Gb/s spread-spectrum clocking (SSC) wireline transceiver designed for high-speed chip-to-chip links. The architecture combines a digitally controlled phase interpolator (DCPI) in the transmitter and an analog-controlled phase interpolator (ACPI) in the receiver, leveraging the programmability of …

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Glucose metabolism and its direct action in cancer and immune regulation: opportunities and challenges for metabolic targeting

Bo‐Syong Pan, Che-Chia Hsu, Hsin‐En Wu, Yuan-Ru Chen et autres

Glucose metabolism is a pivotal hub for cellular energy production and the generation of building blocks that support cell growth, survival, and differentiation. Cancer cells undergo metabolic reprogramming to sustain rapid proliferation, survive in harsh microenvironments, and resist therapies. Beyond producing energy …

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Anti-cancer effects of Psoralea corylifolia: insights into cancer hallmarks

Pin-Rong Chen, Ta‐Chen Su, Kun‐Che Chang, Chien‐Chih Chiu et autres

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Effects of Sofosbuvir/Velpatasvir Therapy on Extrahepatic Manifestations in Patients With Type 2 Diabetes and Chronic Hepatitis C: Insights From a Nationwide Hepatitis C Virus Registry in Taiwan

Szu‐Jen Wang, Te‐Sheng Chang, Gin‐Ho Lo, Chao‐Hung Hung et autres

This study examines the impact of hepatitis C virus (HCV) eradication through sofosbuvir/velpatasvir (SOF/VEL) treatment on glycated hemoglobin (HbA1c) levels in patients with chronic hepatitis C and type 2 diabetes mellitus (T2DM). Utilizing data from the Taiwan HCV Registry, a retrospective analysis …

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Retrospective analysis of steatosis effect on antiviral response and hepatocellular carcinoma risk in chronic hepatitis C

Saptarshi Bhattacharyya, Ming‐Lung Yu, Phumelele Yvonne Siphepho, Jee‐Fu Huang et autres

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Magnolol facilitates mitochondrial-peroxisome dysfunction and induces oxeiptosis in lung cancer cells following transfer via tunneling nanotubes

Meng‐Hsuan Cheng, Hsiao-Hsuan Wang, Mo Da-Sang Hua, Hsuan‐Fu Kuo et autres

Recent therapeutic advances have improved survival rates for patients with lung cancer. However, drug resistance remains a significant challenge and is closely linked to mitochondrial alterations in lung cancer cells. Magnolol, a compound extracted from Magnolia officinalis, has anti-cancer properties. However, its …

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Real‐world efficacy and safety of universal 8‐week glecaprevir/pibrentasvir in patients with chronic hepatitis C with early chronic kidney disease or pre‐end‐stage renal disease: Insights from a nationwide hepatisis C virus registry in Taiwan

S J Wang, Chung‐Feng Huang, Te Sheng Chang, C. Lo et autres

Abstract An 8‐week regimen of glecaprevir/pibrentasvir is recommended for treatment‐naïve patients with chronic hepatitis C (CHC). In alignment with the Taiwanese government's objective to eliminate hepatitis C by 2025, this study aimed to provide real‐world evidence on the use of this regimen …

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