Accès ouvert
2026
review
OpenAlex
Marco Dettori, Giovanna Deiana, Alessandra Palmieri, Antonella Arghittu et autres
Background and Objectives: Dengue is emerging as a multifaceted public health challenge that extends beyond traditional vector-borne disease frameworks. Climate change, rapid urbanisation, environmental transformation, global mobility, and digital ecosystems are progressively reshaping transmission dynamics, outbreak patterns, and preparedness needs worldwide. This …
it, in, se
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Accès ouvert
2025
article
OpenAlex
Giovanna Deiana, Isabella Figoni, Antonella Arghittu, Guglielmo Campus et autres
Background and Objectives: Climate change is modifying the ecological and climatic conditions that influence the distribution and activity of arthropod vectors. Rising temperatures and prolonged warm seasons have favored the establishment of Aedes albopictus in Mediterranean regions, increasing the risk of autochthonous …
it, in, se
(code pays fourni par la source)
2025
article
OpenAlex
Kate S. Cuschieri, Ardashel Latsuzbaia, Hana McMahon, Chiara Giubbi et autres
AIMS: Given the increasing adoption of self-sampling in cervical cancer screening, it is essential to evaluate the performance of human papillomavirus (HPV) tests in this context. The aim of the present work was to assess the accuracy of the Papilloplex high-risk (HR)-HPV …
gb, be, it
(code pays fourni par la source)
Accès ouvert
2025
article
OpenAlex
Mariangela Valentina Puci, Maria Alessandra Sotgiu, Narcisa Muresu, Laura Saderi et autres
Postmortem body donation (BD) plays a central role in medical education and scientific research. Sociocultural, religious, and legal factors can influence attitudes toward BD. In Italy, BD programs are in early development, and recent legislation (Law 10/2020) regulating body donation came into …
it
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Accès ouvert
2025
article
OpenAlex
Narcisa Muresu, Illari Sechi, Mariangela Valentina Puci, Marco Dettori et autres
BACKGROUND: Several studies highlighted that tailored health communication interventions improve cervical screening participation, vaccination coverage, and awareness about self-sampling benefits. The "COMUNISS" project was aimed at increasing awareness about cervical cancer prevention, identifying barriers to screening, and promoting screening uptake in under-screened …
it
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Chiara Giubbi, Marianna Martinelli, Ardashel Latsuzbaia, Kate S. Cuschieri et autres
The introduction of self-sampling in cervical cancer screening has raised the importance of HPV test validation on self-collected samples. This study aimed to evaluate the clinical accuracy of the OncoPredict HPV Screening (SCR) assay on self-collected vaginal and first-void urine (FVU) samples, …
it, be, gb
(code pays fourni par la source)
Accès ouvert
2024
article
OpenAlex
Ardashel Latsuzbaia, Marianna Martinelli, Chiara Giubbi, Kate S. Cuschieri et autres
BACKGROUND: The VALHUDES initiative was established to assess the clinical accuracy of HPV assays to detect cervical precancers using urine and vaginal self-samples compared to cervical clinician-collected samples. Here, the clinical performance of OncoPredict HPV Quantitative Typing (QT) assay (OncoPredict QT) was …
be, it, gb
(code pays fourni par la source)
Accès ouvert
2024
review
OpenAlex
Narcisa Muresu, Mariangela Valentina Puci, Giovanni Sotgiu, Illari Sechi et autres
INTRODUCTION: DNA methylation-based biomarkers have been investigated as useful tools in the carcinogenesis process, including the triage of HPV-associated cancers. In this context, we conducted a systematic review and meta-analysis focused on evaluating the changes in the level of DNA methylation in …
it
(code pays fourni par la source)
2024
preprint
OpenAlex
Chiara Giubbi, Marianna Martinelli, Ardashel Latsuzbaia, Kate S. Cuschieri et autres
The introduction of self-sampling in cervical cancer screening has raised the importance of HPV testvalidation on self-collected samples. This study aimed to evaluate the clinical performance of the OncoPredict HPV Screening (SCR) assay on self-collected vaginal and first-void urine (FVU) as part …
it, be, gb
(code pays fourni par la source)
Accès ouvert
2024
preprint
OpenAlex
Chiara Giubbi, Chiara Villa, Maria Letizia Di Meo, Illari Sechi et autres
HPV51 belongs to group I high-risk HPV (hrHPV) genotypes with a high prevalence of infection in numerous epidemiological studies, although its occurrence varies across geographical regions. To better understand the presence of variants and genetic variation of HPV51, this study aimed to …
it
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Accès ouvert
2024
article
OpenAlex
Narcisa Muresu, Mariangela Valentina Puci, Giovanni Sotgiu, Illari Sechi et autres
BACKGROUND: Epigenetic biomarkers in cancer have emerged as promising tools for early detection, prognosis, and treatment response prediction. In cervical cells, hypermethylation of the host and viral HPV-genome increases with the severity of lesions, providing a useful biomarker in the triage of …
it
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Accès ouvert
2024
article
OpenAlex
Andrea Fausto Piana, Giovanni Sotgiu, Paolo Castiglia, Stefania Pischedda et autres
Human papillomaviruses (HPVs) comprise more than 180 genotypes. HPV infection is mainly diagnosed by molecular methods. The aim of our study was to review the main molecular methods used to diagnose HPV infection, underscoring their characteristics. Several methods have been developed for …
it
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